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SNP rs861539
Basic Information
Name
rs861539
Chromosome
14
Position
103699416
Weight of evidence
48
Genotype Frequency
AG
GG
AA
CC
--
TC
47%
40%
13%
Allele Frequency
A
T
G
C
-
36%
64%
Additional Information
SNPedia (1)
PLoS (17)
Mendeley (9)
Personal Genome Project (0)
Genome.gov (0)
Other users (1715)
Comments (0)
Links to SNPedia
Title
Summary
rs861539 A/A
No summary provided.
Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).
Publications on this SNP on the Public Library of Science:
First Author
Title
Year of Publication
# of readers
Ching-Yu Lai
Tumor Site- and Stage-Specific Associations between Allelic Variants of Glutathione S-Transferase and DNA-Repair Genes and Overall Survival in Colorectal Cancer Patients Receiving 5-Fluorouracil-Based Chemotherapy
2013
1907
Peijian Ding
The Relationship between Seven Common Polymorphisms from Five DNA Repair Genes and the Risk for Breast Cancer in Northern Chinese Women
2014
2098
Goutham Hassan Venkatesh
Polymorphisms in Radio-Responsive Genes and Its Association with Acute Toxicity among Head and Neck Cancer Patients
2014
3638
Mantang Qiu
XRCC3 Thr241Met Is Associated with Response to Platinum-Based Chemotherapy but Not Survival in Advanced Non-Small Cell Lung Cancer
2013
1578
Amit A. Negandhi
MTHFR
Glu429Ala and
ERCC5
His46His Polymorphisms Are Associated with Prognosis in Colorectal Cancer Patients: Analysis of Two Independent Cohorts from Newfoundland
2013
3424
Ming Yin
Polymorphisms of Homologous Recombination Genes and Clinical Outcomes of Non-Small Cell Lung Cancer Patients Treated with Definitive Radiotherapy
2011
4251
Xiao-yong Shen
XRCC3 Thr241Met Polymorphism and Clinical Outcomes of NSCLC Patients Receiving Platinum-Based Chemotherapy: A Systematic Review and Meta-Analysis
2013
1933
Xu Chen
XRCC3
C18067T Polymorphism Contributes a Decreased Risk to Both Basal Cell Carcinoma and Squamous Cell Carcinoma: Evidence from a Meta-Analysis
2014
1839
Yazhou He
Impact of
XRCC2
Arg188His Polymorphism on Cancer Susceptibility: A Meta-Analysis
2014
2530
Shujie Guo
The Relationship between
XRCC1
and
XRCC3
Gene Polymorphisms and Lung Cancer Risk in Northeastern Chinese
2013
2683
Guohua Huang
Association between XRCC1 and XRCC3 Polymorphisms with Lung Cancer Risk: A Meta-Analysis from Case-Control Studies
2013
3047
Yu-Zhe Song
Association between Single Nucleotide Polymorphisms in
XRCC3
and Radiation-Induced Adverse Effects on Normal Tissue: A Meta-Analysis
2015
1827
Zoraida Verde
Are SNP-Smoking Association Studies Needed in Controls? DNA Repair Gene Polymorphisms and Smoking Intensity
2015
1373
Matthew A. Field
Reliably Detecting Clinically Important Variants Requires Both Combined Variant Calls and Optimized Filtering Strategies
2015
2776
Yanjing He
XRCC3
Thr241Met and
TYMS
variable number tandem repeat polymorphisms are associated with time-to-metastasis in colorectal cancer
2018
286
Olga Papadodima
Modulation of Pathways Underlying Distinct Cell Death Mechanisms in Two Human Lung Cancer Cell Lines in Response to S
N
1 Methylating Agents Treatment
2016
1402
Gabriela A. Martínez-Nava
Cervical Cancer Genetic Susceptibility: A Systematic Review and Meta-Analyses of Recent Evidence
2016
3987
Publications on this SNP on Mendeley
First Author
Title
Pub. Year
# of Readers
DOI
Ming Yin
Polymorphisms of homologous recombination genes and clinical outcomes of non-small cell lung cancer patients treated with definitive radiotherapy
2011
6
10.1371/journal.pone.0020055
G Ben Salah
An interethnic variability and a functional prediction of DNA repair Gene polymorphisms: The example of XRCC3 (p.Thr241>Met) and XPD (p.Lys751>Gln) in a healthy Tunisian population
2012
1
-
Chun-Lei Shi
Lack of association between XRCC3 rs861539 (C > T) polymorphism and lung cancer risks: an update meta-analysis.
2013
2
10.1007/s13277-013-0722-2
Susana N. Silva
Breast cancer risk and common single nucleotide polymorphisms in homologous recombination DNA repair pathway genes XRCC2, XRCC3, NBS1 and RAD51
2010
14
10.1016/j.canep.2009.11.002
Chun-Lei Shi
Lack of association between XRCC3 rs861539 (C > T) polymorphism and lung cancer risks: an update meta-analysis.
2013
1
10.1007/s13277-013-0722-2
Cheng Hong Yang
Single nucleotide polymorphism barcoding to evaluate oral cancer risk using odds ratio-based genetic algorithms
2012
0
10.1016/j.kjms.2012.02.002
Raju K Mandal
Polymorphic variants of DNA repair gene XRCC3 and XRCC7 and risk of prostate cancer: a study from North Indian population.
2010
1
-
Rama Devi Mittal
Gene variants of XRCC4 and XRCC3 and their association with risk for urothelial bladder cancer.
2012
1
10.1007/s11033-011-0906-z
Raju K Mandal
Polymorphic variants of DNA repair gene XRCC3 and XRCC7 and risk of prostate cancer: a study from North Indian population.
2010
1
10.1089/dna.2010.1047
Evidence compiled by the
Personal Genome Project
There are no results from the
Personal Genome Project
yet. Please come back later.
Publications listed by
Genome.gov
There are no results from
genome.gov
yet. Please come back later.
Users who share this SNP:
Genome Browser
Human GrCh38/hg38
Genome
Genes
Gene structures from GENCODE 21
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