SNP rs762551

Basic Information
Name rs762551
Chromosome 15
Position 74749576
Weight of evidence 51
Additional Information

Links to SNPedia

Title Summary
rs762551 A/A Fast caffeine metabolizer.
rs762551 C/C Cyp1a2 slow caffeine metabolizer.
rs762551 A/C Carrier of one cyp1a2*1f allele; slow caffeine metabolizer.
Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).

Publications on this SNP on Mendeley

First Author Title Pub. Year # of Readers DOI
U Ghoshal Genetic polymorphism of cytochrome P450 (CYP) 1A1, CYP1A2, and CYP2E1 genes modulate susceptibility to gastric cancer in patients with Helicobacter pylori infection 2013 1 Oa logo
Sofia Pavanello CYP1A2 polymorphisms, occupational and environmental exposures and risk of bladder cancer. 2010 3 -
Idris Guessous Caffeine intake and CYP1A2 variants associated with high caffeine intake protect non-smokers from hypertension. 2012 16 10.1093/hmg/dds137
Idris Guessous Caffeine intake and CYP1A2 variants associated with high caffeine intake protect non-smokers from hypertension. 2012 1 10.1093/hmg/dds137
H Wang CYP1A2 rs762551 polymorphism contributes to cancer susceptibility: a meta-analysis from 19 case-control studies 2012 3 10.1186/1471-2407-12-528Oa logo
H Wang CYP1A2 rs762551 polymorphism contributes to cancer susceptibility: a meta-analysis from 19 case-control studies 2012 0 10.1186/1471-2407-12-528Oa logo
B Laika Pharmacogenetics and olanzapine treatment: CYP1A2*1F and serotonergic polymorphisms influence therapeutic outcome. 2010 0 10.1038/tpj.2009.32Oa logo
Ulla Vogel Role of CYP1A2 polymorphisms on lung cancer risk in a prospective study 2012 0 10.1016/j.cancergen.2012.02.004Oa logo
Eng-King Tan Association between caffeine intake and risk of Parkinson's disease among fast and slow metabolizers. 2007 4 -
L Song Effect of CYP1A2 polymorphism on the pharmacokinetics of agomelatine in Chinese healthy male volunteers. 2014 2 10.1111/jcpt.12118
Hongge Wang CYP1A2 rs762551 polymorphism contributes to cancer susceptibility: a meta-analysis from 19 case-control studies. 2012 5 10.1186/1471-2407-12-528Oa logo
Sumitaka Kobayashi Genetic association of aromatic hydrocarbon receptor (AHR) and cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) polymorphisms with dioxin blood concentrations among pregnant Japanese women 2013 4 10.1016/j.toxlet.2013.03.013
Sofia Pavanello Role of CYP1A2 polymorphisms in breast cancer risk in women 2012 0 10.3892/mmr.2012.1164Oa logo
Zhong Tian Role of CYP1A2 1F polymorphism in cancer risk: evidence from a meta-analysis of 46 case-control studies. 2013 3 10.1016/j.gene.2013.04.038
Idris Guessous Caffeine intake and CYP1A2 variants associated with high caffeine intake protect non-smokers from hypertension. 2012 8 10.1093/hmg/dds137
Sofia Pavanello CYP1A2 polymorphisms, occupational and environmental exposures and risk of bladder cancer. 2010 0 10.1007/s10654-010-9479-8Oa logo
Sofia Pavanello Role of CYP1A2 polymorphisms on lung cancer risk in a prospective study. 2012 2 10.1016/j.cancergen.2012.02.004
A. G. Uitterlinden CYP1A2 and coffee intake and the modifying effect of sex, age, and smoking 2012 0 10.3945/ajcn.111.027102Oa logo
S Kobayashi Genetic association of aromatic hydrocarbon receptor (AHR) and cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) polymorphisms with dioxin blood concentrations among pregnant Japanese women 2013 1 -
Sofia Pavanello Role of CYP1A2 polymorphisms on lung cancer risk in a prospective study 2012 9 10.1016/j.cancergen.2012.02.004
Hongge Wang CYP1A2 rs762551 polymorphism contributes to cancer susceptibility: a meta-analysis from 19 case-control studies 2012 4 10.1186/1471-2407-12-528Oa logo
Eng-King Tan Association between caffeine intake and risk of Parkinson's disease among fast and slow metabolizers. 2007 0 10.1097/FPC.0b013e3282f09265Oa logo

Evidence compiled by the Personal Genome Project

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Publications listed by Genome.gov

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