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SNP rs699947
Basic Information
Name
rs699947
Chromosome
6
Position
43768652
Weight of evidence
89
Genotype Frequency
Allele Frequency
Additional Information
SNPedia (3)
PLoS (23)
Mendeley (28)
Personal Genome Project (0)
Genome.gov (0)
Other users (291)
Comments (0)
Links to SNPedia
Title
Summary
rs699947 A/C
1.36x increased risk for thyroid cancer in men
rs699947 A/A
1.36x increased risk for thyroid cancer in men
rs699947 C/C
Normal
Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).
Publications on this SNP on the Public Library of Science:
First Author
Title
Year of Publication
# of readers
Gallen Triana-Baltzer
Predictive Markers of Efficacy for an Angiopoietin-2 Targeting Therapeutic in Xenograft Models
2013
1832
Linda M. Dong
An Analysis of Growth, Differentiation and Apoptosis Genes with Risk of Renal Cancer
2009
4015
Helen R. Griffin
Genetic Variation in
VEGF
Does Not Contribute Significantly to the Risk of Congenital Cardiovascular Malformation
2009
3494
Ellen Iacobaeus
The Expression of VEGF-A Is Down Regulated in Peripheral Blood Mononuclear Cells of Patients with Secondary Progressive Multiple Sclerosis
2011
3815
Carol Lozano-Santos
Vascular Endothelial Growth Factor A (
VEGFA
) Gene Polymorphisms Have an Impact on Survival in a Subgroup of Indolent Patients with Chronic Lymphocytic Leukemia
2014
1497
Fotios Loupakis
Prospective Validation of Candidate SNPs of
VEGF/VEGFR
Pathway in Metastatic Colorectal Cancer Patients Treated with First-Line FOLFIRI Plus Bevacizumab
2013
3689
Young Seok Park
The Role of
VEGF
and
KDR
Polymorphisms in Moyamoya Disease and Collateral Revascularization
2012
3314
Daye Cheng
Vascular Endothelial Growth Factor +936C/T, –634G/C, –2578C/A, and –1154G/A Polymorphisms with Risk of Preeclampsia: A Meta-Analysis
2013
2444
Han Chen
Association between Variant Y402H in Age-Related Macular Degeneration (AMD) Susceptibility Gene
CFH
and Treatment Response of AMD: A Meta-Analysis
2012
4786
Mario Scartozzi
Role of Vascular Endothelial Growth Factor (VEGF) and VEGF-R Genotyping in Guiding the Metastatic Process in pT4a Resected Gastric Cancer Patients
2012
2404
Daniela Ruggiero
Genetics of VEGF Serum Variation in Human Isolated Populations of Cilento: Importance of VEGF Polymorphisms
2011
4005
Jian-Yang Gong
Association of
VEGF
Gene Polymorphisms with Diabetic Retinopathy: A Meta-Analysis
2013
1546
Montserrat García-Closas
Large-Scale Evaluation of Candidate Genes Identifies Associations between
VEGF
Polymorphisms and Bladder Cancer Risk
2007
8386
Helen R. Griffin
Genetic Variation in
VEGF
Does Not Contribute Significantly to the Risk of Congenital Cardiovascular Malformation
2009
4277
Montserrat García-Closas
Large-Scale Evaluation of Candidate Genes Identifies Associations between
VEGF
Polymorphisms and Bladder Cancer Risk
2007
7085
Ling Lin
Four Common Vascular Endothelial Growth Factor Polymorphisms (−2578C>A, −460C>T, +936C>T, and +405G>C) in Susceptibility to Lung Cancer: A Meta-Analysis
2013
2259
Ramon Andrade de Mello
The Impact of Polymorphic Variations in the 5p15, 6p12, 6p21 and 15q25
Loci
on the Risk and Prognosis of Portuguese Patients with Non-Small Cell Lung Cancer
2013
2189
Bhaskari Janardhan
Investigating impact of Vascular Endothelial Growth Factor Polymorphisms in Epithelial Ovarian Cancers: A Study in the Indian Population
2015
2000
Xinghua Xu
Association of VEGF Genetic Polymorphisms with Recurrent Spontaneous Abortion Risk: A Systematic Review and Meta-Analysis
2015
3049
Lei Wang
Association between Polymorphisms in Vascular Endothelial Growth Factor Gene and Response to Chemotherapies in Colorectal Cancer: A Meta-Analysis
2015
904
Tonia C. Rothuizen
Candidate Gene Analysis of Mortality in Dialysis Patients
2015
1645
Shu-Mei Yang
Joint Effect of Urinary Total Arsenic Level and VEGF-A Genetic Polymorphisms on the Recurrence of Renal Cell Carcinoma
2015
1431
Tadeusz Osadnik
The Relationships between Polymorphisms in Genes Encoding the Growth Factors TGF-β1, PDGFB, EGF, bFGF and VEGF-A and the Restenosis Process in Patients with Stable Coronary Artery Disease Treated with Bare Metal Stent
2016
2299
Publications on this SNP on Mendeley
First Author
Title
Pub. Year
# of Readers
DOI
Fotios Loupakis
Prospective Validation of Candidate SNPs of VEGF/VEGFR Pathway in Metastatic Colorectal Cancer Patients Treated with First-Line FOLFIRI Plus Bevacizumab
2013
9
10.1371/journal.pone.0066774
Min-Young Chun
Association of vascular endothelial growth factor polymorphisms with nonproliferative and proliferative diabetic retinopathy.
2010
2
-
E Kreiner-Møller
VEGFA variants are associated with pre-school lung function, but not neonatal lung function.
2013
1
10.1111/cea.12188
Idalia Garza-Veloz
No association between polymorphisms/haplotypes of the vascular endothelial growth factor gene and preeclampsia
2011
8
10.1186/1471-2393-11-35
P H Andraweera
The interaction between the maternal BMI and angiogenic gene polymorphisms associates with the risk of spontaneous preterm birth
2012
5
10.1093/molehr/gas016
S Lazzeri
VEGF-A polymorphisms predict short-term functional response to intravitreal ranibizumab in exudative age-related macular degeneration
2013
4
http://dx.doi.org/10.2217/pgs.13.43
Pi-Jung Hsiao
Vascular endothelial growth factor gene polymorphisms in thyroid cancer.
2007
0
Francesco Parmeggiani
Genetic Predictors of Response to PhotodynamicTherapy.
2011
2
10.2165/11592270-000000000-00000
E Kreiner-Møller
VEGFA variants are associated with pre-school lung function, but not neonatal lung function.
2013
6
10.1111/cea.12188
Mario Scartozzi
Role of vascular endothelial growth factor (VEGF) and VEGF-R genotyping in guiding the metastatic process in pT4a resected gastric cancer patients.
2012
10.1371/journal.pone.0038192
Qian Yuan
Association between promoter polymorphisms of vascular endothelial growth factor gene and sporadic Alzheimer's disease among Northern Chinese Han
2009
5
10.1016/j.neulet.2009.03.078
Fernando Cruz-Gonzalez
Predictive value of VEGF A and VEGFR2 polymorphisms in the response to intravitreal ranibizumab treatment for wet AMD.
2014
1
10.1007/s00417-014-2585-7
Helen R Griffin
Genetic Variation in VEGF Does Not Contribute Significantly to the Risk of Congenital Cardiovascular Malformation
2009
7
10.1371/journal.pone.0004978
Hussam Al-Kateb
Multiple variants in vascular endothelial growth factor (VEGFA) are risk factors for time to severe retinopathy in type 1 diabetes: the DCCT/EDIC genetics study.
2007
5
10.2337/db07-0376
Mar??a A. Jim??nez-Sousa
Genetic polymorphisms located in TGFB1, AGTR1, and VEGFA genes are associated to chronic renal allograft dysfunction
2012
2
10.1016/j.cyto.2012.02.017
Hussam Al-Kateb
Multiple variants in vascular endothelial growth factor (VEGFA) are risk factors for time to severe retinopathy in type 1 diabetes: the DCCT/EDIC genetics study.
2007
3
-
Martina Almasi
Association study of selected genetic polymorphisms and occurrence of venous thromboembolism in patients with multiple myeloma who were treated with thalidomide
2011
0
10.1016/j.clml.2011.03.024
I Immonen
Vascular endothelial growth factor gene variation and the response to photodynamic therapy in age-related macular degeneration
2010
2
http://dx.doi.org/10.1016/j.ophtha.2009.06.037
Ilkka Immonen
Vascular endothelial growth factor gene variation and the response to photodynamic therapy in age-related macular degeneration.
2010
8
10.1016/j.ophtha.2009.06.037
P J Hsiao
Vascular endothelial growth factor gene polymorphisms in thyroid cancer
2007
1
10.1677/JOE-07-0395
Ilkka Immonen
Vascular endothelial growth factor gene variation and the response to photodynamic therapy in age-related macular degeneration.
2010
6
-
Ning Song
Vascular endothelial growth factor (VEGF) -2578C/A and -460C/T gene polymorphisms and lung cancer risk: a meta-analysis involving 11 case-control studies.
2013
1
10.1007/s13277-013-1119-y
Un Chul Park
GENETIC FACTORS ASSOCIATED WITH RESPONSE TO INTRAVITREAL RANIBIZUMAB IN KOREAN PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.
2013
3
10.1097/IAE.0b013e3182979e1e
Yan Lu
Two Polymorphisms (Rs699947, Rs2010963) in the VEGFA Gene and Diabetic Retinopathy: An Updated Meta-Analysis
2012
1
10.4172/2155-6156.S3-006
Un Chul Park
Genetic factors associated with response to intravitreal Ranizumab in Korean patients with neovascular age-related macular degeneration
2013
1
10.1097/IAE.0b013e3182979e1e
Mario Scartozzi
Role of vascular endothelial growth factor (VEGF) and VEGF-R genotyping in guiding the metastatic process in pT4a resected gastric cancer patients
2012
2
10.1371/journal.pone.0038192
M L Martinez-Fierro
Positive association between vascular endothelial growth factor (VEGF) -2578 C/A variant and prostate cancer.
2013
3
10.3233/CBM-130348
Mario Scartozzi
Role of Vascular Endothelial Growth Factor (VEGF) and VEGF-R Genotyping in Guiding the Metastatic Process in pT4a Resected Gastric Cancer Patients
2012
2
10.1371/journal.pone.0038192
Evidence compiled by the
Personal Genome Project
There are no results from the
Personal Genome Project
yet. Please come back later.
Publications listed by
Genome.gov
There are no results from
genome.gov
yet. Please come back later.
Users who share this SNP:
Genome Browser