openSNP | rs3764880

Links to SNPedia

Title	Summary
rs3764880 A/A	1.2 - 1.8x increased tuberculosis risk
rs3764880 A/G	Possible 1.2 - 1.8x increased tuberculosis susceptibility in females
rs3764880 G/G	Normal

Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).

Publications on this SNP on the Public Library of Science:

First Author	Title	Year of Publication	# of readers
Jacques Fellay	Common Genetic Variation and the Control of HIV-1 in Humans	2009	20820
Olivier Neyrolles	Sexual Inequality in Tuberculosis	2009	31125
Grant R. Campbell	Toll-Like Receptor 8 Ligands Activate a Vitamin D Mediated Autophagic Response that Inhibits Human Immunodeficiency Virus Type 1	2012	8179
Marieke J. H. Coenen	Genetic Variants in Toll-Like Receptors Are Not Associated with Rheumatoid Arthritis Susceptibility or Anti-Tumour Necrosis Factor Treatment Outcome	2010	3740
Yun Deng	MicroRNA-3148 Modulates Allelic Expression of Toll-Like Receptor 7 Variant Associated with Systemic Lupus Erythematosus	2013	6554
Sonia Davila	Genetic Association and Expression Studies Indicate a Role of Toll-Like Receptor 8 in Pulmonary Tuberculosis	2008	12412
Haiko Schurz	TLR1, 2, 4, 6 and 9 Variants Associated with Tuberculosis Susceptibility: A Systematic Review and Meta-Analysis	2015	3338
Grant R. Campbell	Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration	2015	5825
Mark C. Dessing	Toll-Like Receptor Family Polymorphisms Are Associated with Primary Renal Diseases but Not with Renal Outcomes Following Kidney Transplantation	2015	1654
Sonia Davila	Genetic Association and Expression Studies Indicate a Role of Toll-Like Receptor 8 in Pulmonary Tuberculosis	2008	14107

Publications on this SNP on Mendeley

First Author	Title	Pub. Year	# of Readers	DOI
Nazan Dalgic	Relationship between toll-like receptor 8 gene polymorphisms and pediatric pulmonary tuberculosis.	2011	4	10.3233/DMA-2011-0800
Zhong Chen	Toll-like receptor 8 polymorphism and coronary artery disease.	2009	7	10.1007/s11033-008-9396-z
Zhong Chen	Toll-like receptor 8 polymorphism and coronary artery disease.	2009	5	-
Sonia Davila	Genetic Association and Expression Studies Indicate a Role of Toll-Like Receptor 8 in Pulmonary Tuberculosis	2008	38	10.1371/journal.pgen.1000218
Michael P Gantier	Genetic modulation of TLR8 response following bacterial phagocytosis.	2010	21	10.1002/humu.21321
Nazan Dalgic	Relationship between toll-like receptor 8 gene polymorphisms and pediatric pulmonary tuberculosis.	2011	1	-
Michael P Gantier	Genetic modulation of TLR8 response following bacterial phagocytosis.	2010	1	-
Jie Dai	Regulatory T cells and Toll-like receptors: What is the missing link?	2009	24	10.1016/j.intimp.2009.01.027
Sonia Davila	Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis.	2008	46	10.1371/journal.pgen.1000218
Jie Dai	Regulatory T cells and Toll-like receptors: what is the missing link?	2009	7	10.1016/j.intimp.2009.01.027
D-Y Oh	A functional toll-like receptor 8 variant is associated with HIV disease restriction.	2008	27	10.1086/590431
Qian Zhang	Polymorphisms of TLR7 and TLR8 associated with risk of asthma and asthma-related phenotypes in a southeastern Chinese Han population	2009	2	10.1016/S1007-4376(09)60022-8
Michael P Gantier	Genetic modulation of TLR8 response following bacterial phagocytosis.	2010	16	-
Masayuki Saruta	High-frequency haplotypes in the X chromosome locus TLR8 are associated with both CD and UC in females.	2009	8	10.1002/ibd.20754
Taube S Oh DY Hamouda O, Kücherer C, Poggensee G, Jessen H, Eckert JK, Neumann K, Storek A, Pouliot M, Borgeat P, Oh N, Schreier E, Pruss A, Hattermann K, Schumann RR.	A Functional Toll-Like Receptor 8 Variant Is Associated with HIV Disease Restriction.\r	2008	1
Qian Zhang	Polymorphisms of TLR7 and TLR8 associated with risk of asthma and asthma-related phenotypes in a southeastern Chinese Han population	2009	2	10.1016/S1007-4376(09)60022-8
J. Valverde	TLR7/8/9 polymorphisms and their associations in systemic lupus erythematosus patients from Southern Brazil	2012	10	10.1177/0961203311425522
Sonia Davila	Genetic association and expression studies indicate a role of Toll-like receptor 8 in pulmonary tuberculosis	2008	53	10.1371/journal.pgen.1000218
Kristin M Beima-Sofie	Toll-like receptor variants are associated with infant HIV-1 acquisition and peak plasma HIV-1 RNA level.	2013	5	10.1097/QAD.0b013e3283629117
D-Y Oh	A functional toll-like receptor 8 variant is associated with HIV disease restriction.	2008	20	-
Chiou-Huey Wang	Functional Polymorphisms of TLR8 Are Associated With Hepatitis C Virus Infection.	2013	1	10.1111/imm.12211

Evidence compiled by the Personal Genome Project

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Publications listed by Genome.gov

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Name	rs3764880
Chromosome	X
Position	12906707
Weight of evidence	56

SNP rs3764880

Basic Information

Genotype Frequency

Allele Frequency

Additional Information

Links to SNPedia

Publications on this SNP on the Public Library of Science:

Publications on this SNP on Mendeley

Evidence compiled by the Personal Genome Project

Publications listed by Genome.gov

Users who share this SNP:

Genome Browser

Contacts