openSNP | rs324420

Links to SNPedia

Title	Summary
rs324420 A/C	Normal
rs324420 A/A	Significantly increased risk for substance use disorders
rs324420 C/C	Normal

Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).

Publications on this SNP on the Public Library of Science:

First Author	Title	Year of Publication	# of readers
Pablo M. Rusjan	Voxel level quantification of [¹¹C]CURB, a radioligand for Fatty Acid Amide Hydrolase, using high resolution positron emission tomography	2018	126

Publications on this SNP on Mendeley

First Author	Title	Pub. Year	# of Readers	DOI
R. Bogdan	Genetic variation in endocannabinoid signaling moderates the association between childhood maltreatment and amygdala habituation	2012	1
Emmanuelle Durand	Evaluating the association of FAAH common gene variation with childhood, adult severe obesity and type 2 diabetes in the French population.	2008	3	-
Daniel Antonio De Luis	Effects of C358A missense polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase on weight loss after a hypocaloric diet.	2011	3	-
B S Wong	Randomized pharmacodynamic and pharmacogenetic trial of dronabinol effects on colon transit in irritable bowel syndrome-diarrhea.	2012	4	10.1111/j.1365-2982.2011.01874.x
Andrea M Dlugos	More aroused, less fatigued: fatty acid amide hydrolase gene polymorphisms influence acute response to amphetamine.	2010	10	10.1038/npp.2009.166
Dorit P Jensen	The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites.	2007	2	10.1007/s00109-006-0139-0
Joseph P Schacht	Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis.	2009	4	-
Heather M Haughey	Marijuana withdrawal and craving: influence of the cannabinoid receptor 1 (CNR1) and fatty acid amide hydrolase (FAAH) genes.	2008	13	-
Paula Tejera	Distinct and replicable genetic risk factors for acute respiratory distress syndrome of pulmonary or extrapulmonary origin.	2012	5	10.1136/jmedgenet-2012-100972
Daniel Antonio De Luis	Effects of C358A missense polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase on weight loss after a hypocaloric diet	2011	7	10.1016/j.metabol.2010.07.007
K P MacPherson	Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity	2012	21	10.1038/mp.2012.72
P Tejera	Distinct and replicable genetic risk factors for acute respiratory distress syndrome of pulmonary or extrapulmonary origin	2012	1	10.1136/jmedgenet-2012-100972
B S Wong	Randomized pharmacodynamic and pharmacogenetic trial of dronabinol effects on colon transit in irritable bowel syndrome-diarrhea.	2012	5	10.1111/j.1365-2982.2011.01874.x
Banny S. Wong	Pharmacogenetic trial of a cannabinoid agonist shows reduced fasting colonic motility in patients with nonconstipated irritable bowel syndrome	2011	10	10.1053/j.gastro.2011.07.036
Paula Tejera	Distinct and replicable genetic risk factors for acute respiratory distress syndrome of pulmonary or extrapulmonary origin.	2012	3	10.1136/jmedgenet-2012-100972
B S Wong	Randomized pharmacodynamic and pharmacogenetic trial of dronabinol effects on colon transit in irritable bowel syndrome-diarrhea.	2012	1	10.1111/j.1365-2982.2011.01874.x
B S Wong	Pharmacogenetic effects of dronabinol on colonic functions in irritable bowel syndrome	2011	1
M Storr	The role of fatty acid hydrolase gene variants in inflammatory bowel disease.	2009	4	-
O Gunduz-Cinar	Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity.	2012	42	10.1038/mp.2012.72
Timo D Müller	Mutation screen and association studies for the fatty acid amide hydrolase (FAAH) gene and early onset and adult obesity	2010	9	10.1186/1471-2350-11-2
N Knoll	The Fatty Acid Amide Hydrolase (FAAH) Gene Variant rs324420 AA/AC is not Associated with Weight Loss in a 1-Year Lifestyle Intervention for Obese Children and Adolescents	2012	4	10.1055/s-0031-1291306
N. Knoll	The Fatty Acid Amide Hydrolase (FAAH) Gene Variant rs324420 AA/AC is not Associated with Weight Loss in a 1-Year Lifestyle Intervention for Obese Children and Adolescents	2012	5	10.1055/s-0031-1291306
Dorit P Jensen	The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites.	2007	1	-
Joseph P Schacht	Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis.	2009	10	10.1007/s00213-008-1397-z
P Tejera	Distinct and replicable genetic risk factors for acute respiratory distress syndrome of pulmonary or extrapulmonary origin	2012	2	10.1136/jmedgenet-2012-100972\rjmedgenet-2012-100972 [pii]
N. Knoll	The fatty acid amide hydrolase (FAAH) gene variant rs324420 AA/AC is not associated with weight loss in a 1-year lifestyle intervention for obese children and adolescents	2012	5	10.1055/s-0031-1291306
M Storr	The role of fatty acid hydrolase gene variants in inflammatory bowel disease.	2009	6	10.1111/j.1365-2036.2008.03910.x
Daniel Antonio de Luis	Effects of C358A missense polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase on weight loss after a hypocaloric diet.	2011	5	10.1016/j.soard.2010.01.005

Evidence compiled by the Personal Genome Project

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Publications listed by Genome.gov

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Name	rs324420
Chromosome	1
Position	46405089
Weight of evidence	45

SNP rs324420

Basic Information

Genotype Frequency

Allele Frequency

Additional Information

Links to SNPedia

Publications on this SNP on the Public Library of Science:

Publications on this SNP on Mendeley

Evidence compiled by the Personal Genome Project

Publications listed by Genome.gov

Users who share this SNP:

Genome Browser

Contacts