openSNP
Toggle
News
Data
SNPs
Genotypes
Phenotypes
Phenotypes Pictures
Open Humans Connections
Latest Data
About
About Us
Statistics
FAQ
Sign In
x
It seems like you have JavaScript disabled. This will make some features of openSNP.org, like the drop-down menus, break.
SNP rs3087456
Basic Information
Name
rs3087456
Chromosome
16
Position
10877045
Weight of evidence
41
Genotype Frequency
Allele Frequency
Additional Information
SNPedia (1)
PLoS (3)
Mendeley (30)
Personal Genome Project (0)
Genome.gov (0)
Other users (1708)
Comments (0)
Links to SNPedia
Title
Summary
rs3087456 G/A
No summary provided.
Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).
Publications on this SNP on the Public Library of Science:
First Author
Title
Year of Publication
# of readers
Marcus Ronninger
Interaction Analysis between
HLA-DRB1
Shared Epitope Alleles and MHC Class II Transactivator
CIITA
Gene with Regard to Risk of Rheumatoid Arthritis
2012
3290
Maria Swanberg
Polymorphisms in the Inflammatory Genes
CIITA
,
CLEC16A
and
IFNG
Influence BMD, Bone Loss and Fracture in Elderly Women
2012
3088
Eero Lindholm
Polymorphism in the
MHC2TA
Gene Is Associated with Features of the Metabolic Syndrome and Cardiovascular Mortality
2006
7756
Publications on this SNP on Mendeley
First Author
Title
Pub. Year
# of Readers
DOI
Stephen Eyre
Investigation of the MHC2TA gene, associated with rheumatoid arthritis in a Swedish population, in a UK rheumatoid arthritis cohort.
2006
3
-
Ryan Ramanujam
Lack of association of the CIITA -168A→G promoter SNP with myasthenia gravis and its role in autoimmunity.
2010
10
10.1186/1471-2350-11-147
M C Eike
CIITA gene variants are associated with rheumatoid arthritis in Scandinavian populations.
2012
6
10.1038/gene.2012.11
Maria Swanberg
Polymorphisms in the Inflammatory Genes CIITA, CLEC16A and IFNG Influence BMD, Bone Loss and Fracture in Elderly Women.
2012
5
10.1371/journal.pone.0047964
P G Bronson
The MHC2TA -168A/G polymorphism and risk for rheumatoid arthritis: a meta-analysis of 6861 patients and 9270 controls reveals no evidence for association.
2008
2
10.1136/ard.2007.077099
M V Prasad Linga-Reddy
A polymorphic variant in the MHC2TA gene is not associated with systemic lupus erythematosus.
2007
3
10.1111/j.1399-0039.2007.00920.x
M C Eike
CIITA gene variants are associated with rheumatoid arthritis in Scandinavian populations
2012
1
gene201211 [pii]\r10.1038/gene.2012.11
A Carlsson
Age-dependent variation of genotypes in MHC II transactivator gene (CIITA) in controls and association to type 1 diabetes
2012
4
10.1038/gene.2012.44
Mehran Ghaderi
MHC2TA single nucleotide polymorphism and genetic risk for autoimmune adrenal insufficiency.
2006
3
-
J Grunewald
Major histocompatibility complex class II transactivator gene polymorphism: associations with Löfgren's syndrome.
2010
1
10.1111/j.1399-0039.2010.01476.x
D A Akkad
Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups.
2006
4
-
P Harrison
MHC2TA promoter polymorphism (-168*G/A, rs3087456) is not associated with susceptibility to rheumatoid arthritis in British Caucasian rheumatoid arthritis patients.
2007
2
10.1093/rheumatology/kel300
D A Akkad
Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups.
2006
4
10.1111/j.1744-313X.2006.00568.x
M C Eike
CIITA gene variants are associated with rheumatoid arthritis in Scandinavian populations
2012
4
10.1038/gene.2012.11;
Stephen Eyre
Investigation of the MHC2TA gene, associated with rheumatoid arthritis in a Swedish population, in a UK rheumatoid arthritis cohort.
2006
5
10.1002/art.22166
B Dema
Autoimmune disease association signals in CIITA and KIAA0350 are not involved in celiac disease susceptibility.
2009
2
-
M C Eike
CIITA gene variants are associated with rheumatoid arthritis in Scandinavian populations.
2012
1
10.1038/gene.2012.11
Bruno Zagonel Piovezan
Both qualitative and quantitative genetic variation of MHC class II molecules may influence susceptibility to autoimmune diseases: the case of endemic pemphigus foliaceus
2013
1
10.1016/j.humimm.2013.06.008
P Harrison
MHC2TA promoter polymorphism (-168*G/A, rs3087456) is not associated with susceptibility to rheumatoid arthritis in British Caucasian rheumatoid arthritis patients.
2007
2
-
Nina A. Daha
Interaction Analysis between HLA-DRB1 Shared Epitope Alleles and MHC Class II Transactivator CIITA Gene with Regard to Risk of Rheumatoid Arthritis
2012
8
10.1371/journal.pone.0032861
J Grunewald
Major histocompatibility complex class II transactivator gene polymorphism: associations with Lofgren's syndrome
2010
1
TAN1476 [pii]\r10.1111/j.1399-0039.2010.01476.x
M Garcia-Bermudez
Influence of MHCIITA rs3087456 and rs4774 polymorphisms in the susceptibility to cardiovascular disease of patients with rheumatoid arthritis.
2012
3
-
Mehran Ghaderi
MHC2TA single nucleotide polymorphism and genetic risk for autoimmune adrenal insufficiency.
2006
4
10.1210/jc.2006-0855
M V Prasad Linga-Reddy
A polymorphic variant in the MHC2TA gene is not associated with systemic lupus erythematosus.
2007
3
-
P G Bronson
The MHC2TA -168A/G polymorphism and risk for rheumatoid arthritis: a meta-analysis of 6861 patients and 9270 controls reveals no evidence for association.
2008
1
-
Kaisa K. Ivaska
Polymorphisms in the Inflammatory Genes CIITA, CLEC16A and IFNG Influence BMD, Bone Loss and Fracture in Elderly Women
2012
7
10.1371/journal.pone.0047964
J Grunewald
Major histocompatibility complex class II transactivator gene polymorphism: associations with Löfgren's syndrome.
2010
2
-
M C Eike
CIITA gene variants are associated with rheumatoid arthritis in Scandinavian populations.
2012
10
10.1038/gene.2012.11
Ryan Ramanujam
Lack of association of the CIITA -168A→G promoter SNP with myasthenia gravis and its role in autoimmunity
2010
9
10.1186/1471-2350-11-147
Marcus Ronninger
Interaction Analysis between HLA-DRB1 Shared Epitope Alleles and MHC Class II Transactivator CIITA Gene with Regard to Risk of Rheumatoid Arthritis.
2012
7
10.1371/journal.pone.0032861
Evidence compiled by the
Personal Genome Project
There are no results from the
Personal Genome Project
yet. Please come back later.
Publications listed by
Genome.gov
There are no results from
genome.gov
yet. Please come back later.
Users who share this SNP:
Genome Browser