openSNP | rs266729

Links to SNPedia

Title	Summary
rs266729 C/G	0.73x decreased risk for colorectal cancer
rs266729 G/G	0.73x decreased risk for colorectal cancer
rs266729 C/C	Normal

Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).

Publications on this SNP on the Public Library of Science:

First Author	Title	Year of Publication	# of readers
Andrew Mente	Causal Relationship between Adiponectin and Metabolic Traits: A Mendelian Randomization Study in a Multiethnic Population	2013	2136
Hong Yang	Adiponectin Gene Polymorphism rs2241766 T/G Is Associated with Response to Pioglitazone Treatment in Type 2 Diabetic Patients from Southern China	2014	1023
J. Brent Richards	A Genome-Wide Association Study Reveals Variants in ARL15 that Influence Adiponectin Levels	2009	12676
Amy M. Ahasic	Adiponectin Gene Polymorphisms and Acute Respiratory Distress Syndrome Susceptibility and Mortality	2014	1929
Margrit Urbanek	The Role of Inflammatory Pathway Genetic Variation on Maternal Metabolic Phenotypes during Pregnancy	2012	4645
Meng Gao	Association of Genetic Variants in the Adiponectin Gene with Metabolic Syndrome: A Case-Control Study and a Systematic Meta-Analysis in the Chinese Population	2013	2815
Yan-yan Li	Adiponectin-11377CG Gene Polymorphism and Type 2 Diabetes Mellitus in the Chinese Population: A Meta-Analysis of 6425 Subjects	2013	2722
Ilana Blech	Predicting Diabetic Nephropathy Using a Multifactorial Genetic Model	2011	4643
Zhuling Yu	Relationship between Adiponectin Gene Polymorphisms and Late-Onset Alzheimer’s Disease	2015	1503
Ching-Jung Hsieh	Association of Adiponectin Gene Polymorphism with Nonalcoholic Fatty Liver Disease in Taiwanese Patients with Type 2 Diabetes	2015	2305
Yingfu Li	The Association of Adiponectin Gene Promoter Variations with Non-Small Cell Lung Cancer in a Han Chinese Population	2015	1338

Publications on this SNP on Mendeley

First Author	Title	Pub. Year	# of Readers	DOI
Makoto Saito	Association of adiponectin polymorphism with cord blood adiponectin concentrations and intrauterine growth.	2011	4	10.1038/jhg.2011.134
SL Prior	Association between the adiponectin promoter rs266729 gene variant and oxidative stress in patients with diabetes mellitus	2009	0
Raya Zyadine	Genetic association of adiponectin with type 2 diabetes in Jordanian Arab population	2012	2	10.1016/j.gene.2012.09.095
Harvest F. Gu	SOX2 has gender-specific genetic effects on diabetic nephropathy in samples from patients with type 1 diabetes mellitus in the GoKinD study	2009	6	10.1016/j.genm.2009.11.001
Dongying Zhang	Effects of MCF2L2, ADIPOQ and SOX2 genetic polymorphisms on the development of nephropathy in type 1 Diabetes Mellitus.	2010	11	10.1186/1471-2350-11-116
Jane F Ferguson	Gene-nutrient interactions in the metabolic syndrome: single nucleotide polymorphisms in ADIPOQ and ADIPOR1 interact with plasma saturated fatty acids to modulate insulin resistance.	2010	22	10.3945/ajcn.2009.28255
Haiyan Chu	AdipoQ polymorphisms are associated with type 2 diabetes mellitus: a meta-analysis study.	2013	3	10.1002/dmrr.2424
Asem Alkhateeb	Genetic association of adiponectin with type 2 diabetes in Jordanian Arab population	2013	4	10.1016/j.gene.2012.09.095
M. Gong	Association of the ADIPOQ rs17360539 and rs266729 polymorphisms with type 2 diabetes: A meta-analysis	2010	7	10.1016/j.mce.2010.05.007
Dongying Zhang	Effects of MCF2L2, ADIPOQ and SOX2 genetic polymorphisms on the development of nephropathy in type 1 Diabetes Mellitus	2010	0	10.1186/1471-2350-11-116
J F Ferguson	Gene-nutrient interactions in the metabolic syndrome: single nucleotide polymorphisms in ADIPOQ and ADIPOR1 interact with plasma saturated fatty acids to modulate insulin resistance	2009	0
Hsiao T J	A common variant in the adiponectin gene on weight loss and body composition under sibutramine therapy in obesity	2010	0	10.2147/CPAA.S8657
Eugene Lin	A common variant in the adiponectin gene on weight loss and body composition under sibutramine therapy in obesity	2010	4	10.2147/CPAA.S8657
M Gong	Association of the ADIPOQ rs17360539 and rs266729 polymorphisms with type 2 diabetes: a meta-analysis.	2010	7	10.1016/j.mce.2010.05.007
B Y Gueuvoghlanian-Silva	Profile of Inflammatory Mediators in Gestational Diabetes Mellitus: Phenotype and Genotype	2012	2
F. Zadjali	Association of adiponectin promoter variants with traits and clusters of metabolic syndrome in Arabs: Family-based study	2013	3	10.1016/j.gene.2013.06.057
Sarah L. Prior	Association of the adiponectin rs266729 C>G variant and coronary heart disease in the low risk 'Golden Years' type 1 diabetes cohort	2011	2	10.1016/j.diabres.2010.12.007
A Alkhateeb	Genetic association of adiponectin with type 2 diabetes in Jordanian Arab population	2013	0	10.1016/j.gene.2012.09.095
Sarah L Prior	Association between the adiponectin promoter rs266729 gene variant and oxidative stress in patients with diabetes mellitus.	2009	4	ehp090 [pii]\r10.1093/eurheartj/ehp090
Andrew Mente	Causal Relationship between Adiponectin and Metabolic Traits: A Mendelian Randomization Study in a Multiethnic Population.	2013	1	10.1371/journal.pone.0066808
M C Gornick	Adiponectin gene and risk of colorectal cancer.	2011	1	10.1038/bjc.2011.259
Luis G Carvajal-Carmona	Common variation at the adiponectin locus is not associated with colorectal cancer risk in the UK.	2009	0
Luis G Carvajal-Carmona	Common variation at the adiponectin locus is not associated with colorectal cancer risk in the UK.	2009	10	10.1093/hmg/ddp109
Andrew Mente	Causal Relationship between Adiponectin and Metabolic Traits: A Mendelian Randomization Study in a Multiethnic Population	2013	6	10.1371/journal.pone.0066808
Yanrui Wu	Polymorphisms in PPARD, PPARG and APM1 associated with four types of Traditional Chinese Medicine constitutions	2010	7	10.1016/S1673-8527(09)60055-2
Xizhen Wang	APM1 gene variants -11377C/G and 4545G/C are associated respectively with obesity and with non-obesity in Chinese type 2 diabetes.	2009	0
Xizhen Wang	APM1 gene variants -11377C/G and 4545G/C are associated respectively with obesity and with non-obesity in Chinese type 2 diabetes	2009	5	10.1016/j.diabres.2009.03.004
Kandaswamy Ramya	Genetic association of ADIPOQ gene variants with type 2 diabetes, obesity and serum adiponectin levels in south Indian population	2013	4	10.1016/j.gene.2013.09.012
M Gong	Association of the ADIPOQ rs17360539 and rs266729 polymorphisms with type 2 diabetes: a meta-analysis.	2010	0
I M Ibrahim	Common variation in the adiponectin gene has an effect on systolic blood pressure	2011	2	10.1038/jhh.2010.122
M C Gornick	Adiponectin gene and risk of colorectal cancer.	2011	0	10.1038/bjc.2011.259
Guoxin Tong	Common variants in adiponectin gene are associated with coronary artery disease and angiographical severity of coronary atherosclerosis in type 2 diabetes.	2013	6	10.1186/1475-2840-12-67
P Henson	The presence of single-stranded regions in mammalian DNA.	1978	0

Evidence compiled by the Personal Genome Project

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Publications listed by Genome.gov

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Name	rs266729
Chromosome	3
Position	186841685
Weight of evidence	70

SNP rs266729

Basic Information

Genotype Frequency

Allele Frequency

Additional Information

Links to SNPedia

Publications on this SNP on the Public Library of Science:

Publications on this SNP on Mendeley

Evidence compiled by the Personal Genome Project

Publications listed by Genome.gov

Users who share this SNP:

Genome Browser

Contacts