openSNP | rs2230926

Links to SNPedia

Title	Summary
rs2230926 G/G	1.4x risk of rheumatoid arthritis
rs2230926 T/T	Common in complete genomics
rs2230926 G/T	1.4x higher risk for rheumatoid arthritis

Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).

Publications on this SNP on the Public Library of Science:

First Author	Title	Year of Publication	# of readers
Keisuke Kadota	Analysis of Gender Differences in Genetic Risk: Association of TNFAIP3 Polymorphism with Male Childhood-Onset Systemic Lupus Erythematosus in the Japanese Population	2013	2381
Wanling Yang	Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus	2010	14334
Hirofumi Nakaoka	A Systems Genetics Approach Provides a Bridge from Discovered Genetic Variants to Biological Pathways in Rheumatoid Arthritis	2011	5888
Shaofeng Wang	An Enhancer Element Harboring Variants Associated with Systemic Lupus Erythematosus Engages the TNFAIP3 Promoter to Influence A20 Expression	2013	8246
Rohina Rubicz	A Genome-Wide Integrative Genomic Study Localizes Genetic Factors Influencing Antibodies against Epstein-Barr Virus Nuclear Antigen 1 (EBNA-1)	2013	9845
Elisa Alonso-Perez	Further Evidence of Subphenotype Association with Systemic Lupus Erythematosus Susceptibility Loci: A European Cases Only Study	2012	3326
Yugang Liu	Functional Effect of Polymorphisms in the Promoter of TNFAIP3 (A20) in Acute Pancreatitis in the Han Chinese Population	2014	958
Si Chen	Genetic Association Study of TNFAIP3, IFIH1, IRF5 Polymorphisms with Polymyositis/Dermatomyositis in Chinese Han Population	2014	1887
Yukinori Okada	A Genome-Wide Association Study Identified AFF1 as a Susceptibility Locus for Systemic Lupus Eyrthematosus in Japanese	2012	7654
Taku Suzuki	PADI4 and HLA-DRB1 Are Genetic Risks for Radiographic Progression in RA Patients, Independent of ACPA Status: Results from the IORRA Cohort Study	2013	3906

Publications on this SNP on Mendeley

First Author	Title	Pub. Year	# of Readers	DOI
G. Nocturne	Germline and somatic genetic variations of TNFAIP3 in lymphoma complicating primary Sjogren's syndrome	2013	2	10.1182/blood-2013-05-503383
Eugénie Koumakis	Brief report: candidate gene study in systemic sclerosis identifies a rare and functional variant of the TNFAIP3 locus as a risk factor for polyautoimmunity.	2012	2	10.1002/art.34490
T Tejasvi	TNFAIP3 polymorphisms and age at onset are associated with response to tumour necrosis factor blockade in psoriasis	2011	6
Kenichi Shimane	The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.	2010	5	-
Trilokraj Tejasvi	TNFAIP3 Gene Polymorphisms Are Associated with Response to TNF Blockade in Psoriasis	2012	11	10.1038/jid.2011.376
Aya Kawasaki	Association of TNFAIP3 polymorphism with susceptibility to systemic lupus erythematosus in a Japanese population.	2010	0	10.1155/2010/207578
M Jani	Investigation of idiopathic inflammatory myopathy for shared genetic risk factors with other autoimmune disorders	2012	2	-
Aya Kawasaki	Association of TNFAIP3 Polymorphism with Susceptibility to Systemic Lupus Erythematosus in a Japanese Population	2010	1	10.1155/2010/207578
S L Musone	Sequencing of TNFAIP3 and association of variants with multiple autoimmune diseases.	2011	7	10.1038/gene.2010.64
Li-Qiong Cai	A single-nucleotide polymorphism of the TNFAIP3 gene is associated with systemic lupus erythematosus in Chinese Han population.	2010	2	-
Han Cen	Genetic interaction between genes involved in NF-κB signaling pathway in systemic lupus erythematosus.	2013	1	10.1016/j.molimm.2013.07.006
Kenichi Shimane	The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.	2010	6	10.1002/art.27190
Aya Kawasaki	Association of TNFAIP3 polymorphism with susceptibility to systemic lupus erythematosus in a Japanese population	2010	0	10.1155/2010/207578
S L Musone	Sequencing of TNFAIP3 and association of variants with multiple autoimmune diseases.	2011	5	-
Stacy L Musone	Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus.	2008	17	-
Stacy L Musone	Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus.	2008	21	10.1038/ng.202
Li-Qiong Cai	A single-nucleotide polymorphism of the TNFAIP3 gene is associated with systemic lupus erythematosus in Chinese Han population.	2010	2	10.1007/s11033-009-9818-6
Gaetane Nocturne	Germline and somatic genetic variations of TNFAIP3 in lymphoma complicating primary Sjogren's syndrome.	2013	7	10.1182/blood-2013-05-503383

Evidence compiled by the Personal Genome Project

There are no results from the Personal Genome Project yet. Please come back later.

Publications listed by Genome.gov

First Author	Title	Journal	Publication Date	Trait	p-value	Confidence Interval
Han JW	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Nat Genet	10/18/2009	Systemic lupus erythematosus	1.0e-17	[1.52-1.94]

Name	rs2230926
Chromosome	6
Position	137874929
Weight of evidence	55

SNP rs2230926

Basic Information

Genotype Frequency

Allele Frequency

Additional Information

Links to SNPedia

Publications on this SNP on the Public Library of Science:

Publications on this SNP on Mendeley

Evidence compiled by the Personal Genome Project

Publications listed by Genome.gov

Users who share this SNP:

Genome Browser

Contacts