openSNP | rs1801282

Links to SNPedia

Title	Summary
rs1801282 G/G	Watch out for high fat in diet
rs1801282 C/G	Watch out for high fat in diet
rs1801282 C/C	Normal fat metabolism; common in clinvar

Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).

Publications on this SNP on the Public Library of Science:

First Author	Title	Year of Publication	# of readers
Angela M Hancock	Adaptations to Climate in Candidate Genes for Common Metabolic Disorders	2008	24524
Ilana Blech	Predicting Diabetic Nephropathy Using a Multifactorial Genetic Model	2011	4643
Hongyan Mao	Meta-Analysis of the Relationship between Common Type 2 Diabetes Risk Gene Variants with Gestational Diabetes Mellitus	2012	7343
Li-Jun Tan	Replication of 6 Obesity Genes in a Meta-Analysis of Genome-Wide Association Studies from Diverse Ancestries	2014	4826
Slavica Pecioska	Association between Type 2 Diabetes Loci and Measures of Fatness	2010	16908
Shi-Heng Wang	Inference of Cross-Level Interaction between Genes and Contextual Factors in a Matched Case-Control Metabolic Syndrome Study: A Bayesian Approach	2013	1039
Anders Borglykke	Genetic Variant SCL2A2 Is Associated with Risk of Cardiovascular Disease – Assessing the Individual and Cumulative Effect of 46 Type 2 Diabetes Related Genetic Variants	2012	2487
Desmond D. Campbell	Amerind Ancestry, Socioeconomic Status and the Genetics of Type 2 Diabetes in a Colombian Population	2012	5756
Xiao Ou Shu	Identification of New Genetic Risk Variants for Type 2 Diabetes	2010	12815
Hanxiang Gao	Genome-Wide Linkage Scan Identifies Two Novel Genetic Loci for Coronary Artery Disease: In GeneQuest Families	2014	1159
John R. B. Perry	Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases	2012	19233
Christopher G. Bell	Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus	2010	20501
Steffen Bank	Polymorphisms in the Inflammatory Pathway Genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG Are Associated with Susceptibility of Inflammatory Bowel Disease in a Danish Cohort	2014	5137
Yuan-Pin Hung	Effects of PPARγ and RBP4 Gene Variants on Metabolic Syndrome in HIV-Infected Patients with Anti-Retroviral Therapy	2012	2368
Claudia Langenberg	Gene-Lifestyle Interaction and Type 2 Diabetes: The EPIC InterAct Case-Cohort Study	2014	20508
Juan L. Rodriguez-Flores	Exome Sequencing of Only Seven Qataris Identifies Potentially Deleterious Variants in the Qatari Population	2012	3672
Kevin M. Waters	Consistent Association of Type 2 Diabetes Risk Variants Found in Europeans in Diverse Racial and Ethnic Groups	2010	10269
Steven Haney	RNAi Screening in Primary Human Hepatocytes of Genes Implicated in Genome-Wide Association Studies for Roles in Type 2 Diabetes Identifies Roles for CAMK1D and CDKAL1, among Others, in Hepatic Glucose Regulation	2013	4518
Michelle A. T. Hildebrandt	Genetic Variants in Inflammation-Related Genes Are Associated with Radiation-Induced Toxicity Following Treatment for Non-Small Cell Lung Cancer	2010	6708
John P.A. Ioannidis	Heterogeneity in Meta-Analyses of Genome-Wide Association Investigations	2007	10623
Vipin Gupta	Association Study of 25 Type 2 Diabetes Related Loci with Measures of Obesity in Indian Sib Pairs	2013	3049
Jie Wen	Investigation of Type 2 Diabetes Risk Alleles Support CDKN2A/B, CDKAL1, and TCF7L2 As Susceptibility Genes in a Han Chinese Cohort	2010	6722
Bin Cui	A Genome-Wide Association Study Confirms Previously Reported Loci for Type 2 Diabetes in Han Chinese	2011	5065
Neelam Hassanali	Evaluation of Common Type 2 Diabetes Risk Variants in a South Asian Population of Sri Lankan Descent	2014	2404
Wenjing Ou	Association of CVD Candidate Gene Polymorphisms with Ischemic Stroke and Cerebral Hemorrhage in Chinese Individuals	2014	2033
Badri Padhukasahasram	Presymptomatic Risk Assessment for Chronic Non-Communicable Diseases	2010	9456
Yudi Pawitan	How Many Genetic Variants Remain to Be Discovered?	2009	4574
André Gustavo P. Sousa	Genetic Variants of Diabetes Risk and Incident Cardiovascular Events in Chronic Coronary Artery Disease	2011	2482
Cheng Hu	PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 Are Associated with Type 2 Diabetes in a Chinese Population	2009	8909
Agnieszka Maciejewska-Karlowska	Association between the Pro12Ala Polymorphism of the Peroxisome Proliferator-Activated Receptor Gamma Gene and Strength Athlete Status	2013	2437
Christiane Winkler	Lack of Association of Type 2 Diabetes Susceptibility Genotypes and Body Weight on the Development of Islet Autoimmunity and Type 1 Diabetes	2012	3098
Anshika Srivastava	Multi-Analytic Approach Elucidates Significant Role of Hormonal and Hepatocanalicular Transporter Genetic Variants in Gallstone Disease in North Indian Population	2013	2719
Xiaomu Kong	Association of Genetic Variants with Isolated Fasting Hyperglycaemia and Isolated Postprandial Hyperglycaemia in a Han Chinese Population	2013	3152
Valeriya Lyssenko	Genetic Prediction of Future Type 2 Diabetes	2005	21435
Min Xu	Combined Effects of 19 Common Variations on Type 2 Diabetes in Chinese: Results from Two Community-Based Studies	2010	5222
Lyudmyla Kedenko	Genetic Polymorphisms of the Main Transcription Factors for Adiponectin Gene Promoter in Regulation of Adiponectin Levels: Association Analysis in Three European Cohorts	2012	3959
Linda M. Dong	An Analysis of Growth, Differentiation and Apoptosis Genes with Risk of Renal Cancer	2009	4015
Sven Knüppel	Evaluation of 41 Candidate Gene Variants for Obesity in the EPIC-Potsdam Cohort by Multi-Locus Stepwise Regression	2013	3216
Qi Zhao	Cross-Sectional and Longitudinal Replication Analyses of Genome-Wide Association Loci of Type 2 Diabetes in Han Chinese	2014	2631
Guillaume Paré	Novel Association of HK1 with Glycated Hemoglobin in a Non-Diabetic Population: A Genome-Wide Evaluation of 14,618 Participants in the Women's Genome Health Study	2008	6594
Xia Wang	The Association between the Pro12Ala Variant in the PPARγ2 Gene and Type 2 Diabetes Mellitus and Obesity in a Chinese Population	2013	1853
Ming-Wei Su	Gene-Gene and Gene-Environmental Interactions of Childhood Asthma: A Multifactor Dimension Reduction Approach	2012	7101
Birgit-Christiane Zyriax	The Association of Genetic Markers for Type 2 Diabetes with Prediabetic Status - Cross-Sectional Data of a Diabetes Prevention Trial	2013	4027
Marie Louise Max Andersen	Complex Multi-Block Analysis Identifies New Immunologic and Genetic Disease Progression Patterns Associated with the Residual β-Cell Function 1 Year after Diagnosis of Type 1 Diabetes	2013	2989
Thomas Yates	Effect of the PPARG2 Pro12Ala Polymorphism on Associations of Physical Activity and Sedentary Time with Markers of Insulin Sensitivity in Those with an Elevated Risk of Type 2 Diabetes	2015	844
Maria A. Matuszek	Increased Insulin following an Oral Glucose Load, Genetic Variation near the Melatonin Receptor MTNR1B, but No Biochemical Evidence of Endothelial Dysfunction in Young Asian Men and Women	2015	1455
Xiaomu Kong	The Association of Type 2 Diabetes Loci Identified in Genome-Wide Association Studies with Metabolic Syndrome and Its Components in a Chinese Population with Type 2 Diabetes	2015	2999
Sofus C. Larsen	Association between Maternal Fish Consumption and Gestational Weight Gain: Influence of Molecular Genetic Predisposition to Obesity	2016	1924
Katherine Angela Benson	A HuGE Review and Meta-Analyses of Genetic Associations in New Onset Diabetes after Kidney Transplantation	2016	2223

Publications on this SNP on Mendeley

First Author	Title	Pub. Year	# of Readers	DOI
Cosmo S D	The PPAR2 P12A polymorphism predicts incident microalbuminuria in patients with type 2 diabetes: Evidence from the bergamo nephrologic diabetes complications trial (benedict)	2009	1	-
Wendy Johnson	PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diabetes.	2008	6	10.1016/j.neurobiolaging.2006.09.010
Tamer Bego	Association of PPARG and LPIN1 gene polymorphisms with metabolic syndrome and type 2 diabetes.	2011	0
D Campa	Association of a common polymorphism in the cyclooxygenase 2 gene with risk of non-small cell lung cancer	2004	5	10.1093/carcin/bgh008
Fatemeh Namvaran	Polymorphism of peroxisome proliferator-activated receptor ?? (PPAR??) Pro12Ala in the Iranian population: Relation with insulin resistance and response to treatment with pioglitazone in type 2 diabetes	2011	6	10.1016/j.ejphar.2011.09.158
Alena Stancáková	Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.	2009	18	10.2337/db09-0117
Matthias Folwaczny	Variants of the human PPARG locus and the susceptibility to chronic periodontitis.	2011	1	-
Jakub J Regieli	PPAR gamma variant influences angiographic outcome and 10-year cardiovascular risk in male symptomatic coronary artery disease patients.	2009	3	10.2337/dc08-1819
Salvatore De Cosmo	Impact of the PPAR-gamma2 Pro12Ala polymorphism and ACE inhibitor therapy on new-onset microalbuminuria in type 2 diabetes: evidence from BENEDICT.	2009	10	10.2337/db09-0407
Tuomas O Kilpeläinen	SNPs in PPARG associate with type 2 diabetes and interact with physical activity.	2008	11	10.1249/mss.0b013e318159d1cd
L Chen	Effect of the peroxisome proliferators-activated receptor (PPAR) gamma 3 gene on BMI in 1,210 school students from Morelos, Mexico	2006	4	-
Caiyan Wang	Quantitative assessment of the influence of PPARG P12A polymorphism on gestational diabetes mellitus risk.	2013	0	10.1007/s11033-012-2119-5
Rotraut Mössner	Variations in the peroxisome proliferator-activated receptor-gamma gene and melanoma risk.	2007	4	10.1016/j.canlet.2006.02.022
A AlSaleh	Interaction of PPARG Pro12Ala with dietary fat influences plasma lipids in subjects at cardiometabolic risk	2011	1	-
Christopher Butt	PPAR-gamma gene polymorphisms and psoriatic arthritis.	2006	2	-
D Campa	Association of a common polymorphism in the cyclooxygenase 2 gene with risk of non-small cell lung cancer	2004	3	10.1093/carcin/bgh008
J S Ho	Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart disease in a Hong Kong Chinese population	2012	1	10.1016/j.diabres.2012.03.012
Yiting Wang	Nested case-control study of energy regulation candidate gene single nucleotide polymorphisms and breast cancer.	2007	2	-
Hebe N Gouda	The Association Between the Peroxisome Proliferator-Activated Receptor-γ2 (PPARG2) Pro12Ala Gene Variant and Type 2 Diabetes Mellitus: A HuGE Review and Meta-Analysis	2010	24	10.1093/aje/kwp450
Fang Wang	Effect of genetic variants in KCNJ11, ABCC8, PPARG and HNF4A loci on the susceptibility of type 2 diabetes in Chinese Han population.	2009	5
Jorge Duran-Gonzalez	Association study of candidate gene polymorphisms and obesity in a young Mexican-American population from South Texas.	2011	1	-
Yujun Wang	Quantitative evaluation of common polymorphism (rs1801282) in the PPARγ2 gene and hypertension susceptibility.	2012	1	10.1016/j.gene.2012.04.035
Paul M Ridker	Alanine for proline substitution in the peroxisome proliferator-activated receptor gamma-2 (PPARG2) gene and the risk of incident myocardial infarction.	2003	6	10.1161/01.ATV.0000068680.19521.34
N Mtiraoui	Contribution of common variants of ENPP1, IGF2BP2, KCNJ11, MLXIPL, PPAR(gamma), SLC30A8 and TCF7L2 to the risk of type 2 diabetes in Lebanese and Tunisian Arabs	2012	5	-
Saidan Ding	The meta-analysis of the association of PPARG P12A, C161T polymorphism and coronary heart disease.	2012	2	10.1007/s00508-012-0223-0
Q Pei	PPAR-gamma 2 and PTPRD gene polymorphisms influence type 2 diabetes patients' response to pioglitazone in China	2013	1	Doi 10.1038/Aps.2012.144
Caiyan Wang	Quantitative assessment of the influence of PPARG P12A polymorphism on gestational diabetes mellitus risk	2012	2	10.1007/s11033-012-2119-5
Y Wang	Nested case-control study of energy regulation candidate gene single nucleotide polymorphisms and breast cancer	2007	4	-
K Zhou	PPARg but not FTO variants influence glycaemic response to metformin: A Go DARTS study	2010	1
M Rossbauer	Influence of type 2 associated polymorphisms on weight development in offspring of mothers with gestational diabetes	2011	1
Y M Cho	Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population.	2009	12	-
Salvatore De Cosmo	Impact of the PPAR-gamma2 Pro12Ala polymorphism and ACE inhibitor therapy on new-onset microalbuminuria in type 2 diabetes: evidence from BENEDICT	2009	0	-
Samir Ben Ali	Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma-2 gene on obesity risk and leptin levels in a Tunisian population.	2009	6	-
Eun-Jung Rhee	The association of Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma gene with serum osteoprotegerin levels in healthy Korean women.	2007	5	200712313 [pii]
Szilard Poliska	Association of peroxisome proliferator-activated receptor gamma polymorphisms with inflammatory bowel disease in a Hungarian cohort.	2012	2	10.1002/ibd.21798
Saidan Ding	The meta-analysis of the association of PPARG P12A, C161T polymorphism and coronary heart disease.	2012	2	10.1007/s00508-012-0223-0
Onofre Combarros	APOE dependent-association of PPAR-gamma genetic variants with Alzheimer's disease risk	2011	4	10.1016/j.neurobiolaging.2009.07.004
S M Raj	No association of multiple type 2 diabetes loci with type 1 diabetes	2009	3
Ema C. Brito	Previously Associated Type 2 Diabetes Variants May Interact With Physical Activity to Modify the Risk of Impaired Glucose Regulation and Type 2 Diabetes	2009	8	10.2337/db08-1623
Fatemeh Namvaran	Polymorphism of peroxisome proliferator-activated receptor γ (PPARγ) Pro12Ala in the Iranian population: Relation with insulin resistance and response to treatment with pioglitazone in type 2 diabetes.	2011	2	10.1016/j.ejphar.2011.09.158
Syed Fazal Jalil	Association of Pro12Ala (rs1801282) variant of PPAR gamma with Rheumatoid Arthritis in a Pakistani population.	2013	1	10.1007/s00296-013-2768-2
Stefan Wieczorek	Genetic variability of RXRB, PPARA, and PPARG in wegener's granulomatosis	2009	5	10.1155/2009/786781
George V Dedoussis	An age-dependent diet-modified effect of the PPARγ Pro12Ala polymorphism in children	2011	4	10.1016/j.metabol.2010.04.007
Wei Xu	PPARgamma polymorphisms and cancer risk: a meta-analysis involving 32,138 subjects.	2010	1	10.3892/or_00000895
Kyee-Zu Kim	Polymorphisms in adiposity-related genes are associated with age at menarche and menopause in breast cancer patients and healthy women.	2012	1	10.1093/humrep/des147
George V Dedoussis	Peroxisome proliferator-activated receptor-gamma (PPARgamma) Pro12Ala polymorphism and risk for pediatric obesity.	2009	2	10.1515/CCLM.2009.242
Luisa Klotz	Association of the PPAR?? gene polymorphism Pro12Ala with delayed onset of multiple sclerosis	2009	2	10.1016/j.neulet.2008.10.066
Viera Habalová	Rapid and cost effective genotyping method for polymorphisms in PPARG, PPARGC1 and TCF7L2 genes.	2009	0
Fatemeh Namvaran	Polymorphism of peroxisome proliferator-activated receptor γ (PPARγ) Pro12Ala in the Iranian population: Relation with insulin resistance and response to treatment with pioglitazone in type 2 diabetes	2011	4	10.1016/j.ejphar.2011.09.158
Hebe N Gouda	The association between the peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: a HuGE review and meta-analysis.	2010	25	10.1093/aje/kwp450
S M Raj	No association of multiple type 2 diabetes loci with type 1 diabetes	2009	11	10.1007/s00125-009-1391-y
Sun-Hee Oh	Association of peroxisome proliferator-activated receptor-gamma gene polymorphisms with the development of asthma.	2009	3	10.1016/j.rmed.2009.01.015
Valeriya Lyssenko	Clinical Risk Factors, DNA Variants, and the Development of Type 2 Diabetes.	2008	1	10.1056/NEJMoa0801869
Khadija Tariq	Association of Pro12Ala polymorphism in peroxisome proliferator activated receptor gamma with proliferative diabetic retinopathy.	2013	3
Kei Hang K Chan	Common Genetic Variants in Peroxisome Proliferator-Activated Receptor-γ (PPARG) and Type 2 Diabetes Risk Among Women's Health Initiative Postmenopausal Women.	2013	1
L Gallicchio	Genetic polymorphisms of peroxisome proliferator-activated receptors and the risk of cardiovascular morbidity and mortality in a community-based cohort in washington county, Maryland.	2008	3	10.1155/2008/276581
Chibo Liu	Quantitative evaluation of common polymorphism (rs1801282) in the PPARγ2 gene and hypertension susceptibility	2012	1	10.1016/j.gene.2012.04.035
Han-Yao Huang	Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population.	2007	11	10.1186/1471-2156-8-7
F J Torres-Espinola	Effects of maternal CG Pro12Ala PPAR PPAR(gamma)2 polymorphism on their infants neurodevelopmental scores at 18 months of age	2013	1	-
M Rossbauer	Influence of type 2 associated polymorphisms on weight development in offspring of mothers with gestational diabetes	2011	0
George V. Dedoussis	An age-dependent diet-modified effect of the PPAR?? Pro12Ala polymorphism in children	2011	9	10.1016/j.metabol.2010.04.007
Ema C Brito	Previously Associated Type 2 Diabetes Variants May Interact With Physical Activity to Modify the Risk of Impaired Glucose Regulation and Type 2 Diabetes	2009	2	10.2337/db08-1623
Samir Ben Ali	Gender-specific effect of Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma-2 gene on obesity risk and leptin levels in a Tunisian population.	2009	8	10.1016/j.clinbiochem.2009.08.019
Kei Hang K Chan	Common Genetic Variants in Peroxisome Proliferator-Activated Receptor-γ (PPARG) and Type 2 Diabetes Risk Among Women's Health Initiative Postmenopausal Women.	2013	1	-
Khalid Z Al-Shali	Genetic variation in PPARG encoding peroxisome proliferator-activated receptor gamma associated with carotid atherosclerosis.	2004	6	10.1161/01.STR.0000138784.68159.a5
Syed Tasleem Raza	Association of MTHFR and PPAR??2 gene polymorphisms in relation to type 2 diabetes mellitus cases among north Indian population	2012	2	10.1016/j.gene.2012.09.072
Jakub J Regieli	PPARγ Variant Influences Angiographic Outcome and 10-Year Cardiovascular Risk in Male Symptomatic Coronary Artery Disease Patients	2009	3	10.2337/dc08-1819
C. Markus	Variants of the human PPARG locus and the susceptibility to chronic periodontitis	2011	4	10.1177/1753425910392089
Onofre Combarros	APOE dependent-association of PPAR-?? genetic variants with Alzheimer's disease risk	2011	5	10.1016/j.neurobiolaging.2009.07.004
S M Raj	No association of multiple type 2 diabetes loci with type 1 diabetes.	2009	7	10.1007/s00125-009-1391-y
Tamer Bego	Association of PPARG and LPIN1 gene polymorphisms with metabolic syndrome and type 2 diabetes	2011	1
M Montagnana	The Pro12Ala polymorphism of the PPARG gene is not associated with the metabolic syndrome in an urban population of middle-aged Swedish individuals.	2008	4	-
Onofre Combarros	APOE dependent-association of PPAR-γ genetic variants with Alzheimer's disease risk.	2011	5	10.1016/j.neurobiolaging.2009.07.004
E C Brito	Previously associated type 2 diabetes variants may interact with physical activity to modify the risk of impaired glucose regulation and type 2 diabetes: a study of 16,003 Swedish adults.	2009	2	-
Dharambir Kaur Sanghera	PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in Asian Indian Sikhs: Pro12Ala still remains as the strongest predictor.	2010	12	10.1016/j.metabol.2009.07.043
Mariana L Tellechea	Pro12Ala polymorphism of the peroxisome proliferatoractivated receptor-gamma gene is associated with metabolic syndrome and surrogate measures of insulin resistance in healthy men: interaction with smoking status.	2009	4
Christopher Butt	PPAR-gamma gene polymorphisms and psoriatic arthritis.	2006	2
G V Dedoussis	An age-dependent diet-modified effect of the PPARgamma Pro12Ala polymorphism in children.	2010	1	-
Shintaro Omori	Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.	2008	20	-
Jeannet Lauenborg	Common Type 2 Diabetes Risk Gene Variants Associate with Gestational Diabetes	2009	1	10.1210/jc.2008-1336
Hebe N Gouda	The Association Between the Peroxisome Proliferator-Activated Receptor-gamma 2 (PPARG2) Pro12Ala Gene Variant and Type 2 Diabetes Mellitus: A HuGE Review and Meta-Analysis	2010	1	10.1093/aje/kwp450
Thomas Klockgether	Association of the PPARγ gene polymorphism Pro12Ala with delayed onset of multiple sclerosis	2009	2	10.1016/j.neulet.2008.10.066
Cosmo S D	The PPAR2 P12A polymorphism predicts incident microalbuminuria in patients with type 2 diabetes: Evidence from the bergamo nephrologic diabetes complications trial (benedict)	2009	0	-
Ming-Hsi Wang	Association of IL10 and other immune response- and obesity-related genes with prostate cancer in CLUE II.	2009	8	10.1002/pros.20933
Laura J Scott	A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.	2007	225	10.1126/science.1142382
Eva Fisher	A two-step association study identifies CAV2 rs2270188 single nucleotide polymorphism interaction with fat intake in type 2 diabetes risk.	2011	4	10.3945/jn.110.124206
George V Dedoussis	Peroxisome proliferator-activated receptor-gamma (PPARgamma) Pro12Ala polymorphism and risk for pediatric obesity.	2009	2	-
S Vol	Dietary fat intake and polymorphisms at the PPARG locus modulate BMI and type 2 diabetes risk in the D.E.S.I.R. prospective study	2012	8	10.1038/ijo.2011.91
Salvatore De Cosmo	Impact of the PPAR-γ2 Pro12Ala Polymorphism and ACE Inhibitor Therapy on New-Onset Microalbuminuria in Type 2 Diabetes: Evidence From BENEDICT	2009	7	10.2337/db09-0407
Matthias Folwaczny	Variants of the human PPARG locus and the susceptibility to chronic periodontitis	2011	0	10.1177/1753425910392089
E Rodriguez-Rodriguez	APOE dependent-association of PPAR-gamma genetic variants with Alzheimer's disease risk	2009	4	10.1016/j.neurobiolaging.2009.07.004
S De Cosmo	Inhibitor Therapy on New-Onset Microalbuminuria in Type 2 Diabetes : Evidence From BENEDICT	2009	2	10.2337/db09-0407.V.T.
Slavica Pecioska	Association between type 2 diabetes loci and measures of fatness.	2010	18	10.1371/journal.pone.0008541
Wendy Johnson	PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diabetes	2008	9	10.1016/j.neulet.2008.01.027
Janice S K Ho	Association of the PPARG Pro12Ala polymorphism with type 2 diabetes and incident coronary heart disease in a Hong Kong Chinese population	2012	1	10.1016/j.diabres.2012.03.012
M Ekelund	Genetic prediction of postpartum diabetes in women with gestational diabetes mellitus	2012	1	-
Y Wang	Nested case-control study of energy regulation candidate gene single nucleotide polymorphisms and breast cancer.	2007	1	-
Q Pei	PPAR-(gamma)2 and PTPRD gene polymorphisms influence type 2 diabetes patients' response to pioglitazone in China	2013	1	-
Lina Chen	Effect of the peroxisome proliferators-activated receptor (PPAR) gamma 3 gene on BMI in 1,210 school students from Morelos, Mexico.	2006	8
Matthias Folwaczny	Variants of the human PPARG locus and the susceptibility to chronic periodontitis.	2011	1	-

Evidence compiled by the Personal Genome Project

Gene	Impact	Trait	Summary	Inheritance
PPARG	Moderate clinical importance, Uncertain not reviewed	Diabetes Mellitus with Acanthosis Nigricans and Hypertension	-	undefined

Publications listed by Genome.gov

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Name	rs1801282
Chromosome	3
Position	12351626
Weight of evidence	232

SNP rs1801282

Basic Information

Genotype Frequency

Allele Frequency

Additional Information

Links to SNPedia

Publications on this SNP on the Public Library of Science:

Publications on this SNP on Mendeley

Evidence compiled by the Personal Genome Project

Publications listed by Genome.gov

Users who share this SNP:

Genome Browser

Contacts