openSNP | rs1801260

Links to SNPedia

Title	Summary
rs1801260 C/T	Normal (higher) risk of adhd symptoms.
rs1801260 T/T	Normal (higher) risk of adhd symptoms.
rs1801260 C/C	Lower adhd symptom scores.

Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).

Publications on this SNP on the Public Library of Science:

First Author	Title	Year of Publication	# of readers
Elena G. Ruano	REV-ERB ALPHA Polymorphism Is Associated with Obesity in the Spanish Obese Male Population	2014	1824
Leena Kovanen	ARNTL (BMAL1) and NPAS2 Gene Variants Contribute to Fertility and Seasonality	2010	4339
Karen L. Gamble	Shift Work in Nurses: Contribution of Phenotypes and Genotypes to Adaptation	2011	18271
Haipeng Ci	Clock Gene Modulates Roles of OXTR and AVPR1b Genes in Prosociality	2014	1955
Marta Garaulet	Ghrelin, Sleep Reduction and Evening Preference: Relationships to CLOCK 3111 T/C SNP and Weight Loss	2011	5945
Mitsue Yamaguchi	Circadian Rhythm Genes CLOCK and PER3 Polymorphisms and Morning Gastric Motility in Humans	2015	1537
Eva Talavera-Garcia	Influence of Obesity and Metabolic Disease on Carotid Atherosclerosis in Patients with Coronary Artery Disease (CordioPrev Study)	2016	451

Publications on this SNP on Mendeley

First Author	Title	Pub. Year	# of Readers	DOI
Donna L Robilliard	The 3111 Clock gene polymorphism is not associated with sleep and circadian rhythmicity in phenotypically characterized human subjects.	2002	24
Marta Garaulet	Ghrelin, sleep reduction and evening preference: relationships to CLOCK 3111 T/C SNP and weight loss.	2011	31	10.1371/journal.pone.0017435
F Benedetti	Clock genes beyond the clock: CLOCK genotype biases neural correlates of moral valence decision in depressed patients.	2008	23	-
M Garaulet	CLOCK gene is implicated in weight reduction in obese patients participating in a dietary programme based on the Mediterranean diet.	2010	24	-
C Kissling	A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder	2008	1
F Zhou	Functional polymorphisms of circadian positive feedback regulation genes and clinical outcome of Chinese patients with resected colorectal cancer.	2012	2	-
Taro Kishi	The CLOCK Gene and Mood Disorders: A Case-Control Study and Meta-analysis.	2011	3	10.3109/07420528.2011.609951
Raffaella Calati	T3111C clock single nucleotide polymorphism and mood disorders: a meta-analysis.	2010	8	-
Toshio Iwase	Mutation screening of the human Clock gene in circadian rhythm sleep disorders	2002	13	10.1016/S0165-1781(02)00006-9
F Benedetti	Clock genes beyond the clock: CLOCK genotype biases neural correlates of moral valence decision in depressed patients.	2008	26	10.1111/j.1601-183X.2007.00312.x
Kyu Young Lee	Association between CLOCK 3111T/C and preferred circadian phase in Korean patients with bipolar disorder.	2010	9	10.1016/j.pnpbp.2010.06.010
Edyta Reszka	Rotating night shift work and polymorphism of genes important for the regulation of circadian rhythm.	2012	5	10.5271/sjweh.3299
F Zhou	Functional polymorphisms of circadian positive feedback regulation genes and clinical outcome of Chinese patients with resected colorectal cancer	2012	2	10.1002/cncr.26348
Jing Zhang	The association of CLOCK gene T3111C polymorphism and hPER3 gene 54-nucleotide repeat polymorphism with Chinese Han people schizophrenics.	2011	8	10.1007/s11033-010-0114-2
Anne-Marie Chang	Human diurnal preference and circadian rhythmicity are not associated with the CLOCK 3111C/T gene polymorphism.	2011	5	10.1177/0748730411402026
C Bandín	Differences in circadian rhythmicity in CLOCK 3111T/C genetic variants in moderate obese women as assessed by thermometry, actimetry and body position.	2012	4	10.1038/ijo.2012.180
Xiaohui Xu	Association study between a polymorphism at the 3'-untranslated region of CLOCK gene and attention deficit hyperactivity disorder	2010	1	10.1186/1744-9081-6-48
Antonio Garcia-Rios	Beneficial effect of CLOCK gene polymorphism rs1801260 in combination with low-fat diet on insulin metabolism in the patients with metabolic syndrome.	2013	1	10.3109/07420528.2013.864300
Taro Kishi	The CLOCK Gene and Mood Disorders: A Case-Control Study and Meta-analysis.	2011	4	10.3109/07420528.2011.609951
Francesco Benedetti	Actimetric evidence that CLOCK 3111 T/C SNP influences sleep and activity patterns in patients affected by bipolar depression.	2007	22	10.1002/ajmg.b.30475
Toshio Iwase	Mutation screening of the human Clock gene in circadian rhythm sleep disorders.	2002	10
Xiaohui Xu	Association study between a polymorphism at the 3'-untranslated region of CLOCK gene and attention deficit hyperactivity disorder	2010	11	10.1186/1744-9081-6-48
Jie Zhang	Association of CLOCK gene variants with semen quality in idiopathic infertile Han-Chinese males	2012	1	10.1016/j.rbmo.2012.07.018
Marta Garaulet	Genetic variants in human CLOCK associate with total energy intake and cytokine sleep factors in overweight subjects (GOLDN population).	2010	18	10.1038/ejhg.2009.176
Taro Kishi	The CLOCK gene and mood disorders: a case-control study and meta-analysis.	2011	5	10.3109/07420528.2011.609951
C Bandín	Differences in circadian rhythmicity in CLOCK 3111T/C genetic variants in moderate obese women as assessed by thermometry, actimetry and body position.	2013	7	10.1038/ijo.2012.180
Christian Kissling	A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder.	2008	8	10.1002/ajmg.b.30602
M Garaulet	CLOCK gene is implicated in weight reduction in obese patients participating in a dietary programme based on the Mediterranean diet.	2010	26	10.1038/ijo.2009.255
Xiaohui Xu	Association study between a polymorphism at the 3'-untranslated region of CLOCK gene and attention deficit hyperactivity disorder.	2010	12	10.1186/1744-9081-6-48
Francesco Benedetti	Actimetric evidence that CLOCK 3111 T/C SNP influences sleep and activity patterns in patients affected by bipolar depression.	2007	18	-
A Terracciano	Genome-wide association scan for five major dimensions of personality.	2010	59	10.1038/mp.2008.113
Feng Zhou	Functional polymorphisms of circadian positive feedback regulation genes and clinical outcome of Chinese patients with resected colorectal cancer.	2012	11	10.1002/cncr.26348
Marta Garaulet	Ghrelin, sleep reduction and evening preference: Relationships to clock 3111 T/C SNP and weight loss	2011	38	10.1371/journal.pone.0017435
Cecilia Galbete	Physical activity and sex modulate obesity risk linked to 3111T/C gene variant of the CLOCK gene in an elderly population: the SUN Project.	2012	3	10.3109/07420528.2012.728657
Ayelet Ziv-Gal	Genetic polymorphisms in the aryl hydrocarbon receptor-signaling pathway and sleep disturbances in middle-aged women	2013	2	10.1016/j.sleep.2013.04.007
C Kissling	A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder	2008	5	10.1002/ajmg.b.30602
M Garaulet	SIRT1 and CLOCK 3111T>C combined genotype is associated with evening preference and weight loss resistance in a behavioral therapy treatment for obesity.	2012	5	10.1038/ijo.2011.270
T Kishi	The CLOCK gene and mood disorders: a case-control study and meta-analysis	2011	1	10.3109/07420528.2011.611602\r10.3109/07420528.2011.609951
E M Scott	Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man.	2008	18	-
B Paul	Circadian rhythm of homocysteine is hCLOCK genotype dependent	2014	2	10.1007/s11033-014-3223-5
Theodoros Karantanos	Association of the clock genes polymorphisms with colorectal cancer susceptibility.	2013	1	10.1002/jso.23434
Mario Pedrazzoli	Interactions of polymorphisms in different clock genes associated with circadian phenotypes in humans.	2010	13	10.1590/S1415-47572010005000092
Kyu Young Lee	Association between CLOCK 3111T/C and preferred circadian phase in Korean patients with bipolar disorder.	2010	7	-
X Xu	Association study between a polymorphism at the 3'-untranslated region of CLOCK gene and attention deficit hyperactivity disorder	2010	1	1744-9081-6-48 [pii]\r10.1186/1744-9081-6-48
Kyu Young Lee	Association between CLOCK 3111T/C and preferred circadian phase in Korean patients with bipolar disorder	2010	11	10.1016/j.pnpbp.2010.06.010
Raffaella Calati	T3111C clock single nucleotide polymorphism and mood disorders: a meta-analysis.	2010	10	10.3109/07420521003681480
Christian Kissling	A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder.	2008	16	-
C Kissling	A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder	2007	1	10.1002/ajmg.b.30602 [doi]
C Kissling	A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder	2007	2
Jing Zhang	The association of CLOCK gene T3111C polymorphism and hPER3 gene 54-nucleotide repeat polymorphism with Chinese Han people schizophrenics.	2011	8	-
Feng Zhou	Functional polymorphisms of circadian positive feedback regulation genes and clinical outcome of Chinese patients with resected colorectal cancer.	2012	12	10.1002/cncr.26348
Cecilia Galbete	Physical activity and sex modulate obesity risk linked to 3111T/C gene variant of the CLOCK gene in an elderly population: the SUN Project.	2012	3	10.3109/07420528.2012.728657

Evidence compiled by the Personal Genome Project

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Publications listed by Genome.gov

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Name	rs1801260
Chromosome	4
Position	55435202
Weight of evidence	81

SNP rs1801260

Basic Information

Genotype Frequency

Allele Frequency

Additional Information

Links to SNPedia

Publications on this SNP on the Public Library of Science:

Publications on this SNP on Mendeley

Evidence compiled by the Personal Genome Project

Publications listed by Genome.gov

Users who share this SNP:

Genome Browser

Contacts