openSNP | rs1800872

Links to SNPedia

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Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).

Publications on this SNP on the Public Library of Science:

First Author	Title	Year of Publication	# of readers
Marleen M. Welsh	Genetic Determinants of UV-Susceptibility in Non-Melanoma Skin Cancer	2011	4640
Yan Zhang	Lymphotoxin Alpha (LTA) Polymorphism Is Associated with Prognosis of Non-Hodgkin’s Lymphoma in a Chinese Population	2013	1991
Sadeep Shrestha	Interleukin-10 (IL-10) Pathway: Genetic Variants and Outcomes of HIV-1 Infection in African American Adolescents	2010	4196
Esther Erdei	Cytokines and Tumor Metastasis Gene Variants in Oral Cancer and Precancer in Puerto Rico	2013	2522
Hongqiang Sun	The Interaction of Polymorphisms of IL10 and DBH Was Associated with General Symptoms of PANSS with TD in Chinese Han Schizophrenic Patients	2013	1425
Myung-Han Hyun	Interleukin-10 Promoter Gene Polymorphisms and Susceptibility to Asthma: A Meta-Analysis	2013	3827
Cristina Cunha	Human Genetic Susceptibility to Invasive Aspergillosis	2013	4832
Lei Gao	Association of Interleukin-10 Polymorphisms with Schizophrenia: A Meta-Analysis	2014	1913
Qi Ding	The Interleukin-10 Promoter Polymorphism rs1800872 (-592C>A), Contributes to Cancer Susceptibility: Meta-Analysis of 16 785 Cases and 19 713 Controls	2013	2574
Margrit Urbanek	The Role of Inflammatory Pathway Genetic Variation on Maternal Metabolic Phenotypes during Pregnancy	2012	4645
Paul J. McLaren	Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls	2013	7204
Susanna Esposito	Genetic Polymorphisms and Sepsis in Premature Neonates	2014	5500
Carolina Minnicelli	Relationship of Epstein-Barr Virus and Interleukin 10 Promoter Polymorphisms with the Risk and Clinical Outcome of Childhood Burkitt Lymphoma	2012	2563
Daisuke Sakurai	Preferential Binding to Elk-1 by SLE-Associated IL10 Risk Allele Upregulates IL10 Expression	2013	5074
Jing-Jing Peng	Single Nucleotide Polymorphisms of PIN1 Promoter Region and Cancer Risk: Evidence from a Meta-Analysis	2013	1741
Gaoqiang Xie	Relationship of Serum Interleukin-10 and Its Genetic Variations with Ischemic Stroke in a Chinese General Population	2013	1975
Mark G. J. de Boer	Influence of Polymorphisms in Innate Immunity Genes on Susceptibility to Invasive Aspergillosis after Stem Cell Transplantation	2011	4083
Ebun Omoyinmi	Association of the IL-10 Gene Family Locus on Chromosome 1 with Juvenile Idiopathic Arthritis (JIA)	2012	3318
Maris Kuningas	Selection for Genetic Variation Inducing Pro-Inflammatory Responses under Adverse Environmental Conditions in a Ghanaian Population	2009	3238
Vibeke Andersen	Interactions between Diet, Lifestyle and IL10, IL1B, and PTGS2/COX-2 Gene Polymorphisms in Relation to Risk of Colorectal Cancer in a Prospective Danish Case-Cohort Study	2013	2805
Cinzia Ciccacci	A Multilocus Genetic Study in a Cohort of Italian SLE Patients Confirms the Association with STAT4 Gene and Describes a New Association with HCP5 Gene	2014	2294
Sara Corchado	Influence of Genetic Polymorphisms of Tumor Necrosis Factor Alpha and Interleukin 10 Genes on the Risk of Liver Cirrhosis in HIV-HCV Coinfected Patients	2013	1848
Yan Zhang	Tumor Necrosis Factor-α Induced Protein 8 Polymorphism and Risk of Non-Hodgkin’s Lymphoma in a Chinese Population: A Case-Control Study	2012	2906
Chuan-Jiang Li	Impact of the CYP3A5, CYP3A4, COMT, IL-10 and POR Genetic Polymorphisms on Tacrolimus Metabolism in Chinese Renal Transplant Recipients	2014	3792
Sara Corchado	Liver Fibrosis, Host Genetic and Hepatitis C Virus Related Parameters as Predictive Factors of Response to Therapy against Hepatitis C Virus in HIV/HCV Coinfected Patients	2014	1723
Jun Jin	Relationship between Interleukin-10 −1082A/G Polymorphism and Risk of Ischemic Stroke: A Meta-Analysis	2014	1420
Michelle A. T. Hildebrandt	Genetic Variants in Inflammation-Related Genes Are Associated with Radiation-Induced Toxicity Following Treatment for Non-Small Cell Lung Cancer	2010	6708
Marcela Caleffi da Costa Lima Caniatti	Association of Cytokines in Individuals Sensitive and Insensitive to Dust Mites in a Brazilian Population	2014	1961
Francesc Vidal	Pharmacogenetics of Efficacy and Safety of HCV Treatment in HCV-HIV Coinfected Patients: Significant Associations with IL28B and SOCS3 Gene Variants	2012	4283
Jacques Fellay	Common Genetic Variation and the Control of HIV-1 in Humans	2009	20820
Thorsten Thye	IL10 Haplotype Associated with Tuberculin Skin Test Response but Not with Pulmonary TB	2009	3394
Steffen Bank	Polymorphisms in the Inflammatory Pathway Genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG Are Associated with Susceptibility of Inflammatory Bowel Disease in a Danish Cohort	2014	5137
Xiaoyan Liu	Association Study of Candidate Gene Polymorphisms with Amnestic Mild Cognitive Impairment in a Chinese Population	2012	2464
Eero Lauhkonen	IL-10 Gene Polymorphisms Are Associated with Post-Bronchiolitis Lung Function Abnormalities at Six Years of Age	2015	911
Yong An	IL-10 Genetic Polymorphisms Were Associated with Valvular Calcification in Han, Uygur and Kazak Populations in Xinjiang, China	2015	555
Lucia Elena Alvarado-Arnez	Association of IL10 Polymorphisms and Leprosy: A Meta-Analysis	2015	1459
Kaspar René Nielsen	Inherited Inflammatory Response Genes Are Associated with B-Cell Non-Hodgkin’s Lymphoma Risk and Survival	2015	1434
Heiko Schotte	Putative IL-10 Low Producer Genotypes Are Associated with a Favourable Etanercept Response in Patients with Rheumatoid Arthritis	2015	590
Jiachuan Xiong	Lack of Association between Interleukin-10 Gene Polymorphisms and Graft Rejection Risk in Kidney Transplantation Recipients: A Meta-Analysis	2015	873
Jung-Pil Jang	Multiplex Genotyping of Cytokine Gene SNPs Using Fluorescence Bead Array	2015	2246
Shirley B. Russell	Pleiotropic Effects of Immune Responses Explain Variation in the Prevalence of Fibroproliferative Diseases	2015	4266
Wanda G. H. Han	Association of Vitamin D Receptor Polymorphism with Susceptibility to Symptomatic Pertussis	2016	2459
Mariana Milano	Single Nucleotide Polymorphisms in IL17A and IL6 Are Associated with Decreased Risk for Pulmonary Tuberculosis in Southern Brazilian Population	2016	506

Publications on this SNP on Mendeley

First Author	Title	Pub. Year	# of Readers	DOI
Jin-Guang Yao	Genetic variation in interleukin-10 gene and risk of oral cancer.	2008	4	10.1016/j.cca.2007.10.012
Shweta Aggarwal	Genetic Variations and Interactions in Anti-inflammatory Cytokine Pathway Genes in the Outcome of Leprosy: A Study Conducted on a MassARRAY Platform.	2011	6	10.1093/infdis/jir516
Alice H. Wang	The effect of IL-10 genetic variation and interleukin 10 serum levels on Crohn's disease susceptibility in a New Zealand population	2011	7	10.1016/j.humimm.2011.02.014
Madhukar Saxena	An Interleukin-10 Gene Promoter Polymorphism (−592A/C) Associated with Type 2 Diabetes: A North Indian Study	2012	1	10.1007/s10528-012-9499-z
Yeon Hee Park	Interaction between BCL2 and interleukin-10 gene polymorphisms alter outcomes of diffuse large B-cell lymphoma following rituximab plus CHOP chemotherapy.	2009	6	10.1158/1078-0432.CCR-08-1588
Madhukar Saxena	An interleukin-10 gene promoter polymorphism (-592A/C) associated with type 2 diabetes: a North Indian study.	2012	1	10.1007/s10528-012-9499-z
Kirvis Torres-Poveda	The SNP at -592 of human IL-10 gene is associated with serum IL-10 levels and increased risk for human papillomavirus cervical lesion development.	2012	12	10.1186/1750-9378-7-32
Lei Jin	Interleukin-10 promoter variants predict HPV-positive tumors and survival of squamous cell carcinoma of the oropharynx.	2013	2	10.1096/fj.12-226803
Chee Seng Hee	Comparison of single nucleotide polymorphisms in the human interleukin-10 gene promoter between rheumatoid arthritis patients and normal subjects in Malaysia.	2007	3	-
Y M Zhang	Meta-analysis of epidemiological studies of association of two polymorphisms in the interleukin-10 gene promoter and colorectal cancer risk	2012	1	10.4238/2012.September.25.7
Ke-Da Yu Ao-Xiang Chen	The associations between two polymorphisms in the interleukin-10 gene promoter and breast cancer risk	2010	5	10.1007/s10549-010-1133-3
Tuo Kang Chen	Association between human IL-10 gene polymorphisms and serum IL-10 level in patients with food allergy	2012	2	10.1016/j.jfma.2011.11.027
M. Salakhutdinova	174 The prognostic value of angiogenesis genes polymorphisms in women with infiltrating ductal breast carcinoma	2010	1	10.1016/S1359-6349(10)70205-6
Mao Sun	Inflammatory factors gene polymorphism in recurrent oral ulceration.	2013	4	10.1111/jop.12048
D S Cross	Genetic factors associated with non-fatal myocardial infarction and hospitalized unstable angina - A marshfield clinic case-cohort study	2010	1	-
Nils Schoof	Interleukin-10 gene polymorphisms are associated with freedom from treatment failure for patients with Hodgkin lymphoma.	2013	3	10.1634/theoncologist.2012-0291
Giusi Irma Forte	Relevance of Gamma Interferon, Tumor Necrosis Factor Alpha, and Interleukin-10 Gene Polymorphisms to Susceptibility to Mediterranean Spotted Fever	2009	3	10.1128/CVI.00121-09
Nathalie Gaudreault	Replication of genetic association studies in aortic stenosis in adults	2011	10	10.1016/j.amjcard.2011.06.050
L A Davis	Association of medicaons and rheumatoid arthritis susceptibility polymorphism with lipid profiles in patients with rheumatoid arthritis	2011	1	-
Lei Jin	Interleukin-10 promoter variants predict HPV-positive tumors and survival of squamous cell carcinoma of the oropharynx.	2013	1	10.1096/fj.12-226803
C S Hee	Comparison of single nucleotide polymorphisms in the human interleukin-10 gene promoter between rheumatoid arthritis patients and normal subjects in Malaysia	2007	1	-
Nan Liu	An association of interleukin-10 gene polymorphisms with Graves' disease in two Chinese populations.	2011	2	-
Qi Ding	The interleukin-10 promoter polymorphism rs1800872 (-592C>A), contributes to cancer susceptibility: meta-analysis of 16,785 cases and 19,713 controls.	2013	1	10.1371/journal.pone.0057246
A Schuurhof	Local interleukin-10 production during respiratory syncytial virus bronchiolitis is associated with post-bronchiolitis wheeze	2011	3	-
Claire Pouplard	Interleukin-10 promoter microsatellite polymorphisms influence the immune response to heparin and the risk of heparin-induced thrombocytopenia	2012	3	10.1016/j.thromres.2011.09.033
Jin-Guang Yao	Genetic variation in interleukin-10 gene and risk of oral cancer.	2008	4	-
Hongqiang Sun	The Interaction of Polymorphisms of IL10 and DBH Was Associated with General Symptoms of PANSS with TD in Chinese Han Schizophrenic Patients	2013	3	10.1371/journal.pone.0070963
Najwa Mhmoud	Association of IL-10 and CCL5 single nucleotide polymorphisms with tuberculosis in the Sudanese population.	2013	1	10.1111/tmi.12141
Kui Zhang	The IL-10 promoter haplotype and cancer risk: evidence from a meta-analysis	2012	1	10.1007/s10689-012-9533-7
Jia-Ming Sun	Interleukin 10 rs1800872 T>G polymorphism was associated with an increased risk of esophageal cancer in a Chinese population.	2013	1	-
Yeon Hee Park	Interaction between BCL2 and interleukin-10 gene polymorphisms alter outcomes of diffuse large B-cell lymphoma following rituximab plus CHOP chemotherapy.	2009	4	-
Robert Y L Zee	An evaluation of candidate genes of inflammation and thrombosis in relation to the risk of venous thromboembolism: The Women's Genome Health Study.	2009	2	-
F. A. Castro	TLR-3 polymorphism is an independent prognostic marker for stage II colorectal cancer	2011	13	10.1016/j.ejca.2010.12.011
Lei Jin	Interleukin-10 promoter variants predict HPV-positive tumors and survival of squamous cell carcinoma of the oropharynx.	2013	4	10.1096/fj.12-226803
Yan-Feng Zou	Lack of association of IL-10 gene polymorphisms with prostate cancer: Evidence from 11,581 subjects.	2011	4	10.1016/j.ejca.2010.11.034
Miikael Heiskanen	Polymorphism in the IL10 promoter region and early markers of atherosclerosis: The Cardiovascular Risk in Young Finns Study	2010	1	10.1016/j.atherosclerosis.2009.06.032
Eva Cochery-Nouvellon	Interleukin 10 gene promoter polymorphisms in women with pregnancy loss: preferential association with embryonic wastage.	2009	2	10.1095/biolreprod.108.072215
Blanca Rueda	Influence of interleukin 10 promoter polymorphisms in susceptibility to giant cell arteritis in Northwestern Spain.	2007	0	-
Miguel Cruz	The TGF-B1 and IL-10 gene polymorphisms are associated with risk of developing silent myocardial ischemia in the diabetic patients	2013	3	10.1016/j.imlet.2013.09.007
Qi Ding	The interleukin-10 promoter polymorphism rs1800872 (-592C>A), contributes to cancer susceptibility: meta-analysis of 16,785 cases and 19,713 controls.	2013	5	10.1371/journal.pone.0057246
Luca Scapoli	IL6 and IL10 are genetic susceptibility factors of periodontal disease.	2012	0	10.4103/1735-3327.109754
D Kube	Effect of interleukin-10 gene polymorphisms on clinical outcome of patients with aggressive non-Hodgkin's lymphoma: an exploratory study	2008	1	-
Walid Ben-Selma	Association of TNF-?? and IL-10 polymorphisms with tuberculosis in Tunisian populations	2011	13	10.1016/j.micinf.2011.04.009
Gaoqiang Xie	Relationship of serum interleukin-10 and its genetic variations with ischemic stroke in a Chinese general population.	2013	2	10.1371/journal.pone.0074126
Juliana Garcia de Oliveira	Profiles of gene polymorphisms in cytokines and Toll-like receptors with higher risk for gastric cancer.	2013	2	10.1007/s10620-012-2460-5
Vibeke Andersen	Interaction between interleukin-10 (IL-10) polymorphisms and dietary fibre in relation to risk of colorectal cancer in a Danish case-cohort study	2012	9	10.1186/1471-2407-12-183
Najwa Mhmoud	Association of IL-10 and CCL5 single nucleotide polymorphisms with tuberculosis in the Sudanese population.	2013	2	10.1111/tmi.12141
Adjimon Gatien Lokossou	Association of IL-4 and IL-10 maternal haplotypes with immune responses to P. falciparum in mothers and newborns.	2013	3	10.1186/1471-2334-13-215
Jan LL Kimpen	Local interleukin-10 production during respiratory syncytial virus bronchiolitis is associated with post-bronchiolitis wheeze	2011	7	10.1186/1465-9921-12-121
Jin Guang Yao	Genetic variation in interleukin-10 gene and risk of oral cancer	2008	5	10.1016/j.cca.2007.10.012
Madhukar Saxena	An Interleukin-10 Gene Promoter Polymorphism (-592A/C) Associated with Type 2 Diabetes: A North Indian Study.	2012	4	10.1007/s10528-012-9499-z
Yan-Feng Zou	Lack of association of IL-10 gene polymorphisms with prostate cancer: evidence from 11,581 subjects.	2011	14	-
Qi Ding	The Interleukin-10 Promoter Polymorphism rs1800872 (-592C>A), Contributes to Cancer Susceptibility: Meta-Analysis of 16 785 Cases and 19 713 Controls	2013	6	10.1371/journal.pone.0057246
Hongqiang Sun	The Interaction of Polymorphisms of IL10 and DBH Was Associated with General Symptoms of PANSS with TD in Chinese Han Schizophrenic Patients	2013	3	10.1371/journal.pone.0070963
Eva Cochery-Nouvellon	Interleukin 10 gene promoter polymorphisms in women with pregnancy loss: preferential association with embryonic wastage.	2009	1	-
H Dean Hosgood	IL10 and TNF variants and risk of non-Hodgkin lymphoma among three Asian populations.	2013	1	10.1007/s12185-013-1345-5
Nora Cardona-Castro	IL-10 gene promoter polymorphisms and leprosy in a Colombian population sample	2011	2	10.7705/biomedica.v32i1.386
G I Forte	Risk profiles in type 2 diabetes (metabolic syndrome): integration of IL-10 polymorphisms and laboratory parameters to identify vascular damages related complications.	2010	3	-
Yan Feng Zou	Lack of association of IL-10 gene polymorphisms with prostate cancer: Evidence from 11,581 subjects	2011	19	10.1016/j.ejca.2010.11.034
Nathalie Gaudreault	Replication of Genetic Association Studies in Aortic Stenosis in Adults	2011	7	10.1016/j.amjcard.2011.06.050
G I Forte	Relevance of Interferon-gamma, Tumor Necrosis Factor-alpha and Interleukin 10 gene polymorphisms for Mediterranean Spotted Fever susceptibility	2009	1	-
Madhukar Saxena	An Interleukin-10 Gene Promoter Polymorphism (-592A/C) Associated with Type 2 Diabetes: A North Indian Study.	2012	1	10.1007/s10528-012-9499-z
Paul J Dluzniewski	Variation in IL10 and Other Genes Involved in the Immune Response and in Oxidation and Prostate Cancer Recurrence.	2012	2	10.1158/1055-9965.EPI-12-0458
Olfat G Shaker	Single-nucleotide polymorphisms of IL-10 and IL-28B as predictors of the response of IFN therapy in HCV genotype 4-infected children.	2013	2	10.1097/MPG.0b013e31828febf0
Liwei Zou	The association between three promoter polymorphisms of IL-10 and inflammatory bowel diseases (IBD): A meta-analysis.	2014	4	10.3109/08916934.2013.843672
N Schoof	Distal and proximal interleukin (IL)-10 promoter polymorphisms associated with risk of cutaneous melanoma development: a case--control study.	2009	0	-
Walid Ben-Selma	Association of TNF-α and IL-10 polymorphisms with tuberculosis in Tunisian populations.	2011	6	-
Qi Ding	The interleukin-10 promoter polymorphism rs1800872 (-592C>A), contributes to cancer susceptibility: meta-analysis of 16,785 cases and 19,713 controls.	2013	6	10.1371/journal.pone.0057246
Neogelia Pereira Almeida	Polymorphisms of the cytokine genes TGFB1 and IL10 in a mixed-race population with Crohn's disease.	2013	4	10.1186/1756-0500-6-387
T Saitoh	The cytokine polymorphisms affect the severity of thrombocytopenia at diagnosis in chronic immune thrombocytopenia	2012	2	-
Adjimon Gatien Lokossou	Association of IL-4 and IL-10 maternal haplotypes with immune responses to P. falciparum in mothers and newborns.	2013	1	10.1186/1471-2334-13-215

Evidence compiled by the Personal Genome Project

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Publications listed by Genome.gov

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Name	rs1800872
Chromosome	1
Position	206773062
Weight of evidence	157

SNP rs1800872

Basic Information

Genotype Frequency

Allele Frequency

Additional Information

Links to SNPedia

Publications on this SNP on the Public Library of Science:

Publications on this SNP on Mendeley

Evidence compiled by the Personal Genome Project

Publications listed by Genome.gov

Users who share this SNP:

Genome Browser

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