openSNP | rs1800588

Links to SNPedia

Title	Summary
rs1800588 C/C	Common in complete genomics

Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).

Publications on this SNP on the Public Library of Science:

First Author	Title	Year of Publication	# of readers
Céline Verdier	Association of Hepatic Lipase -514T Allele with Coronary Artery Disease and Ankle-Brachial Index, Dependence on the Lipoprotein Phenotype: The GENES Study	2013	1171
Molly A. Hall	Detection of Pleiotropy through a Phenome-Wide Association Study (PheWAS) of Epidemiologic Data as Part of the Environmental Architecture for Genes Linked to Environment (EAGLE) Study	2014	4663
Ming-Huei Chen	Using Family-Based Imputation in Genome-Wide Association Studies with Large Complex Pedigrees: The Framingham Heart Study	2012	3340
Sebastian Okser	Genetic Variants and Their Interactions in the Prediction of Increased Pre-Clinical Carotid Atherosclerosis: The Cardiovascular Risk in Young Finns Study	2010	8490
Wenjing Ou	Association of CVD Candidate Gene Polymorphisms with Ischemic Stroke and Cerebral Hemorrhage in Chinese Individuals	2014	2033
Guillaume Lettre	Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project	2011	20105
Laura López-Ríos	Interaction between Cholesteryl Ester Transfer Protein and Hepatic Lipase Encoding Genes and the Risk of Type 2 Diabetes: Results from the Telde Study	2011	2335
Bénédicte M. J. Merle	Association of HDL-Related Loci with Age-Related Macular Degeneration and Plasma Lutein and Zeaxanthin: the Alienor Study	2013	3707
Rahul C. Deo	Genetic Differences between the Determinants of Lipid Profile Phenotypes in African and European Americans: The Jackson Heart Study	2009	8916
Marquitta J. White	SHBG Gene Polymorphism (rs1799941) Associates with Metabolic Syndrome in Children and Adolescents	2015	1437
Fotios Drenos	Networks in Coronary Heart Disease Genetics As a Step towards Systems Epidemiology	2015	1763

Publications on this SNP on Mendeley

First Author	Title	Pub. Year	# of Readers	DOI
M Crous-Bou	Genetic polymorphisms in fatty acid metabolism genes and colorectal cancer.	2012	6	10.1093/mutage/ger066
D. A. Phares	Hepatic lipase gene -514C>T variant is associated with exercise training-induced changes in VLDL and HDL by lipoprotein lipase	2011	2	10.1152/japplphysiol.00567.2011
M Crous-Bou	Genetic polymorphisms in fatty acid metabolism genes and colorectal cancer.	2012	3	10.1093/mutage/ger066
R Yang	A genome-wide linkage scan identifies multiple QTLs for HDL cholesterol levels in families with premature CAD and MI	2010	0	-
B A C van Acker	High HDL cholesterol does not protect against coronary artery disease when associated with combined cholesteryl ester transfer protein and hepatic lipase gene variants	2008	1	10.1016/j.atherosclerosis.2007.11.019
Ugur Hodoglugil	Polymorphisms in the hepatic lipase gene affect plasma HDL-cholesterol levels in a Turkish population[S]	2010	6	10.1194/jlr.P001578
Iwona Rudkowska	Gene-diet interactions on plasma lipid levels in the Inuit population	2013	1	10.1017/S0007114512002231
Bernadette A C van Acker	High HDL cholesterol does not protect against coronary artery disease when associated with combined cholesteryl ester transfer protein and hepatic lipase gene variants.	2008	7	10.1016/j.atherosclerosis.2007.11.019
Y Lu	Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.	2008	1
Elise F Villard	Genetic determination of plasma cholesterol efflux capacity is gender-specific and independent of HDL-cholesterol levels.	2013	5	10.1161/ATVBAHA.112.300979
Iwona Rudkowska	Gene-diet interactions on plasma lipid levels in the Inuit population.	2013	3	10.1017/S0007114512002231
Elise F Villard	Genetic Determination of Plasma Cholesterol Efflux Capacity Is Gender-Specific and Independent of HDL-Cholesterol Levels.	2013	3	10.1161/ATVBAHA.112.300979
Bernadette A C Van Acker	High HDL cholesterol does not protect against coronary artery disease when associated with combined cholesteryl ester transfer protein and hepatic lipase gene variants.	2008	6	-
Y-M Fan	Hepatic lipase promoter C-480T polymorphism is associated with serum lipids levels, but not subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study.	2009	3	-
Y-M Fan	Hepatic lipase promoter C-480T polymorphism is associated with serum lipids levels, but not subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study.	2009	4	10.1111/j.1399-0004.2009.01180.x
Céline Verdier	Association of hepatic lipase -514T allele with coronary artery disease and ankle-brachial index, dependence on the lipoprotein phenotype: the GENES study.	2013	2	10.1371/journal.pone.0067805
Yun Liu	Effects of genetic variants on lipid parameters and dyslipidemia in a Chinese population.	2011	6	10.1194/jlr.P007476
Ugur Hodoglugil	Polymorphisms in the hepatic lipase gene affect plasma HDL-cholesterol levels in a Turkish population.	2010	6	10.1194/jlr.P001578
Rong Yang	A genome-wide linkage scan identifies multiple quantitative trait loci for HDL-cholesterol levels in families with premature CAD and MI.	2010	2	10.1194/jlr.M004325
Rong Yang	A genome-wide linkage scan identifies multiple quantitative trait loci for HDL-cholesterol levels in families with premature CAD and MI	2010	1	10.1194/jlr.M004325

Evidence compiled by the Personal Genome Project

There are no results from the Personal Genome Project yet. Please come back later.

Publications listed by Genome.gov

First Author	Title	Journal	Publication Date	Trait	p-value	Confidence Interval
Kathiresan S	Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.	Nat Genet	01/13/2008	HDL cholesterol	2.0e-32	[0.12-0.16] % SD higher

Name	rs1800588
Chromosome	15
Position	58431476
Weight of evidence	49

SNP rs1800588

Basic Information

Genotype Frequency

Allele Frequency

Additional Information

Links to SNPedia

Publications on this SNP on the Public Library of Science:

Publications on this SNP on Mendeley

Evidence compiled by the Personal Genome Project

Publications listed by Genome.gov

Users who share this SNP:

Genome Browser

Contacts