Links to SNPedia
||Normal; no change in warfarin metabolism
||Cyp2c9*2 homozygote; average 40% reduction in warfarin metabolism
||No summary provided.
||Cyp2c9*2 carrier; average 20% reduction in warfarin metabolism
Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).
Publications on this SNP on the Public Library of Science:
Publications on this SNP on Mendeley
Evidence compiled by the Personal Genome Project
||Moderate clinical importance, pharmacogenetic
||This variant, also called CYP2C9*2, is a pharmacogenetic variant that modulates sensitivity for Warfarin (due to reduced metabolism). This variant is associated with Caucasians. The FDA has approved reduced recommended Warfarin dosage based on the presence of this variant.
Publications listed by Genome.gov
Users who share this SNP: