openSNP
Toggle
News
Data
SNPs
Genotypes
Phenotypes
Phenotypes Pictures
Open Humans Connections
Latest Data
About
About Us
Statistics
FAQ
Sign In
x
It seems like you have JavaScript disabled. This will make some features of openSNP.org, like the drop-down menus, break.
SNP rs174537
Basic Information
Name
rs174537
Chromosome
11
Position
61785208
Weight of evidence
57
Genotype Frequency
Allele Frequency
Additional Information
SNPedia (3)
PLoS (9)
Mendeley (24)
Personal Genome Project (0)
Genome.gov (0)
Other users (1555)
Comments (0)
Links to SNPedia
Title
Summary
rs174537 T/T
Lower ldl-c and total cholesterol
rs174537 G/T
Common; higher ldl-c and total cholesterol
rs174537 G/G
Common; higher ldl-c and total cholesterol
Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).
Publications on this SNP on the Public Library of Science:
First Author
Title
Year of Publication
# of readers
Si-Wei Li
FADS Gene Polymorphisms Confer the Risk of Coronary Artery Disease in a Chinese Han Population through the Altered Desaturase Activities: Based on High-Resolution Melting Analysis
2013
3284
Andrew A. Hicks
Genetic Determinants of Circulating Sphingolipid Concentrations in European Populations
2009
10685
Toshiko Tanaka
Genome-Wide Association Study of Plasma Polyunsaturated Fatty Acids in the InCHIANTI Study
2009
12599
Zhou Zhang
Association of Genetic Loci with Blood Lipids in the Chinese Population
2011
3242
Rasika A. Mathias
Adaptive Evolution of the
FADS
Gene Cluster within Africa
2012
10775
Timothy D. Howard
DNA Methylation in an Enhancer Region of the FADS Cluster Is Associated with FADS Activity in Human Liver
2014
2187
Maria Azrad
Prostatic Alpha-Linolenic Acid (ALA) Is Positively Associated with Aggressive Prostate Cancer: A Relationship Which May Depend on Genetic Variation in ALA Metabolism
2012
8227
William R. Wikoff
Pharmacometabolomics Reveals Racial Differences in Response to Atenolol Treatment
2013
6099
Eva Morales
Genetic Variants of the
FADS
Gene Cluster and
ELOVL
Gene Family, Colostrums LC-PUFA Levels, Breastfeeding, and Child Cognition
2011
8040
Publications on this SNP on Mendeley
First Author
Title
Pub. Year
# of Readers
DOI
Si-Wei Li
FADS gene polymorphisms confer the risk of coronary artery disease in a Chinese Han population through the altered desaturase activities: based on high-resolution melting analysis.
2013
2
10.1371/journal.pone.0055869
Si Wei Li
FADS Gene Polymorphisms Confer the Risk of Coronary Artery Disease in a Chinese Han Population through the Altered Desaturase Activities: Based on High-Resolution Melting Analysis
2013
3
10.1371/journal.pone.0055869
Toshiko Tanaka
Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study.
2009
25
10.1371/journal.pgen.1000338
L G Gillingham
Dietary oils and FADS1-FADS2 genetic variants modulate [13C]alpha-linolenic acid metabolism and plasma fatty acid composition
2013
2
10.3945/ajcn.112.043117
Seul Hee Hong
Association of polymorphisms in FADS gene with age-related changes in serum phospholipid polyunsaturated fatty acids and oxidative stress markers in middle-aged nonobese men.
2013
3
10.2147/CIA.S42096
T Tanaka
Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study.
2009
18
10.1371/journal.pgen.1000338
Donald W. Bowden
Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome
2012
6
10.1017/S0007114511003230
R A Mathias
The impact of FADS genetic variants on omega6 polyunsaturated fatty acid metabolism in African Americans
2011
1
-
Oh Yoen Kim
Fatty acid desaturase (FADS) gene polymorphisms and insulin resistance in association with serum phospholipid polyunsaturated fatty acid composition in healthy Korean men: cross-sectional study
2011
4
10.1186/1743-7075-8-24
Toshiko Tanaka
Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study.
2009
1
10.1371/journal.pgen.1000338
Rasika a Mathias
The impact of FADS genetic variants on omega-6 polyunsaturated fatty acid metabolism in African Americans.
2011
6
10.1186/1471-2156-12-50
Oh Yoen Kim
Fatty acid desaturase (FADS) gene polymorphisms and insulin resistance in association with serum phospholipid polyunsaturated fatty acid composition in healthy Korean men: cross-sectional study.
2011
5
10.1186/1743-7075-8-24
Leah G Gillingham
Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition.
2013
2
10.3945/ajcn.112.043117
T Tanaka
Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study
2009
3
10.1371/journal.pgen.1000338
Susan Sergeant
Differences in arachidonic acid levels and fatty acid desaturase ( FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome.
2011
6
10.1017/S0007114511003230
Si-Wei Li
FADS gene polymorphisms confer the risk of coronary artery disease in a Chinese Han population through the altered desaturase activities: based on high-resolution melting analysis.
2013
1
10.1371/journal.pone.0055869
Toshiko Tanaka
Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study.
2009
2
10.1371/journal.pgen.1000338
Maryam Al-Hilal
Genetic variation at the FADS1-FADS2 gene locus influences delta-5 desaturase activity and LC-PUFA proportions after fish oil supplement.
2013
2
10.1194/jlr.P032276
Maryam Al-Hilal
Genetic variation at the FADS1-FADS2 gene locus influences delta-5 desaturase activity and LC-PUFA proportions after fish oil supplement.
2013
1
10.1194/jlr.P032276
Maria Azrad
Prostatic alpha-linolenic acid (ALA) is positively associated with aggressive prostate cancer: a relationship which may depend on genetic variation in ALA metabolism.
2012
2
10.1371/journal.pone.0053104
Rasika A Mathias
The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans
2011
11
10.1186/1471-2156-12-50
Maria Azrad
Prostatic alpha-linolenic acid (ALA) is positively associated with aggressive prostate cancer: a relationship which may depend on genetic variation in ALA metabolism.
2012
1
10.1371/journal.pone.0053104
T Tanaka
Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study
2009
1
Toshiko Tanaka
Genome-Wide Association Study of Plasma Polyunsaturated Fatty Acids in the InCHIANTI Study
2009
32
10.1371/journal.pgen.1000338
Evidence compiled by the
Personal Genome Project
There are no results from the
Personal Genome Project
yet. Please come back later.
Publications listed by
Genome.gov
There are no results from
genome.gov
yet. Please come back later.
Users who share this SNP:
Genome Browser