SNP rs16892766

Basic Information
Name rs16892766
Chromosome 8
Position 116618444
Weight of evidence 65
Additional Information

Links to SNPedia

Title Summary
rs16892766 A/A Common in complete genomics
rs16892766 A/C Slight (~1.5x) increase in colorectal cancer risk
rs16892766 C/C Slight (~2x) increase in colorectal cancer risk
Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).

Publications on this SNP on the Public Library of Science:

First Author Title Year of Publication # of readers
Luis M. Real A Colorectal Cancer Susceptibility New Variant at 4q26 in the Spanish Population Identified by Genome-Wide Association Analysis 2014 2464
Lenora W. M. Loo cis-Expression QTL Analysis of Established Colorectal Cancer Risk Variants in Colon Tumors and Adjacent Normal Tissue 2012 4745
Lai Fun Thean Association of Caucasian-Identified Variants with Colorectal Cancer Risk in Singapore Chinese 2012 3268
Lina Zgaga Model Selection Approach Suggests Causal Association between 25-Hydroxyvitamin D and Colorectal Cancer 2013 2843
Iva Kirac SMAD7 Variant rs4939827 Is Associated with Colorectal Cancer Risk in Croatian Population 2013 1896
Pawel Gaj Pooled Sample-Based GWAS: A Cost-Effective Alternative for Identifying Colorectal and Prostate Cancer Risk Variants in the Polish Population 2012 4915
Shuo Jiao Genome-Wide Search for Gene-Gene Interactions in Colorectal Cancer 2012 3899
Alan M. Pittman Allelic Variation at the 8q23.3 Colorectal Cancer Risk Locus Functions as a Cis-Acting Regulator of EIF3H 2010 6141
Madelyn M. Gerber Evaluation of Allele-Specific Somatic Changes of Genome-Wide Association Study Susceptibility Alleles in Human Colorectal Cancers 2012 2469
Janelle M. Hoskins Association of Eleven Common, Low-Penetrance Colorectal Cancer Susceptibility Genetic Variants at Six Risk Loci with Clinical Outcome 2012 2433
Jane C. Figueiredo Genome-Wide Diet-Gene Interaction Analyses for Risk of Colorectal Cancer 2014 17919
Mine S. Cicek Colorectal Cancer Linkage on Chromosomes 4q21, 8q13, 12q24, and 15q22 2012 3738
Linda T. Hiraki Joint Effects of Colorectal Cancer Susceptibility Loci, Circulating 25-Hydroxyvitamin D and Risk of Colorectal Cancer 2014 1795
Eva J. A. Morris A Retrospective Observational Study of the Relationship between Single Nucleotide Polymorphisms Associated with the Risk of Developing Colorectal Cancer and Survival 2015 1498
Jizhun Zhang Use of Genome-Wide Association Studies for Cancer Research and Drug Repositioning 2015 3552
Anna AbulĂ­ Genetic Variants Associated with Colorectal Adenoma Susceptibility 2016 1523

Publications on this SNP on Mendeley

First Author Title Pub. Year # of Readers DOI
I P Tomlinson A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3 2008 12 10.1038/ng.111Oa logo
Bente a Talseth-Palmer Combined analysis of three Lynch syndrome cohorts confirms the modifying effects of 8q23.3 and 11q23.1 in MLH1 mutation carriers. 2013 2 10.1002/ijc.27843Oa logo
Ian Tomlinson A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. 2008 1 10.1038/ng.111Oa logo
Iva Kirac SMAD7 Variant rs4939827 Is Associated with Colorectal Cancer Risk in Croatian Population. 2013 1 doi: 10.1371/journal.pone.0074042Oa logo
I P M Tomlinson A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. 2008 60 10.1038/ng.111
Carolyn M Hutter Characterization of gene-environment interactions for colorectal cancer susceptibility loci. 2012 12 10.1158/0008-5472.CAN-11-4067
K Hemminki A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3 2008 2 Oa logo
Ian P M Tomlinson A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. 2008 1 10.1038/ng.111Oa logo
Steven J Lubbe Relationship between 16 susceptibility loci and colorectal cancer phenotype in 3146 patients. 2012 4 10.1093/carcin/bgr243
I P Tomlinson A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3 2008 1 Oa logo
Ian P Tomlinson A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. 2008 14 10.1038/ng.111Oa logo
Juul T. Wijnen Chromosome 8q23.3 and 11q23.1 Variants Modify Colorectal Cancer Risk in Lynch Syndrome 2009 7 10.1053/j.gastro.2008.09.033
J Li Microscale heterogeneous boiling on smooth surfaces—from bubble nucleation to bubble dynamics 2005 10 10.1016/j.ijheatmasstransfer.2005.05.022
Ian P M Tomlinson A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. 2008 9 10.1038/ng.111Oa logo
I P Tomlinson A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3 2008 17 ng.111 [pii]\r10.1038/ng.111
Ian Tomlinson A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3 2008 1 10.1038/ng.111Oa logo

Evidence compiled by the Personal Genome Project

There are no results from the Personal Genome Project yet. Please come back later.

Publications listed by Genome.gov

First Author Title Journal Publication Date Trait p-value Confidence Interval
Tomlinson IP A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet 03/30/2008 Colorectal cancer 3.0e-18 [1.20-1.34]

Users who share this SNP:

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