openSNP | rs1570360

Links to SNPedia

Title	Summary
rs1570360 G/G	Normal
rs1570360 A/A	3x risk
rs1570360 A/G	3x risk

Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).

Publications on this SNP on the Public Library of Science:

First Author	Title	Year of Publication	# of readers
Daniela Ruggiero	Genetics of VEGF Serum Variation in Human Isolated Populations of Cilento: Importance of VEGF Polymorphisms	2011	4005
Ling Lin	Four Common Vascular Endothelial Growth Factor Polymorphisms (−2578C>A, −460C>T, +936C>T, and +405G>C) in Susceptibility to Lung Cancer: A Meta-Analysis	2013	2259
Montserrat García-Closas	Large-Scale Evaluation of Candidate Genes Identifies Associations between VEGF Polymorphisms and Bladder Cancer Risk	2007	7085
Christopher Ricketts	Analysis of Germline Variants in CDH1, IGFBP3, MMP1, MMP3, STK15 and VEGF in Familial and Sporadic Renal Cell Carcinoma	2009	4248
Helen R. Griffin	Genetic Variation in VEGF Does Not Contribute Significantly to the Risk of Congenital Cardiovascular Malformation	2009	4277
Montserrat García-Closas	Large-Scale Evaluation of Candidate Genes Identifies Associations between VEGF Polymorphisms and Bladder Cancer Risk	2007	8386
Gallen Triana-Baltzer	Predictive Markers of Efficacy for an Angiopoietin-2 Targeting Therapeutic in Xenograft Models	2013	1832
Daye Cheng	Vascular Endothelial Growth Factor +936C/T, –634G/C, –2578C/A, and –1154G/A Polymorphisms with Risk of Preeclampsia: A Meta-Analysis	2013	2444
Young Seok Park	The Role of VEGF and KDR Polymorphisms in Moyamoya Disease and Collateral Revascularization	2012	3314
Ellen Iacobaeus	The Expression of VEGF-A Is Down Regulated in Peripheral Blood Mononuclear Cells of Patients with Secondary Progressive Multiple Sclerosis	2011	3815
Helen R. Griffin	Genetic Variation in VEGF Does Not Contribute Significantly to the Risk of Congenital Cardiovascular Malformation	2009	3494
Linda M. Dong	An Analysis of Growth, Differentiation and Apoptosis Genes with Risk of Renal Cancer	2009	4015
Xinghua Xu	Association of VEGF Genetic Polymorphisms with Recurrent Spontaneous Abortion Risk: A Systematic Review and Meta-Analysis	2015	3049
Bhaskari Janardhan	Investigating impact of Vascular Endothelial Growth Factor Polymorphisms in Epithelial Ovarian Cancers: A Study in the Indian Population	2015	2000
Shu-Mei Yang	Joint Effect of Urinary Total Arsenic Level and VEGF-A Genetic Polymorphisms on the Recurrence of Renal Cell Carcinoma	2015	1431
Helen R. Griffin	Genetic Variation in VEGF Does Not Contribute Significantly to the Risk of Congenital Cardiovascular Malformation	2009	4294
Agnieszka Paradowska-Gorycka	Relationship between VEGF Gene Polymorphisms and Serum VEGF Protein Levels in Patients with Rheumatoid Arthritis	2016	2124
Neneng Ratnasari	Difference of polymorphism VEGF-gene rs699947 in Indonesian chronic liver disease population	2017	901
Wassim Y Almawi	Analysis of VEGFA Variants and Changes in VEGF Levels Underscores the Contribution of VEGF to Polycystic Ovary Syndrome	2016	1272
José Inácio Salles	Vascular Endothelial Growth Factor Receptor-2 Polymorphisms Have Protective Effect against the Development of Tendinopathy in Volleyball Athletes	2016	1432
Jing Zhao	A functional variant in the 3ˈ-UTR of VEGF predicts the 90-day outcome of ischemic stroke in Chinese patients	2017	1201

Publications on this SNP on Mendeley

First Author	Title	Pub. Year	# of Readers	DOI
Y Z Li	Vascular endothelial growth factor gene polymorphisms contribute to the risk of endometriosis: an updated systematic review and meta-analysis of 14 case-control studies.	2013	1	10.4238/2013.April.2.20
R Fernández-Santiago	Possible gender-dependent association of vascular endothelial growth factor (VEGF) gene and ALS.	2006	1	10.1212/01.wnl.0000219756.71928.25
Blanca Rueda	Association between functional haplotypes of vascular endothelial growth factor and renal complications in Henoch-Schönlein purpura.	2006	3	-
Mei-Tsz Su	Association of polymorphisms/haplotypes of the genes encoding vascular endothelial growth factor and its KDR receptor with recurrent pregnancy loss.	2011	2	-
Norman E Buroker	VEGFA SNPs and transcriptional factor binding sites associated with high altitude sickness in Han and Tibetan Chinese at the Qinghai-Tibetan Plateau.	2013	1	10.1007/s12576-013-0257-8
L Rodríguez-Rodríguez	Vascular endothelial growth factor A and cardiovascular disease in rheumatoid arthritis patients.	2011	4	10.1111/j.1399-0039.2010.01625.x
Rachel M Freathy	Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population.	2006	4
S K Anderson	Single nucleotide polymorphisms (SNPs) and circulating endothelial cells (CECs) as outcome predictors in patients (pts) with recurrent glioblastoma (rGBM) treated with bevacizumab (BEV) and sorafenib (SOR)	2011	1
Idalia Garza-Veloz	No association between polymorphisms/haplotypes of the vascular endothelial growth factor gene and preeclampsia.	2011	1	10.1186/1471-2393-11-35
R Fernández-Santiago	Possible gender-dependent association of vascular endothelial growth factor (VEGF) gene and ALS.	2006	5	10.1212/01.wnl.0000219756.71928.25
Rachel M Freathy	Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population.	2006	3
Sara Landgren	No association of VEGF polymorphims with Alzheimer's disease.	2010	4	10.1007/s12017-009-8096-8
Xiuye Xing	Association of vascular endothelial growth factor gene polymorphisms with recurrent spontaneous abortion in Chinese Han women.	2011	0	10.1111/j.1600-0897.2010.00924.x
A J Churchill	VEGF polymorphisms are associated with severity of diabetic retinopathy	2008	3	iovs.07-1383 [pii]\r10.1167/iovs.07-1383
Mei-Tsz Su	Association of polymorphisms/haplotypes of the genes encoding vascular endothelial growth factor and its KDR receptor with recurrent pregnancy loss.	2011	4	10.1093/humrep/deq401
Blanca Rueda	A functional variant of vascular endothelial growth factor is associated with severe ischemic complications in giant cell arteritis.	2005	3
Jae Wook Yang	Gene polymorphism of vascular endothelial growth factor -1154 G>A is associated with hypertensive nephropathy in a Hispanic population.	2011	4	-
Jun Xie	VEGF C-634G polymorphism is associated with protection from isolated ventricular septal defect: case-control and TDT studies.	2007	1	-
R.J. Motzer	81 Updated results of the phase 3 AXIS trial: Axitinib vs sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC)	2012	4	10.1016/S1569-9056(12)60080-3
Heba H Al-Habboubi	Contribution of VEGF polymorphisms to variation in VEGF serum levels in a healthy population.	2011	1	-
B Rueda	Analysis of vascular endothelial growth factor (VEGF) functional variants in rheumatoid arthritis	2005	1	S0198-8859(05)00102-3 [pii]; 10.1016/j.humimm.2005.05.004 [doi]
B Rueda	Association between functional haplotypes of vascular endothelial growth factor and renal complications in Henoch-Schonlein purpura	2006	1	0315162X-33-69 [pii]
Xiaopan Wu	Polymorphisms in the VEGFA promoter are associated with susceptibility to hepatocellular carcinoma by altering promoter activity.	2013	2	10.1002/ijc.28109
Sara Landgren	No association of VEGF polymorphims with Alzheimer's disease.	2010	2	-
Yang Chen	The RTK/ERK pathway is associated with prostate cancer risk on the SNP level: A pooled analysis of 41 sets of data from case-control studies	2014	3	10.1016/j.gene.2013.10.042
K Masago	Effect of vascular endothelial growth factor polymorphisms on survival in advanced-stage non-small-cell lung cancer	2009	1	-
S Lazzeri	VEGF-A polymorphisms predict short-term functional response to intravitreal ranibizumab in exudative age-related macular degeneration	2013	3	http://dx.doi.org/10.2217/pgs.13.43
Amanda J. Churchill	VEGF Polymorphisms Are Associated with Severity of Diabetic Retinopathy	2008	1	10.1167/iovs.07-1383
Norman E Buroker	VEGFA SNPs and transcriptional factor binding sites associated with high altitude sickness in Han and Tibetan Chinese at the Qinghai-Tibetan Plateau.	2013	1	10.1007/s12576-013-0257-8
Helen R Griffin	Genetic variation in VEGF does not contribute significantly to the risk of congenital cardiovascular malformation.	2009	8	10.1371/journal.pone.0004978
Amanda J Churchill	VEGF polymorphisms are associated with severity of diabetic retinopathy.	2008	8	10.1167/iovs.07-1383
Gordana Supic	Association of VEGF-A genetic polymorphisms with cancer risk and survival in advanced-stage oral squamous cell carcinoma patients.	2012	1	10.1016/j.oraloncology.2012.05.023
Blanca Rueda	Analysis of vascular endothelial growth factor (VEGF) functional variants in rheumatoid arthritis.	2005	2	-
G Supic	Association of VEGF-A genetic polymorphisms with cancer risk and survival in advanced-stage oral squamous cell carcinoma patients	2012	1	-
Juan Francisco Calderón	VEGFA polymorphisms and cardiovascular anomalies in 22q11 microdeletion syndrome: a case-control and family-based study.	2009	6	10.4067/S0716-97602009000400007
Hebah H Al-Habboubi	The relation of vascular endothelial growth factor (VEGF) gene polymorphisms on VEGF levels and the risk of vasoocclusive crisis in sickle cell disease.	2012	1	10.1111/ejh.12003
Katsuhiro Masago	Vascular endothelial growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer: a review of recent clinical trials.	2007	3	-
L Rodríguez-Rodríguez	Vascular endothelial growth factor A and cardiovascular disease in rheumatoid arthritis patients.	2011	6	10.1111/j.1399-0039.2010.01625.x
A J Churchill	VEGF polymorphisms are associated with severity of diabetic retinopathy	2008	1	-
Heba H Al-Habboubi	Contribution of VEGF polymorphisms to variation in VEGF serum levels in a healthy population.	2011	1	-
A J Cologna	VEGF genetic polymorphisms affect the responsiveness to sildenafil in clinical and postoperative erectile dysfunction	2012	1	10.1038/tpj.2012.39
Xiuye Xing	Association of vascular endothelial growth factor gene polymorphisms with recurrent spontaneous abortion in Chinese Han women.	2011	1	10.1111/j.1600-0897.2010.00924.x
Jesus Garcia-Donas	Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study.	2011	0
Xiaopan Wu	Polymorphisms in the VEGFA promoter are associated with susceptibility to hepatocellular carcinoma by altering promoter activity.	2013	3	10.1002/ijc.28109
Min-Young Chun	Association of vascular endothelial growth factor polymorphisms with nonproliferative and proliferative diabetic retinopathy.	2010	2	10.1210/jc.2009-2719
Blanca Rueda	Analysis of vascular endothelial growth factor (VEGF) functional variants in rheumatoid arthritis.	2005	1	10.1016/j.humimm.2005.05.004
Xiuye Xing	Association of vascular endothelial growth factor gene polymorphisms with recurrent spontaneous abortion in Chinese Han women.	2011	0	10.1111/j.1600-0897.2010.00924.x
L Rodriguez-Rodriguez	Vascular endothelial growth factor A and cardiovascular disease in rheumatoid arthritis patients	2011	3
Blanca Rueda	Association between functional haplotypes of vascular endothelial growth factor and renal complications in Henoch-Schönlein purpura.	2006	2
Blanca Rueda	A functional variant of vascular endothelial growth factor is associated with severe ischemic complications in giant cell arteritis.	2005	3	-
Jun Xie	VEGF C-634G polymorphism is associated with protection from isolated ventricular septal defect: case-control and TDT studies.	2007	2	10.1038/sj.ejhg.5201890
L P Zhou	Vascular endothelial growth factor gene polymorphisms and colorectal cancer risk: a meta-analysis.	2011	3	10.4238/2011.October.31.13
Juan Francisco Calderón	VEGFA polymorphisms and cardiovascular anomalies in 22q11 microdeletion syndrome: a case-control and family-based study.	2009	5
Yoo-Jin Shin	Association between promoter polymorphisms of vascular endothelial growth factor gene and sporadic Alzheimer's disease among Northern Chinese Han.	2010	0

Evidence compiled by the Personal Genome Project

There are no results from the Personal Genome Project yet. Please come back later.

Publications listed by Genome.gov

There are no results from genome.gov yet. Please come back later.

Name	rs1570360
Chromosome	6
Position	43770093
Weight of evidence	111

SNP rs1570360

Basic Information

Genotype Frequency

Allele Frequency

Additional Information

Links to SNPedia

Publications on this SNP on the Public Library of Science:

Publications on this SNP on Mendeley

Evidence compiled by the Personal Genome Project

Publications listed by Genome.gov

Users who share this SNP:

Genome Browser

Contacts