openSNP | rs12248560

Links to SNPedia

Title	Summary
rs12248560 C/T	*Cyp2c1917 ultra fast metabolizer; drug metabolism effects; also 0.77x decreased breast cancer risk**
rs12248560 C/C	Normal
rs12248560 T/T	*Cyp2c1917 ultra fast metabolizer; drug metabolism effects; also 0.77x decreased breast cancer risk**

Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).

Publications on this SNP on the Public Library of Science:

First Author	Title	Year of Publication	# of readers
Vania Bonifaz-Peña	Exploring the Distribution of Genetic Markers of Pharmacogenomics Relevance in Brazilian and Mexican Populations	2014	5202
Dong-Yi Chen	Paraoxonase-1 Is Not a Major Determinant of Stent Thrombosis in a Taiwanese Population	2012	2329
Jeffrey J. W. Verschuren	Systematic Testing of Literature Reported Genetic Variation Associated with Coronary Restenosis: Results of the GENDER Study	2012	2110
Jolanta M. Siller-Matula	Interplay between Genetic and Clinical Variables Affecting Platelet Reactivity and Cardiac Adverse Events in Patients Undergoing Percutaneous Coronary Intervention	2014	2482
Luciana Kase Tanno	The Absence of CYP3A5*3 Is a Protective Factor to Anticonvulsants Hypersensitivity Reactions: A Case-Control Study in Brazilian Subjects	2015	1797
Guigao Lin	Implementation of Cell Samples as Controls in National Proficiency Testing for Clopidogrel Therapy-Related CYP2C19 Genotyping in China: A Novel Approach	2015	1323
Xiao-Qing Li	Association of PON1, P2Y12 and COX1 with Recurrent Ischemic Events in Patients with Extracranial or Intracranial Stenting	2016	2200
Alexandra Audemard-Verger	Glutathione S Transferases Polymorphisms Are Independent Prognostic Factors in Lupus Nephritis Treated with Cyclophosphamide	2016	1678
Cosmin Sebastian Voican	Liver Function Test Abnormalities in Depressed Patients Treated with Antidepressants: A Real-World Systematic Observational Study in Psychiatric Settings	2016	4124
Liuh Ling Goh	Analysis of Genetic Variation in CYP450 Genes for Clinical Implementation	2017	3647
Clint Mizzi	A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics	2016	5128
Mariana S. Silva-Alves	A Prediction Algorithm for Drug Response in Patients with Mesial Temporal Lobe Epilepsy Based on Clinical and Genetic Information	2017	2889
Geik Yong Ang	Detection of CYP2C19 Genetic Variants in Malaysian Orang Asli from Massively Parallel Sequencing Data	2016	1510

Publications on this SNP on Mendeley

First Author	Title	Pub. Year	# of Readers	DOI
Yan Shi	Analysis of 50 SNPs in CYP2D6, CYP2C19, CYP2C9, CYP3A4 and CYP1A2 by MALDI-TOF mass spectrometry in Chinese Han population.	2011	14	10.1016/j.forsciint.2011.04.001
Christina Justenhoven	RCAS1 is associated with ductal breast cancer progression.	2002	5	-
Christina Justenhoven	CYP2C19*17 is associated with decreased breast cancer risk.	2009	3	10.1007/s10549-008-0076-4
Llewellyn D Spargo	Polymorphisms in cytochrome P450 2C19 enzyme and cessation of leflunomide in patients with rheumatoid arthritis	2012	1	10.1186/ar3911
C Justenhoven	CYP2C19*17 is associated with decreased breast cancer risk	2009	2

Evidence compiled by the Personal Genome Project

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Publications listed by Genome.gov

There are no results from genome.gov yet. Please come back later.

Name	rs12248560
Chromosome	10
Position	94761900
Weight of evidence	46

SNP rs12248560

Basic Information

Genotype Frequency

Allele Frequency

Additional Information

Links to SNPedia

Publications on this SNP on the Public Library of Science:

Publications on this SNP on Mendeley

Evidence compiled by the Personal Genome Project

Publications listed by Genome.gov

Users who share this SNP:

Genome Browser

Contacts