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SNP rs1219648
Basic Information
Name
rs1219648
Chromosome
10
Position
121586676
Weight of evidence
79
Genotype Frequency
AA
AG
GG
TT
36%
48%
16%
Allele Frequency
A
T
G
C
60%
40%
Additional Information
SNPedia (3)
PLoS (10)
Mendeley (38)
Personal Genome Project (0)
Genome.gov (3)
Other users (1721)
Comments (0)
Links to SNPedia
Title
Summary
rs1219648 G/G
1.64x risk for breast cancer
rs1219648 A/G
1.20x risk for breast cancer
rs1219648 A/A
No summary provided.
Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).
Publications on this SNP on the Public Library of Science:
First Author
Title
Year of Publication
# of readers
Chen Zhang
A Novel Multiplex Tetra-Primer ARMS-PCR for the Simultaneous Genotyping of Six Single Nucleotide Polymorphisms Associated with Female Cancers
2013
9074
Sarah Siddiqui
A Study on Genetic Variants of Fibroblast Growth Factor Receptor 2 (
FGFR2
) and the Risk of Breast Cancer from North India
2014
1756
Jie Ge
The
GSTP1 105Val
Allele Increases Breast Cancer Risk and Aggressiveness but Enhances Response to Cyclophosphamide Chemotherapy in North China
2013
1790
Rosemary Braun
Pathways of Distinction Analysis: A New Technique for Multi–SNP Analysis of GWAS Data
2011
13772
Siew-Kee Low
Genome-Wide Association Study of Breast Cancer in the Japanese Population
2013
4218
Yadav Sapkota
Identification of a Breast Cancer Susceptibility Locus at 4q31.22 Using a Genome-Wide Association Study Paradigm
2013
3322
Jirong Long
Evaluating Genome-Wide Association Study-Identified Breast Cancer Risk Variants in African-American Women
2013
4523
Samuel P. Dickson
Rare Variants Create Synthetic Genome-Wide Associations
2010
43735
Xia Jiang
A Bayesian Method for Evaluating and Discovering Disease Loci Associations
2011
3088
Lin Zhao
The Association between ATM IVS 22-77 T>C and Cancer Risk: A Meta-Analysis
2012
2796
Publications on this SNP on Mendeley
First Author
Title
Pub. Year
# of Readers
DOI
Jill S Barnholtz-Sloan
FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women
2010
11
10.1093/carcin/bgq128
Leon Raskin
FGFR2 is a breast cancer susceptibility gene in Jewish and Arab Israeli populations.
2008
6
-
D J Hunter
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
2007
0
ng2075 [pii]\r10.1038/ng2075
Shaneda Warren Andersen
Breast cancer susceptibility associated with rs1219648 (fibroblast growth factor receptor 2) and postmenopausal hormone therapy use in a population-based United States study.
2013
0
D J Hunter
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
2007
0
Wei Zheng
Genetic and clinical predictors for breast cancer risk assessment and stratification among Chinese women.
2010
16
10.1093/jnci/djq170
Wei Zheng
Evaluation of 11 breast cancer susceptibility loci in African-American women.
2009
0
10.1158/1055-9965.EPI-09-0624
D J Hunter
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
2007
5
10.1038/ng2075
Sharon N Teraoka
Single nucleotide polymorphisms associated with risk for contralateral breast cancer in the Women's Environment, Cancer, and Radiation Epidemiology (WECARE) Study
2011
7
10.1186/bcr3057
Margaret A Gates
Breast cancer susceptibility alleles and ovarian cancer risk in 2 study populations.
2009
2
-
David Hunter
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
2007
1
10.1038/ng2075
E C Küchler
Tooth Agenesis Association with Self-reported Family History of Cancer
2013
1
10.1177/0022034512468750
Wei Zheng
Evaluation of 11 breast cancer susceptibility loci in African-American women
2009
1
10.1158/1055-9965.EPI-09-0624
Wei Zheng
Evaluation of 11 Breast Cancer Susceptibility Loci in African-American Women
2009
0
10.1158/1055-9965.EPI-09-0624
A. J. Swerdlow
FGFR2 genotype and risk of radiation-associated breast cancer in Hodgkin lymphoma
2012
0
10.1182/blood-2011-10-383380
D J Hunter
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
2007
25
ng2075 [pii]\r10.1038/ng2075
Shaneda Warren Andersen
Breast cancer susceptibility associated with rs1219648 (fibroblast growth factor receptor 2) and postmenopausal hormone therapy use in a population-based United States study.
2013
1
-
David J Hunter
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.
2007
0
Yussanne P. Ma
FGFR2 genotype and risk of radiation-associated breast cancer in Hodgkin lymphoma
2012
4
10.1182/blood-2011-10-383380
DJ Hunter
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.
2007
0
10.1038/ng2075
Simon Stacey
Finding needles in a haystack
2007
16
10.1038/ng2075
D J Hunter
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
2007
0
10.1038/ng2075
S W Andersen
Breast cancer susceptibility associated with rs1219648 (fibroblast growth factor receptor 2) and postmenopausal hormone therapy use in a population-based United States study
2013
2
-
W Zheng
Evaluation of 11 breast cancer susceptibility loci in African-American women
2009
0
1055-9965.EPI-09-0624 [pii]\r10.1158/1055-9965.EPI-09-0624
Catalin Marian
FGFR2 intronic SNPs and breast cancer risk: associations with tumor characteristics and interactions with exogenous exposures and other known breast cancer risk factors.
2011
0
10.1002/ijc.25686
Catalin Marian
FGFR2 intronic SNPs and breast cancer risk: associations with tumor characteristics and interactions with exogenous exposures and other known breast cancer risk factors.
2011
6
10.1002/ijc.25686
David J Hunter
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
2007
0
10.1038/ng2075
David J Hunter
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.
2007
0
10.1038/ng2075
E C Küchler
Tooth agenesis association with self-reported family history of cancer.
2013
0
10.1177/0022034512468750
D J Hunter
<<<<duplicate>>>A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
2007
0
ng2075 [pii]\n10.1038/ng2075
Leon Raskin
FGFR2 is a breast cancer susceptibility gene in Jewish and Arab Israeli populations.
2008
0
10.1158/1055-9965.EPI-08-0018
David J Hunter
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.
2007
0
10.1038/ng2075
David J Hunter
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.
2007
8
10.1038/ng2075
S W Andersen
Breast cancer susceptibility associated with rs1219648 (fibroblast growth factor receptor 2) and postmenopausal hormone therapy use in a population-based United States study
2013
1
-
Xiao-Hui Chen
Risk of aggressive breast cancer in women of Han nationality carrying TGFB1 rs1982073 C allele and FGFR2 rs1219648 G allele in North China.
2011
2
-
Jill S Barnholtz-Sloan
Replication of GWAS "Hits" by Race for Breast and Prostate Cancers in European Americans and African Americans.
2011
7
10.3389/fgene.2011.00037
David J Hunter
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.
2007
80
-
Martha L Slattery
Replication of five GWAS-identified loci and breast cancer risk among Hispanic and non-Hispanic white women living in the Southwestern United States.
2011
7
-
Evidence compiled by the
Personal Genome Project
There are no results from the
Personal Genome Project
yet. Please come back later.
Publications listed by
Genome.gov
First Author
Title
Journal
Publication Date
Trait
p-value
Confidence Interval
Li J
A combined analysis of genome-wide association studies in breast cancer.
Breast Cancer Res Treat
09/26/2010
Breast cancer
2.0e-13
[1.22-1.42]
Hunter DJ
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.
Nat Genet
05/27/2007
Breast cancer
1.0e-10
[1.07-1.42]
Fletcher O
Novel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study.
J Natl Cancer Inst
01/24/2011
Breast cancer
1.0e-30
[1.25-1.37]
Users who share this SNP:
Genome Browser
Human GrCh38/hg38
