openSNP | rs1205

SNP rs1205

Basic Information

Name	rs1205
Chromosome	1
Position	159712443
Weight of evidence	139

Links to SNPedia

Title	Summary
rs1205 C/T	Common in complete genomics

Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).

Publications on this SNP on the Public Library of Science:

First Author	Title	Year of Publication	# of readers
Anne E Hughes	Neovascular Age-Related Macular Degeneration Risk Based on CFH, LOC387715/HTRA1, and Smoking	2007	7679
Jennifer K. Pai	C-Reactive Protein (CRP) Gene Polymorphisms, CRP Levels, and Risk of Incident Coronary Heart Disease in Two Nested Case-Control Studies	2008	8719
Raymond Schuch	Use of a Bacteriophage Lysin to Identify a Novel Target for Antimicrobial Development	2013	16072
Anubha Mahajan	Common Variants in CRP and LEPR Influence High Sensitivity C-Reactive Protein Levels in North Indians	2011	2123
Lyle G. Best	Two Variants of the C-Reactive Protein Gene Are Associated with Risk of Pre-Eclampsia in an American Indian Population	2013	3357
Simon P. Mooijaart	C-Reactive Protein and Genetic Variants and Cognitive Decline in Old Age: The PROSPER Study	2011	2965
Laura Ibáñez	HIV-Infection, Atherosclerosis and the Inflammatory Pathway: Candidate Gene Study in a Spanish HIV-Infected Population	2014	1872
Hai-Xiang Su	Mutations of C-Reactive Protein (CRP) -286 SNP, APC and p53 in Colorectal Cancer: Implication for a CRP-Wnt Crosstalk	2014	4528
Sebastian Okser	Genetic Variants and Their Interactions in the Prediction of Increased Pre-Clinical Carotid Atherosclerosis: The Cardiovascular Risk in Young Finns Study	2010	8490
Nadimuthu Vinayagamoorthy	New Variants Including ARG1 Polymorphisms Associated with C-Reactive Protein Levels Identified by Genome-Wide Association and Pathway Analysis	2014	3394
Silvia Naitza	A Genome-Wide Association Scan on the Levels of Markers of Inflammation in Sardinians Reveals Associations That Underpin Its Complex Regulation	2012	10101
Mika Kivimäki	Does High C-reactive Protein Concentration Increase Atherosclerosis? The Whitehall II Study	2008	7017
Eric J Brunner	Inflammation, Insulin Resistance, and Diabetes—Mendelian Randomization Using CRP Haplotypes Points Upstream	2008	16644
Benjamin Rhodes	A Genetic Association Study of Serum Acute-Phase C-Reactive Protein Levels in Rheumatoid Arthritis: Implications for Clinical Interpretation	2010	8032
Zhihong Gong	Innate Immunity Pathways and Breast Cancer Risk in African American and European-American Women in the Women’s Circle of Health Study (WCHS)	2013	2609
Debbie A. Lawlor	The Association of C-Reactive Protein and CRP Genotype with Coronary Heart Disease: Findings from Five Studies with 4,610 Cases amongst 18,637 Participants	2008	5753

Publications on this SNP on Mendeley

First Author	Title	Pub. Year	# of Readers	DOI
Osvaldo P Almeida	Polymorphisms of the CRP gene inhibit inflammatory response and increase susceptibility to depression: the Health in Men Study.	2009	8	10.1093/ije/dyp199
A Morita	Association study between C-reactive protein genes and ischemic stroke in Japanese subjects	2006	1	S0895-7061(06)00043-4 [pii]\r10.1016/j.amjhyper.2005.11.015
Qi Wang	C-reactive protein polymorphisms and genetic susceptibility to ischemic stroke and hemorrhagic stroke in the Chinese Han population.	2009	2	10.1038/aps.2009.14
E Flores-Alfaro	Common variants in the CRP gene are associated with serum C-reactive protein levels and body mass index in healthy individuals in Mexico.	2012	1	-
Lyle G Best	Genetic Variants, Immune Function, and Risk of Pre-Eclampsia among American Indians.	2011	2	10.1111/j.1600-0897.2011.01076.x
Miao Hu	Effect of central obesity, low high-density lipoprotein cholesterol and C-reactive protein polymorphisms on C-reactive protein levels during treatment with Rosuvastatin (10 mg Daily).	2010	1	-
Lucia A Hindorff	Common variants in the CRP gene in relation to longevity and cause-specific mortality in older adults: the Cardiovascular Health Study.	2008	6	10.1016/j.atherosclerosis.2007.08.012
A M Hung	CRP polymorphisms and progression of chronic kidney disease in African Americans	2010	2	CJN.01900309 [pii]\n10.2215/CJN.01900309
Lyle G Best	Two variants of the C-reactive protein gene are associated with risk of pre-eclampsia in an american Indian population.	2013	2	10.1371/journal.pone.0071231
I K Kim	Comprehensive analysis of CRP, CFH Y402H and environmental risk factors on risk of neovascular age-related macular degeneration	2008	2
J Sunyer	Systemic inflammation, genetic susceptibility and lung function.	2008	6	10.1183/09031936.00052507
T Mölkänen	Genetic polymorphism of the C-reactive protein (CRP) gene and a deep infection focus determine maximal serum CRP level in Staphylococcus aureus bacteremia.	2010	5	10.1007/s10096-010-0978-z
E Flores-Alfaro	Common variants in the CRP gene are associated with serum C-reactive protein levels and body mass index in healthy individuals in Mexico.	2012	1	10.4238/2012.May.14.5
F-H Lin	Combined effect of C-reactive protein gene SNP +2147 A/G and interleukin-6 receptor gene SNP rs2229238 C/T on anthropometric characteristics among school children in Taiwan.	2011	1	-
Christine G St Germaine	Genetic polymorphisms and the cardiovascular risk of non-steroidal anti-inflammatory drugs.	2010	4	10.1016/j.amjcard.2010.01.352
C G St Germaine	Genetic polymorphisms and the cardiovascular risk of non-steroidal anti-inflammatory drugs	2010	1	-
Martha L Slattery	Genetic variation in C-reactive protein in relation to colon and rectal cancer risk and survival.	2011	1	10.1002/ijc.25721
Martha L Slattery	Genetic variation in C-reactive protein in relation to colon and rectal cancer risk and survival.	2010	2	10.1002/ijc.25721
M L Slattery	Genetic variation in C-reactive protein in relation to colon and rectal cancer risk and survival.	2011	1
Qi Wang	C-reactive protein polymorphisms and genetic susceptibility to ischemic stroke and hemorrhagic stroke in the Chinese Han population.	2009	2	-
Charlotte E Bolton	The CRP genotype, serum levels and lung function in men: the Caerphilly Prospective Study.	2011	4	10.1042/CS20100504
Christine G St Germaine	Genetic polymorphisms and the cardiovascular risk of non-steroidal anti-inflammatory drugs.	2010	1	-
Zhihong Gong	Innate Immunity Pathways and Breast Cancer Risk in African American and European-American Women in the Women's Circle of Health Study (WCHS).	2013	2	10.1371/journal.pone.0072619
L G Best	Genetic Variants, Immune Function, and Risk of Pre-Eclampsia among American Indians	2012	1	DOI 10.1111/j.1600-0897.2011.01076.x
Shaoyong Su	Pleiotropy of C-reactive protein gene polymorphisms with C-reactive protein levels and heart rate variability in healthy male twins.	2009	0
Mika Kivimäki	Does High C-reactive Protein Concentration Increase Atherosclerosis? The Whitehall II Study	2008	0	10.1371/journal.pone.0003013
Wiebke Schumacher	Association between C-reactive protein genotype, circulating levels, and aortic pulse wave velocity.	2009	11	10.1161/HYPERTENSIONAHA.108.117622
Vincent E Friedewald	AJC Editor's consensus: Selective and nonselective nonsteroidal anti-inflammatory drugs and cardiovascular risk.	2010	12	-
María José Martínez-Calatrava	Common haplotypes of the C-reactive protein gene and circulating leptin levels influence the interindividual variability in serum C-reactive protein levels. The Segovia study.	2007	0	10.1160/TH07-03-0231
Jian Shen	Association of common C-reactive protein (CRP) gene polymorphisms with baseline plasma CRP levels and fenofibrate response: the GOLDN study.	2008	0
M Hu	Determinants of hsCRP levels in Chinese patients treated with rosuvastatin	2010	2	-
Darya Gaysina	Association between adolescent emotional problems and metabolic syndrome: the modifying effect of C-reactive protein gene (CRP) polymorphisms.	2011	1	-
Akihiko Morita	Polymorphism of the C-reactive protein (CRP) gene is related to serum CRP Level and arterial pulse wave velocity in healthy elderly Japanese.	2006	4	10.1291/hypres.29.323
Cathy C. Lee	Relation of Genetic Variation in the Gene Coding for C-Reactive Protein with Its Plasma Protein Concentrations: Findings from the Women's Health Initiative Observational Cohort	2009	1	10.1373/clinchem.2008.117176
Rogelio Palomino-Morales	C-reactive protein gene polymorphisms in biopsy-proven giant cell arteritis from Northwestern Spain.	2009	1	10.3899/jrheum.080707
L G Best	Genetic variants, immune function, and risk of pre-eclampsia among American Indians	2012	1	10.1111/j.1600-0897.2011.01076.x
B. Stork, G.; Ganem	a-Silylated Vinyl Ketones. A New Class of Reagents for the Annelation of Ketones	1973	3	10.1245/s10434-011-1575-9
J Sunyer	Systemic inflammation, genetic susceptibility and lung function.	2008	5	10.1183/09031936.00052507
Satoru Motoyama	Evaluation of the Risk of Lymph Node Metastasis Using CRP 1846C > T Genetic Polymorphism in Submucosal Thoracic Esophageal Squamous Cell Carcinoma	2013	1	10.1245/s10434-012-2765-9
Ming-Sheng Teng	Association between C-reactive protein gene haplotypes and C-reactive protein levels in Taiwanese: interaction with obesity.	2009	0	-
Indrani Halder	Polymorphisms in the CRP gene moderate an association between depressive symptoms and circulating levels of C-reactive protein	2010	15	10.1016/j.bbi.2009.09.014
Isabella Kardys	Usefulness of combining complement factor H and C-reactive protein genetic profiles for predicting myocardial infarction (from the Rotterdam Study).	2007	0
J Sunyer	Systemic inflammation, genetic susceptibility and lung function.	2008	7	-
S H Yang	Association of C-reactive protein gene polymorphisms and colorectal cancer	2011	1
Miao Hu	Effect of central obesity, low high-density lipoprotein cholesterol and C-reactive protein polymorphisms on C-reactive protein levels during treatment with Rosuvastatin (10 mg Daily).	2010	6	10.1016/j.amjcard.2010.07.044
C.G.St. Germaine	Genetic Polymorphisms and the Cardiovascular Risk of Non-Steroidal Anti-Inflammatory Drugs	2010	1	-
Darya Gaysina	Association between adolescent emotional problems and metabolic syndrome: the modifying effect of C-reactive protein gene (CRP) polymorphisms.	2011	1	-
Rogelio Palomino-Morales	C-reactive protein gene polymorphisms in biopsy-proven giant cell arteritis from Northwestern Spain.	2009	1	-
Ming Xu	Serum C-reactive protein and risk of lung cancer: a case-control study.	2013	2	10.1007/s12032-012-0319-4
A M Hung	CRP polymorphisms and progression of chronic kidney disease in African Americans	2010	1	10.2215/CJN.01900309
Ivana K Kim	Comprehensive analysis of CRP, CFH Y402H and environmental risk factors on risk of neovascular age-related macular degeneration.	2008	5
Terhi Kettunen	Polymorphism in the C-reactive protein (CRP) gene affects CRP levels in plasma and one early marker of atherosclerosis in men: The Health 2000 Survey.	2011	0	10.3109/00365513.2011.568123
E Morales	Maternal C-reactive protein levels in pregnancy are associated with wheezing and lower respiratory tract infections in the offspring	2011	2
C C Lee	Relation of genetic variation in the gene coding for C-reactive protein with its plasma protein concentrations: findings from the Women's Health Initiative Observational Cohort	2009	1	clinchem.2008.117176 [pii]\n10.1373/clinchem.2008.117176
Stefania Ottaviani	C reactive protein and alpha1-antitrypsin: relationship between levels and gene variants.	2011	2	10.1016/j.trsl.2010.12.014
S H An	Association of gene polymorphisms with the risk of warfarin bleeding complications at therapeutic INR in patients with mechanical cardiac valves.	2014	1	10.1111/jcpt.12143
Darya Gaysina	Association between adolescent emotional problems and metabolic syndrome: the modifying effect of C-reactive protein gene (CRP) polymorphisms.	2011	0	-
María José Martínez-Calatrava	Common haplotypes of the C-reactive protein gene and circulating leptin levels influence the interindividual variability in serum C-reactive protein levels. The Segovia study.	2007	0
I K Kim	Comprehensive analysis of CRP, CFH Y402H and environmental risk factors on risk of neovascular age-related macular degeneration	2008	1
J Sunyer	Systemic inflammation, genetic susceptibility and lung function	2008	2	09031936.00052507 [pii]\r10.1183/09031936.00052507
Darya Gaysina	Association between adolescent emotional problems and metabolic syndrome: The modifying effect of C-reactive protein gene (CRP) polymorphisms	2011	10	10.1016/j.bbi.2011.01.019
Cathy Lee	Relation of Genetic Variation in the Gene Coding for C-Reactive Protein with Its Plasma Protein Concentrations: Findings from the Women's Health Initiative Observational Cohort	2009	1
Miao Hu	Effect of central obesity, low high-density lipoprotein cholesterol and C-reactive protein polymorphisms on C-reactive protein levels during treatment with Rosuvastatin (10 mg Daily).	2010	2	10.1016/j.amjcard.2010.07.044
Simona Ognjanovic	Serum CRP and IL-6, genetic variants and risk of colorectal adenoma in a multiethnic population.	2010	0
Mika Kivimäki	Does high C-reactive protein concentration increase atherosclerosis? The Whitehall II Study.	2008	23	10.1371/journal.pone.0003013
T Mölkänen	Genetic polymorphism of the C-reactive protein (CRP) gene and a deep infection focus determine maximal serum CRP level in Staphylococcus aureus bacteremia.	2010	3	-
M L Slattery	Genetic variation in C-reactive protein in relation to colon and rectal cancer risk and survival	2011	1	10.1002/ijc.25721
Xiao-Feng Tang	C-reactive protein (CRP) gene polymorphisms, CRP levels and risk of incident essential hypertension: findings from an observational cohort of Han Chinese	2012	2	10.1038/hr.2012.89
Hong Kong	C-reactive protein (CRP) gene polymorphisms, CRP levels and risk of incident essential hypertension: findings from an observational cohort of Han Chinese.	2012	0	10.1038/hr.2012.89
Jian Shen	Association of common C-reactive protein (CRP) gene polymorphisms with baseline plasma CRP levels and fenofibrate response: the GOLDN study.	2008	3	10.2337/dc07-1687
J Sunyer	Systemic inflammation, genetic susceptibility and lung function.	2008	0
E Flores-Alfaro	Common variants in the CRP gene are associated with serum C-reactive protein levels and body mass index in healthy individuals in Mexico.	2012	1	10.4238/2012.May.14.5
S H Yang	Association of C-reactive protein gene polymorphisms and colorectal cancer	2011	1
Osvaldo P Almeida	Polymorphisms of the CRP gene inhibit inflammatory response and increase susceptibility to depression: the Health in Men Study.	2009	0	10.1093/ije/dyp199
Darya Gaysina	Association between adolescent emotional problems and metabolic syndrome: the modifying effect of C-reactive protein gene (CRP) polymorphisms.	2011	1	-
R Zakharyan	Genetic variants of the inflammatory C-reactive protein and schizophrenia in Armenian population: a pilot study.	2010	0	10.1111/j.1744-313X.2010.00942.x
S H Yang	Association of C-reactive protein gene polymorphisms and colorectal cancer.	2011	1
Darya Gaysina	Association between adolescent emotional problems and metabolic syndrome: the modifying effect of C-reactive protein gene (CRP) polymorphisms.	2011	7	10.1016/j.bbi.2011.01.019
Martha L Slattery	Genetic variation in C-reactive protein in relation to colon and rectal cancer risk and survival.	2011	3	10.1002/ijc.25721
Robert Y L Zee	C-reactive protein gene variation and type 2 diabetes mellitus: a case-control study.	2008	3	10.1016/j.atherosclerosis.2007.08.013
Gerthe Veen	C-reactive protein polymorphisms are associated with the cortisol awakening response in basal conditions in human subjects.	2011	7	10.3109/10253890.2010.515273
E Morales	Maternal C-reactive protein levels in pregnancy are associated with wheezing and lower respiratory tract infections in the offspring	2011	1
Darya Gaysina	Association between adolescent emotional problems and metabolic syndrome: the modifying effect of C-reactive protein gene (CRP) polymorphisms.	2011	2	-
R Zakharyan	Genetic variants of the inflammatory C-reactive protein and schizophrenia in Armenian population: a pilot study.	2010	0	10.1111/j.1744-313X.2010.00942.x
Kaori Terata	Evaluation of the potential for lymph node metastasis using CRP 1846C>T genetic polymorphism in invasive breast cancer.	2014	1	10.1007/s13277-014-1786-3
Indrani Halder	Polymorphisms in the CRP gene moderate an association between depressive symptoms and circulating levels of C-reactive protein.	2010	8	-
E Komurcu-Bayrak	Association of C-reactive protein (CRP) gene allelic variants with serum CRP levels and hypertension in Turkish adults.	2009	2	10.1016/j.atherosclerosis.2009.03.030
Best L.	Two variants of the C-reactive protein gene are associated with risk of pre-eclampsia in an American indian population	2013	1	-
Lyle G Best	Genetic variants, immune function, and risk of pre-eclampsia among American Indians.	2012	3	10.1111/j.1600-0897.2011.01076.x
Miao Hu	Effect of central obesity, low high-density lipoprotein cholesterol and c-reactive protein polymorphisms on c-reactive protein levels during treatment with rosuvastatin (10 mg daily)	2010	7	10.1016/j.amjcard.2010.07.044
Indrani Halder	Polymorphisms in the CRP gene moderate an association between depressive symptoms and circulating levels of C-reactive protein.	2010	1	10.1016/j.bbi.2009.09.014
G Kuhlenbaeumer	Genetic variants in the C-reactive protein gene are associated with microangiopathic ischemic stroke	2010	1
E Flores-Alfaro	Common variants in the CRP gene are associated with serum C-reactive protein levels and body mass index in healthy individuals in Mexico.	2012	1
J Sunyer	Systemic inflammation, genetic susceptibility and lung function	2008	1
Ming-Sheng Teng	Association between C-reactive protein gene haplotypes and C-reactive protein levels in Taiwanese: interaction with obesity.	2009	1	10.1016/j.atherosclerosis.2008.10.034
Lucia A. Hindorff	Common variants in the CRP gene in relation to longevity and cause-specific mortality in older adults: The Cardiovascular Health Study	2008	5	10.1016/j.atherosclerosis.2007.08.012
Eva Morales	Maternal C-reactive protein levels in pregnancy are associated with wheezing and lower respiratory tract infections in the offspring	2011	1	10.1016/j.ajog.2010.08.056
Akihiko Morita	Association study between C-reactive protein genes and ischemic stroke in Japanese subjects.	2006	1	10.1016/j.amjhyper.2005.11.015
Shaoyong Su	Pleiotropy of C-reactive protein gene polymorphisms with C-reactive protein levels and heart rate variability in healthy male twins.	2009	0	-
Indrani Halder	Polymorphisms in the CRP gene moderate an association between depressive symptoms and circulating levels of C-reactive protein.	2010	13	10.1016/j.bbi.2009.09.014

Evidence compiled by the Personal Genome Project

There are no results from the Personal Genome Project yet. Please come back later.

Publications listed by Genome.gov

There are no results from genome.gov yet. Please come back later.

Users who share this SNP:

John Lloyd Scharf

http://www.snpedia.com/index.php/Rs1205

08.12.2011 21:13

This SNP has an entry on SNPedia:
http://www.snpedia.com/index.php/Rs1205

Bastian Greshake Tzovaras

Thanks

10.12.2011 12:16

Thanks for the pointer. I'll have a look why it does not show it here. :)

SNP rs1205

Basic Information

Genotype Frequency

Allele Frequency

Additional Information