openSNP | rs1143627

Links to SNPedia

Title	Summary
rs1143627 C/C	Common in clinvar

Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).

Publications on this SNP on the Public Library of Science:

First Author	Title	Year of Publication	# of readers
Ying Zhang	IL1 Receptor Antagonist Gene IL1-RN Variable Number of Tandem Repeats Polymorphism and Cancer Risk: A Literature Review and Meta-Analysis	2012	3755
Michelle A. T. Hildebrandt	Genetic Variants in Inflammation-Related Genes Are Associated with Radiation-Induced Toxicity Following Treatment for Non-Small Cell Lung Cancer	2010	6708
Aurora Moen	Role of IL1A rs1800587, IL1B rs1143627 and IL1RN rs2234677 Genotype Regarding Development of Chronic Lumbar Radicular Pain; a Prospective One-Year Study	2014	1879
Xiaoyan Liu	Association Study of Candidate Gene Polymorphisms with Amnestic Mild Cognitive Impairment in a Chinese Population	2012	2464
Steffen Bank	Polymorphisms in the Inflammatory Pathway Genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG Are Associated with Susceptibility of Inflammatory Bowel Disease in a Danish Cohort	2014	5137
David Melzer	A Genome-Wide Association Study Identifies Protein Quantitative Trait Loci (pQTLs)	2008	19813
Jaesung Choi	The Associations between Immunity-Related Genes and Breast Cancer Prognosis in Korean Women	2014	2957
Guoliang Zhang	Allele-Specific Induction of IL-1β Expression by C/EBPβ and PU.1 Contributes to Increased Tuberculosis Susceptibility	2014	6005
Hai-Xiang Su	Mutations of C-Reactive Protein (CRP) -286 SNP, APC and p53 in Colorectal Cancer: Implication for a CRP-Wnt Crosstalk	2014	4528
Jakob Gerhard Stegger	Single Nucleotide Polymorphisms in IL1B and the Risk of Acute Coronary Syndrome: A Danish Case-Cohort Study	2012	2933
Christine Miaskowski	Evidence of Associations between Cytokine Genes and Subjective Reports of Sleep Disturbance in Oncology Patients and Their Family Caregivers	2012	3949
Xuefeng Wang	Interleukin-1β-31C/T and -511T/C Polymorphisms Were Associated with Preeclampsia in Chinese Han Population	2014	2047
Laura Ibáñez	HIV-Infection, Atherosclerosis and the Inflammatory Pathway: Candidate Gene Study in a Spanish HIV-Infected Population	2014	1872
Susanna Esposito	Genetic Polymorphisms and Sepsis in Premature Neonates	2014	5500
Jacob Sode	Anti-TNF Treatment Response in Rheumatoid Arthritis Patients Is Associated with Genetic Variation in the NLRP3-Inflammasome	2014	4635
Vibeke Andersen	Interactions between Diet, Lifestyle and IL10, IL1B, and PTGS2/COX-2 Gene Polymorphisms in Relation to Risk of Colorectal Cancer in a Prospective Danish Case-Cohort Study	2013	2805
Esther Erdei	Cytokines and Tumor Metastasis Gene Variants in Oral Cancer and Precancer in Puerto Rico	2013	2522
Zhihong Gong	Innate Immunity Pathways and Breast Cancer Risk in African American and European-American Women in the Women’s Circle of Health Study (WCHS)	2013	2609
Jiali Xu	Systematic Review and Meta-Analysis on the Association between IL-1B Polymorphisms and Cancer Risk	2013	4815
Ramesh C. Juyal	Potential of Ayurgenomics Approach in Complex Trait Research: Leads from a Pilot Study on Rheumatoid Arthritis	2012	6472
Kaspar René Nielsen	Inherited Inflammatory Response Genes Are Associated with B-Cell Non-Hodgkin’s Lymphoma Risk and Survival	2015	1434
Shaofan Weng	Effects of the Interactions between Dust Exposure and Genetic Polymorphisms in Nalp3, Caspase-1, and IL-1β on the Risk of Silicosis: A Case-Control Study	2015	1530
Daniel T. Barratt	Innate Immune Signalling Genetics of Pain, Cognitive Dysfunction and Sickness Symptoms in Cancer Pain Patients Treated with Transdermal Fentanyl	2015	2411
Martha L. Slattery	The Influence of the CHIEF Pathway on Colorectal Cancer-Specific Mortality	2014	3134
Dorota M. Nowak	Nonrandom Distribution of miRNAs Genes and Single Nucleotide Variants in Keratoconus Loci	2015	1451
You Yin	Interleukin-1β Promoter Polymorphism Enhances the Risk of Sleep Disturbance in Alzheimer’s Disease	2016	1981
Himanshu Rai	Interleukin-1 Gene Cluster Polymorphisms and Their Association with Coronary Artery Disease: Separate Evidences from the Largest Case-Control Study amongst North Indians and an Updated Meta-Analysis	2016	1584
Baltazar González-Andrade	The carriage of interleukin-1B-31C allele plus Staphylococcus aureus* and Haemophilus influenzae increases the risk of recurrent tonsillitis in a Mexican population	2017	1075
Wen-Chien Fan	TLR4/CD14 Variants-Related Serologic and Immunologic Dys-Regulations Predict Severe Sepsis in Febrile De-Compensated Cirrhotic Patients	2016	1173

Publications on this SNP on Mendeley

First Author	Title	Pub. Year	# of Readers	DOI
Daniele Campa	Association of common polymorphisms in inflammatory genes with risk of developing cancers of the upper aerodigestive tract.	2007	4	-
Yingxia Liu	Genetic variants in IL1A and IL1B contribute to the susceptibility to 2009 pandemic H1N1 influenza A virus.	2013	1	10.1186/1471-2172-14-37
L Zhuang	Association of the interleukin 1 beta gene and brain spontaneous activity in amnestic mild cognitive impairment	2012	1
Virginia L Misener	Tagging SNP association study of the IL-1beta gene (IL1B) and childhood-onset mood disorders.	2009	5	10.1002/ajmg.b.30885
Areerat Sa-Ngasang	Association of IL1B -31C/T and IL1RA variable number of an 86-bp tandem repeat with Dengue Shock Syndrome in Thailand.	2014	1	10.1093/infdis/jiu042
Liying Zhuang	Association of the interleukin 1 beta gene and brain spontaneous activity in amnestic mild cognitive impairment.	2012	4	10.1186/1742-2094-9-263
Yingxia Liu	Genetic variants in IL1A and IL1B contribute to the susceptibility to 2009 pandemic H1N1 influenza A virus.	2013	6	10.1186/1471-2172-14-37
Liying Zhuang	Association of the interleukin 1 beta gene and brain spontaneous activity in amnestic mild cognitive impairment.	2012	2	10.1186/1742-2094-9-263
F Hayashi	Association of the -31C/T functional polymorphism in the interleukin-1beta gene with the intractability of Graves' disease and the proportion of T helper type 17 cells.	2009	1	10.1111/j.1365-2249.2009.04034.x
G Moxley	Interleukin-1 region meta-analysis with osteoarthritis phenotypes	2010	3	-
F Hayashi	Association of the -31C/T functional polymorphism in the interleukin-1beta gene with the intractability of Graves' disease and the proportion of T helper type 17 cells.	2009	2	10.1111/j.1365-2249.2009.04034.x
Liying Zhuang	Association of the interleukin 1 beta gene and brain spontaneous activity in amnestic mild cognitive impairment	2012	1	http://dx.doi.org/10.1186/1742-2094-9-263
Liying Zhuang	Association of the interleukin 1 beta gene and brain spontaneous activity in amnestic mild cognitive impairment.	2012	2	10.1186/1742-2094-9-263
L Zhuang	Association of the interleukin 1 beta gene and brain spontaneous activity in amnestic mild cognitive impairment	2012	1	-
Dinorah N Martínez-Carrillo	Association of IL1B -511C/-31T haplotype and Helicobacter pylori vacA genotypes with gastric ulcer and chronic gastritis	2010	5	10.1186/1471-230X-10-126
Virginia L Misener	Tagging SNP association study of the IL-1beta gene (IL1B) and childhood-onset mood disorders.	2009	4	-

Evidence compiled by the Personal Genome Project

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Publications listed by Genome.gov

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Name	rs1143627
Chromosome	2
Position	112836810
Weight of evidence	79

	AG
	AA
	GG
	CT
	TT

SNP rs1143627

Basic Information

Genotype Frequency

Allele Frequency

Additional Information

Links to SNPedia

Publications on this SNP on the Public Library of Science:

Publications on this SNP on Mendeley

Evidence compiled by the Personal Genome Project

Publications listed by Genome.gov

Users who share this SNP:

Genome Browser

Contacts

SNP rs1143627

Basic Information

Genotype Frequency

Allele Frequency

Additional Information

Links to SNPedia

Publications on this SNP on the Public Library of Science:

Publications on this SNP on Mendeley

Evidence compiled by the Personal Genome Project

Publications listed by Genome.gov

Users who share this SNP:

Genome Browser

Human GrCh38/hg38

Contacts