openSNP | rs11209026

Links to SNPedia

Title	Summary
rs11209026 A/A	0.26x lower risk for certain autoimmune diseases.
rs11209026 A/G	0.26x lower risk for certain autoimmune diseases.
rs11209026 G/G	Normal, but higher risk for certain autoimmune diseases.

Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).

Publications on this SNP on the Public Library of Science:

First Author	Title	Year of Publication	# of readers
Isabelle Cleynen	Molecular Reclassification of Crohn's Disease by Cluster Analysis of Genetic Variants	2010	4895
Ying Liu	A Genome-Wide Association Study of Psoriasis and Psoriatic Arthritis Identifies New Disease Loci	2008	29965
Veroushka Ballester	Association of NOD2 and IL23R with Inflammatory Bowel Disease in Puerto Rico	2014	2162
Matthew J. Loza	Assembly of Inflammation-Related Genes for Pathway-Focused Genetic Analysis	2007	18410
Patrick Danoy	Association of Variants at 1q32 and STAT3 with Ankylosing Spondylitis Suggests Genetic Overlap with Crohn's Disease	2010	8665
Andre Franke	Systematic Association Mapping Identifies NELL1 as a Novel IBD Disease Gene	2007	10384
Jürgen Glas	rs1004819 Is the Main Disease-Associated IL23R Variant in German Crohn's Disease Patients: Combined Analysis of IL23R, CARD15, and OCTN1/2 Variants	2007	7480
Ya-Feng Wen	rs10865331 Associated with Susceptibility and Disease Severity of Ankylosing Spondylitis in a Taiwanese Population	2014	2060
Joyce Y. Tung	Efficient Replication of over 180 Genetic Associations with Self-Reported Medical Data	2011	11673
Jürgen Glas	PTPN2 Gene Variants Are Associated with Susceptibility to Both Crohn's Disease and Ulcerative Colitis Supporting a Common Genetic Disease Background	2012	5100
Debby Laukens	Evidence for Significant Overlap between Common Risk Variants for Crohn's Disease and Ankylosing Spondylitis	2010	4139
Pengli Yu	Association of Single Nucleotide Polymorphisms of IL23R and IL17 with Ulcerative Colitis Risk in a Chinese Han Population	2012	3389
Steffen Bank	Polymorphisms in the Inflammatory Pathway Genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG Are Associated with Susceptibility of Inflammatory Bowel Disease in a Danish Cohort	2014	5137
Garima Juyal	An Investigation of Genome-Wide Studies Reported Susceptibility Loci for Ulcerative Colitis Shows Limited Replication in North Indians	2011	4399
Jürgen Glas	The Role of Osteopontin (OPN/SPP1) Haplotypes in the Susceptibility to Crohn's Disease	2011	4773
Karin Fransen	Limited Evidence for Parent-of-Origin Effects in Inflammatory Bowel Disease Associated Loci	2012	2553
Josef Wagner	Interaction of Crohn's Disease Susceptibility Genes in an Australian Paediatric Cohort	2010	3121
Jürgen Glas	PTGER4 Expression-Modulating Polymorphisms in the 5p13.1 Region Predispose to Crohn's Disease and Affect NF-κB and XBP1 Binding Sites	2012	2895
Jürgen Glas	Evidence for STAT4 as a Common Autoimmune Gene: rs7574865 Is Associated with Colonic Crohn's Disease and Early Disease Onset	2010	4632
Jürgen Glas	CEACAM6 Gene Variants in Inflammatory Bowel Disease	2011	3425
James Cheng-Chung Wei	Association Study of Polymorphisms rs4552569 and rs17095830 and the Risk of Ankylosing Spondylitis in a Taiwanese Population	2013	3139
Jürgen Glas	Analysis of IL12B Gene Variants in Inflammatory Bowel Disease	2012	5074
Cécile Libioulle	Novel Crohn Disease Locus Identified by Genome-Wide Association Maps to a Gene Desert on 5p13.1 and Modulates Expression of PTGER4	2007	18177
Irina Dinu	SNP-SNP Interactions Discovered by Logic Regression Explain Crohn's Disease Genetics	2012	7847
Camille Jung	Genotype/Phenotype Analyses for 53 Crohn’s Disease Associated Genetic Polymorphisms	2012	4139
Svetlana Pidasheva	Functional Studies on the IBD Susceptibility Gene IL23R Implicate Reduced Receptor Function in the Protective Genetic Variant R381Q	2011	7062
Cinzia Ciccacci	A Multilocus Genetic Study in a Cohort of Italian SLE Patients Confirms the Association with STAT4 Gene and Describes a New Association with HCP5 Gene	2014	2294
Haoyan Chen	A Genetic Risk Score Combining Ten Psoriasis Risk Loci Improves Disease Prediction	2011	8210
Julia Diegelmann	Intestinal DMBT1 Expression Is Modulated by Crohn’s Disease-Associated IL23R Variants and by a DMBT1 Variant Which Influences Binding of the Transcription Factors CREB1 and ATF-2	2013	3318
Jürgen Glas	IRGM Variants and Susceptibility to Inflammatory Bowel Disease in the German Population	2013	4346
Luz María Medrano	Th17-Related Genes and Celiac Disease Susceptibility	2012	4354
Eimear E. Kenny	A Genome-Wide Scan of Ashkenazi Jewish Crohn's Disease Suggests Novel Susceptibility Loci	2012	26482
María Carmen Cénit	No Evidence of Association between Common Autoimmunity STAT4 and IL23R Risk Polymorphisms and Non-Anterior Uveitis	2013	1451
Vincent Botta	Exploiting SNP Correlations within Random Forest for Genome-Wide Association Studies	2014	10920
Kei Onodera	Low-Frequency IL23R Coding Variant Associated with Crohn’s Disease Susceptibility in Japanese Subjects Identified by Personal Genomics Analysis	2015	1587
Zhengxuan Jiang	Interleukin-23 Receptor Gene Polymorphism May Enhance Expression of the IL-23 Receptor, IL-17, TNF-α and IL-6 in Behcet’s Disease	2015	2075
Orazio Palmieri	Crohn’s Disease Localization Displays Different Predisposing Genetic Variants	2017	1725
Marijn C. Visschedijk	Pooled Resequencing of 122 Ulcerative Colitis Genes in a Large Dutch Cohort Suggests Population-Specific Associations of Rare Variants in MUC2	2016	1421
Nikolai Dyrberg Loft	Genetic polymorphisms associated with psoriasis and development of psoriatic arthritis in patients with psoriasis	2018	890
Margaret G. Ehm	Phenome-wide association study using research participants’ self-reported data provides insight into the Th17 and IL-17 pathway	2017	3720
Bartłomiej Kisiel	The association between 38 previously reported polymorphisms and psoriasis in a Polish population: High predicative accuracy of a genetic risk score combining 16 loci	2017	1379

Publications on this SNP on Mendeley

First Author	Title	Pub. Year	# of Readers	DOI
Robert N Baldassano	Association of variants of the interleukin-23 receptor gene with susceptibility to pediatric Crohn's disease.	2007	2	-
R Duerr	A genome-wide association study identifies IL23R as an inflammatory bowel disease gene	2006	1
Rajan P Nair	Genetic evidence for involvement of the IL23 pathway in Thai psoriatics.	2010	3	10.1007/s00403-009-0986-y
Maria Gazouli	NOD2/CARD15, ATG16L1 and IL23R gene polymorphisms and childhood-onset of Crohn's disease.	2010	19	10.3748/wjg.v16.i14.1753
Richard H Duerr	Bowel Disease Gene	2006	14	10.1126/science.1135245
John D Reveille	Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci	2010	1	-
Tomoiku Takaku	Interleukin-23 receptor (IL-23R) gene polymorphisms in acquired aplastic anemia.	2009	3	10.1007/s00277-008-0666-6
F. L. van de Veerdonk	Role of Interleukin-23 (IL-23) Receptor Signaling for IL-17 Responses in Human Lyme Disease	2011	6	10.1128/IAI.05242-11
C Büning	Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis.	2007	5	APT3446 [pii]\r10.1111/j.1365-2036.2007.03446.x
Zhenhua Duan	Interleukin-23 receptor genetic polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis.	2012	0	10.1007/s00296-010-1769-7
C Nunez	IL23R: a susceptibility locus for celiac disease and multiple sclerosis?	2008	1	gene200816 [pii]\n10.1038/gene.2008.16
Richard H Duerr	A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.	2006	130	-
Mark S Silverberg	Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study.	2009	63	10.1038/ng0609-762a
John Reveille	Reveille AS GWAS - Suppl Info	2010	1	10.1038/ng.513
Richard H. Duerr	A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene	2006	32	10.1126/science.1135245
Amir Kadi	The IL23R non-synonymous polymorphism rs11209026 is associated with radiographic sacroiliitis in spondyloarthritis.	2013	2	10.1002/art.38060
Cornelia Tillack	Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment.	2014	9	10.1136/gutjnl-2012-302853
Proton Rahman	Association of interleukin-23 receptor variants with ankylosing spondylitis.	2008	6	10.1002/art.23389
J R Fraser Cummings	Contribution of the novel inflammatory bowel disease gene IL23R to disease susceptibility and phenotype.	2007	9	10.1002/ibd.20180
R H Duerr	A genome-wide association study identifies IL23R as an inflammatory bowel disease gene	2006	4	1135245 [pii]\n10.1126/science.1135245
Devendra K Amre	Association between genetic variants in the IL-23R gene and early-onset Crohn's disease: results from a case-control and family-based study among Canadian children.	2008	0
J E Hollis-Moffatt	Evidence for association of an interleukin 23 receptor variant independent of the R381Q variant with rheumatoid arthritis.	2009	6	-
P L Lakatos	ATG16L1 and IL23 receptor (IL23R) genes are associated with disease susceptibility in Hungarian CD patients.	2008	7	10.1016/j.dld.2008.03.022
C Büning	Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis.	2007	3	-
Rajan P Nair	Polymorphisms of the IL12B and IL23R genes are associated with psoriasis.	2008	19	10.1038/sj.jid.5701255
Adriana Machado Saraiva	Evaluation of IL17A expression and of IL17A, IL17F and IL23R gene polymorphisms in Brazilian individuals with periodontitis	2013	8	10.1016/j.humimm.2012.10.026
Amir Kadi	The IL23R non-synonymous polymorphism rs11209026 is associated with radiographic sacroiliitis in spondyloarthritis	2013	0	10.1002/art.38060
A Carvalho	Prognostic significance of genetic variants in the IL-23/Th17 pathway for the outcome of T cell-depleted allogeneic stem cell transplantation.	2010	3	10.1038/bmt.2010.28
A Fischer	Association of inflammatory bowel disease risk loci with sarcoidosis, and its acute and chronic subphenotypes.	2011	10	10.1183/09031936.00049410
Robert N Baldassano	Association of variants of the interleukin-23 receptor gene with susceptibility to pediatric Crohn's disease.	2007	6	-
Lynnette R Ferguson	IL23R and IL12B SNPs and Haplotypes Strongly Associate with Crohn's Disease Risk in a New Zealand Population.	2010	5	10.1155/2010/539461
Amanda K Huber	Interleukin (IL)-23 receptor is a major susceptibility gene for Graves' ophthalmopathy: the IL-23/T-helper 17 axis extends to thyroid autoimmunity.	2008	4	10.1210/jc.2007-2190
Svetlana Pidasheva	Functional studies on the IBD susceptibility gene IL23R implicate reduced receptor function in the protective genetic variant R381Q.	2011	5	10.1371/journal.pone.0025038
Andreea Nicoleta Boca	Genetic variations in IL6 and IL12B decreasing the risk for psoriasis	2013	4	10.1016/j.imlet.2013.09.028
Y Liu	A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci	2008	1
Javier Oliver	Replication of an Association Between IL23R Gene Polymorphism With Inflammatory Bowel Disease	2007	4	10.1016/j.cgh.2007.05.002
Yun Li	1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data	2012	31	10.1038/ejhg.2012.3
Massimo Mangino	Association analysis of IL-12B and IL-23R polymorphisms in myocardial infarction.	2008	2	10.1007/s00109-007-0264-4
Richard H Duerr	A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.	2006	1	10.1126/science.1135245
Jie Huang	1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data.	2012	27	10.1038/ejhg.2012.3
Camille Jung	Genotype/Phenotype Analyses for 53 Crohn's Disease Associated Genetic Polymorphisms	2012	12	10.1371/journal.pone.0052223
Mattia Lauriola	IL23R, NOD2/CARD15, ATG16L1 and PHOX2B polymorphisms in a group of patients with Crohn's disease and correlation with sub-phenotypes.	2011	3	10.3892/ijmm.2010.591
Camille Jung	Genotype/phenotype analyses for 53 Crohn's disease associated genetic polymorphisms.	2012	5	10.1371/journal.pone.0052223
Hergen Spits	Functional Studies on the IBD Susceptibility Gene IL23R Implicate Reduced Receptor Function in the Protective Genetic Variant R381Q	2011	10	10.1371/journal.pone.0025038
J Van Limbergen	IL23R Arg381Gln is associated with childhood onset inflammatory bowel disease in Scotland.	2007	10	10.1136/gut.2007.122069
E Gallo	The relationship between tnf-α promoter and il12b/il23r gene polymorphisms and the efficacy of anti-tnf-α therapy in psoriasis: a case control study.	2013	1	10.1111/bjd.12425
R H Duerr	A genome-wide association study identifies IL23R as an inflammatory bowel disease gene	2006	28	1135245 [pii]\n10.1126/science.1135245
Young Ho Lee	Associations between interleukin-23R and interleukin-12B polymorphisms and psoriasis susceptibility: a meta-analysis.	2013	1	10.3109/08820139.2013.810241
Tianchen Zhang	Interleukin-23 receptor genetic polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis	2012	2	10.1007/s00296-010-1769-7
Ying Liu	A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.	2008	54	10.1371/journal.pgen.1000041
John D Reveille	Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.	2010	51	10.1038/ng.513
V. S. Costa	Protective effect of interleukin-23A (IL23A) haplotype variants on type 1A diabetes mellitus in a Brazilian population	2013	4	10.1016/j.cyto.2013.03.015
Ziad Kanaan	Perianal Crohn's disease: Predictive factors and genotype-phenotype correlations	2012	1	10.1159/000335745
E Gallo	The relationship between tnf-α promoter and il12b/il23r gene polymorphisms and the efficacy of anti-tnf-α therapy in psoriasis: a case control study.	2013	3	10.1111/bjd.12425
Ana Márquez	IL23R and IL12B polymorphisms in Spanish IBD patients: no evidence of interaction.	2008	5	10.1002/ibd.20463
Deepak Jadon	Exploring ankylosing spondylitis-associated ERAP1, IL23R and IL12B gene polymorphisms in subphenotypes of psoriatic arthritis.	2012	3	10.1093/rheumatology/kes254
Richard H Duerr	A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.	2006	114	10.1126/science.1135245
Ulrike Hüffmeier	Genetic variants of the IL-23R pathway: association with psoriatic arthritis and psoriasis vulgaris, but no specific risk factor for arthritis.	2009	10	10.1038/jid.2008.233
Petra Dusatkova	Association of IL23R p.381Gln and ATG16L1 p.197Ala with Crohn disease in the Czech population.	2009	4	10.1097/MPG.0b013e31819344ee
Svetlana Pidasheva	Functional studies on the IBD susceptibility gene IL23R implicate reduced receptor function in the protective genetic variant R381Q	2011	13	10.1371/journal.pone.0025038
Robert N. Baldassano	{A figure is presented}Association of Variants of the Interleukin-23 Receptor Gene With Susceptibility to Pediatric Crohn's Disease	2007	7	10.1016/j.cgh.2007.04.024
B Rueda	The IL23R Arg381Gln non-synonymous polymorphism confers susceptibility to ankylosing spondylitis.	2008	5	10.1136/ard.2007.080283
Robert N Baldassano	Association of variants of the interleukin-23 receptor gene with susceptibility to pediatric Crohn's disease.	2007	7	10.1016/j.cgh.2007.04.024
J E Hollis-Moffatt	Evidence for association of an interleukin 23 receptor variant independent of the R381Q variant with rheumatoid arthritis.	2009	7	10.1136/ard.2008.090142
John D Reveille	Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci	2010	1	-
Jürgen Glas	rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.	2007	12	10.1371/journal.pone.0000819
E Gallo	The relationship between tumour necrosis factor (TNF)-α promoter and IL12B/IL-23R genes polymorphisms and the efficacy of anti-TNF-α therapy in psoriasis: a case-control study.	2013	1	10.1111/bjd.12425
V S Costa	Protective effect of interleukin-23A (IL23A) haplotype variants on type 1A diabetes mellitus in a Brazilian population.	2013	2	10.1016/j.cyto.2013.03.015
P. L. Lakatos	ATG16L1 and IL23 receptor (IL23R) genes are associated with disease susceptibility in Hungarian CD patients	2008	6	10.1016/j.dld.2008.03.022
Adriana Machado Saraiva	Evaluation of IL17A expression and of IL17A, IL17F and IL23R gene polymorphisms in Brazilian individuals with periodontitis.	2013	2	10.1016/j.humimm.2012.10.026
J Limbergen	IL23R Arg381Gln is associated with childhood onset inflammatory bowel disease in Scotland	2007	8	10.1136/gut.2007.122069
Akira Oka	IL12B and IL23R gene SNPs in Japanese psoriasis.	2013	1	10.1007/s00251-013-0721-x
Anne Hinks	Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP1 with the enthesitis related arthritis subtype and IL23R with juvenile psoriatic arthritis.	2011	11	10.1186/ar3235
R. H. Duerr	A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene	2006	39	10.1126/science.1135245
E Sáfrány	Variants of the IL23R gene are associated with ankylosing spondylitis but not with Sjögren syndrome in Hungarian population samples.	2009	5	10.1111/j.1365-3083.2009.02265.x
Rebecca L Roberts	IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease.	2007	10	10.1111/j.1572-0241.2007.01525.x
RH Duerr	A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.	2006	1	10.1126/science.1135245
B Rueda	The IL23R Arg381Gln non-synonymous polymorphism confers susceptibility to ankylosing spondylitis.	2008	4	-
Deepak Jadon	Exploring ankylosing spondylitis-associated ERAP1, IL23R and IL12B gene polymorphisms in subphenotypes of psoriatic arthritis.	2013	7	10.1093/rheumatology/kes254
T Merriman	IL-23R rs11209026 polymorphism modulates IL-17A expression in patients with rheumatoid arthritis	2012	3	10.1038/gene.2011.80
Ying Liu	A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.	2008	1	10.1371/journal.pgen.1000041
Mark J Duerr, RH, Taylor, KD, Brant, SR, Rioux, JD, Sil berg, MS, Daly	A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.	2006	1	10.1126/science.1135245
Mauricio Venegas	IL-23R Arg381Gln polymorphism in Chilean patients with inflammatory bowel disease.	2008	3	10.1684/ecn.2008.0135
Márcia Luiza Baptista	CARD15 and IL23R influences Crohn's disease susceptibility but not disease phenotype in a Brazilian population.	2008	7	10.1002/ibd.20372
Richard H Duerr	A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.	2006	26	10.1126/science.1135245
Richard H Duerr	A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene	2006	1
Z Lin	Genetic association of nonsynonymous variants of the IL23R with familial and sporadic inflammatory bowel disease in women	2010	5	10.1007/s10620-009-0782-8
Gwan Gyu Song	Associations between interleukin-23 receptor polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis	2012	1	10.1007/s11033-012-1955-7
Stuart I Davidson	Association of ERAP1, but not IL23R, with ankylosing spondylitis in a Han Chinese population.	2009	4	-
Lynnette R. Ferguson	IL23R and IL12B SNPs and haplotypes strongly associate with Crohn's disease risk in a New Zealand population	2010	5	10.1155/2010/539461
J Hazlett	IL-23R rs11209026 polymorphism modulates IL-17A expression in patients with rheumatoid arthritis	2011	3	10.1038/gene.2011.80
Nathalie Vermeulen	IL-23R Arg381Gln polymorphism in Chilean patients with inflammatory bowel disease.	2008	6	-
C Tillack	Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-gamma-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment	2013	1	gutjnl-2012-302853 [pii]\n10.1136/gutjnl-2012-302853
Cornelia Tillack	Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment.	2013	3	10.1136/gutjnl-2012-302853
Sung Jae Choi	Associations between interleukin-23R polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis	2012	8	10.1007/s00011-011-0398-2
V S Costa	Protective effect of interleukin-23A (IL23A) haplotype variants on type 1A diabetes mellitus in a Brazilian population.	2013	2	10.1016/j.cyto.2013.03.015
Zhenwu Lin	Genetic association of nonsynonymous variants of the IL23R with familial and sporadic inflammatory bowel disease in women.	2010	8	10.1007/s10620-009-0782-8
Devendra K Amre	Association between genetic variants in the IL-23R gene and early-onset Crohn's disease: results from a case-control and family-based study among Canadian children.	2008	6	10.1111/j.1572-0241.2007.01661.x
M Lacher	Association of the interleukin-23 receptor gene variant rs11209026 with Crohn's disease in German children.	2010	5	10.1111/j.1651-2227.2009.01680.x
Rinse K Weersma	ATG16L1 and IL23R are associated with inflammatory bowel diseases but not with celiac disease in the Netherlands.	2008	9	10.1111/j.1572-0241.2007.01660.x

Evidence compiled by the Personal Genome Project

There are no results from the Personal Genome Project yet. Please come back later.

Publications listed by Genome.gov

First Author	Title	Journal	Publication Date	Trait	p-value	Confidence Interval
Kugathasan S	Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.	Nat Genet	08/31/2008	Inflammatory bowel disease	7.0e-11	[1.92-3.45]
Huang J	1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data.	Eur J Hum Genet	02/01/2012	Crohn's disease	4.0e-21	[2.91-3.44]
Libioulle C	Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4.	PLoS Genet	03/05/2007	Crohn's disease	2.0e-18	[NR]
Reveille JD	Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.	Nat Genet	01/10/2010	Ankylosing spondylitis	9.0e-14	[1.56-2.27]
Duerr RH	A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.	Science	10/26/2006	Inflammatory bowel disease	4.0e-11	[2.33-6.66]
Kenny EE	A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci.	PLoS Genet	03/08/2012	Crohn's disease	1.0e-18	[2.10-2.35]
Franke A	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Nat Genet	11/21/2010	Crohn's disease	1.0e-64	[2.36-3.00]
Evans DM	Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility.	Nat Genet	07/10/2011	Ankylosing spondylitis	2.0e-17	NR
Barrett JC	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	Nat Genet	11/15/2009	Ulcerative colitis	3.0e-10	NR
Anderson CA	Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.	Nat Genet	02/06/2011	Ulcerative colitis	5.0e-28	[1.57-1.92]

Name	rs11209026
Chromosome	1
Position	67240275
Weight of evidence	239

SNP rs11209026

Basic Information

Genotype Frequency

Allele Frequency

Additional Information

Links to SNPedia

Publications on this SNP on the Public Library of Science:

Publications on this SNP on Mendeley

Evidence compiled by the Personal Genome Project

Publications listed by Genome.gov

Users who share this SNP:

Genome Browser

Contacts