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SNP rs1050450
Basic Information
Name
rs1050450
Chromosome
3
Position
49357401
Weight of evidence
42
Genotype Frequency
AG
GG
--
AA
33%
53%
8%
6%
Allele Frequency
A
T
G
C
-
22%
69%
8%
Additional Information
SNPedia (1)
PLoS (7)
Mendeley (23)
Personal Genome Project (0)
Genome.gov (0)
Other users (1386)
Comments (0)
Links to SNPedia
Title
Summary
rs1050450 C/C
Common in clinvar
Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).
Publications on this SNP on the Public Library of Science:
First Author
Title
Year of Publication
# of readers
Katrzyna Jaworska
A Low Selenium Level Is Associated with Lung and Laryngeal Cancers
2013
3553
Catherine Méplan
Polymorphisms in Thioredoxin Reductase and Selenoprotein K Genes and Selenium Status Modulate Risk of Prostate Cancer
2012
3451
Jeffrey J. W. Verschuren
Systematic Testing of Literature Reported Genetic Variation Associated with Coronary Restenosis: Results of the GENDER Study
2012
2110
Catherine Méplan
Association between Polymorphisms in Glutathione Peroxidase and Selenoprotein P Genes, Glutathione Peroxidase Activity, HRT Use and Breast Cancer Risk
2013
4459
Andrew J. Pellatt
SEPP1
Influences Breast Cancer Risk among Women with Greater Native American Ancestry: The Breast Cancer Health Disparities Study
2013
2079
Lulin Huang
Association Study of Polymorphisms in Selenoprotein Genes and Kashin–Beck Disease and Serum Selenium/Iodine Concentration in a Tibetan Population
2013
3792
Albina N. Minlikeeva
Single-Nucleotide Polymorphisms and Markers of Oxidative Stress in Healthy Women
2016
1476
Publications on this SNP on Mendeley
First Author
Title
Pub. Year
# of Readers
DOI
P Bhatti
Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors
2009
2
18/6/1841 [pii]\r10.1158/1055-9965.EPI-09-0197
Jiawei Chen
GPx-1 polymorphism (rs1050450) contributes to tumor susceptibility: evidence from meta-analysis.
2011
1
-
H.A. Ireland
Association between the rs1050450 glutathione peroxidase-1 (C > T) gene variant and peripheral neuropathy in two independent samples of subjects with diabetes mellitus
2012
13
10.1016/j.numecd.2010.08.001
Zhiqiang Hong
GPX1 gene Pro200Leu polymorphism, erythrocyte GPX activity, and cancer risk
2012
2
10.1007/s11033-012-2234-3
Tine Halsen Malling
Genetic polymorphisms in antioxidative enzymes are associated to forced expiratory volume in 1 s (FEV(1) ) in smokers independently of asthma.
2011
2
10.1111/j.1752-699X.2011.00245.x
Ole Raaschou-Nielsen
GPX1 Pro198Leu polymorphism, interactions with smoking and alcohol consumption, and risk for lung cancer
2007
1
10.1016/j.canlet.2006.05.006
David G Cox
Gene x Gene interaction between MnSOD and GPX-1 and breast cancer risk: a nested case-control study.
2006
9
10.1186/1471-2407-6-217
Nishi Karunasinghe
Prostate disease risk factors among a New Zealand cohort.
2012
1
10.1159/000346279
Jiawei Chen
GPx-1 polymorphism (rs1050450) contributes to tumor susceptibility: evidence from meta-analysis.
2011
1
10.1007/s00432-011-1033-x
T S Tang
发挥图书馆在促进高校青年教师阅读中的作用
2010
0
10.1016/j.numecd.2010.08.001
Ole Raaschou-Nielsen
GPX1 Pro198Leu polymorphism, interactions with smoking and alcohol consumption, and risk for lung cancer.
2007
1
10.1016/j.canlet.2006.05.006
Parveen Bhatti
Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors.
2009
1
-
P Bhatti
Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors
2009
1
Parveen Bhatti
Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors.
2009
1
-
T. S. Tang
Association between the rs1050450 glutathione peroxidase-1 (C > T) gene variant and peripheral neuropathy in two independent samples of subjects with diabetes mellitus
2012
14
10.1016/j.numecd.2010.08.001
Parveen Bhatti
Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors.
2009
6
10.1158/1055-9965.EPI-09-0197
T S Tang
Association between the rs1050450 glutathione peroxidase-1 (C > T) gene variant and peripheral neuropathy in two independent samples of subjects with diabetes mellitus.
2010
8
10.1016/j.numecd.2010.08.001
P Bhatti
Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors
2009
1
Ting-Yuan David Cheng
Genetic Variation in Myeloperoxidase Modifies the Association of Serum alpha-Tocopherol with Aggressive Prostate Cancer among Current Smokers.
2011
6
-
Maria A Solodilova
The C718T polymorphism in the 3′-untranslated region of glutathione peroxidase-4 gene is a predictor of cerebral stroke in patients with essential hypertension
2012
2
10.1038/hr.2011.213
Ole Raaschou-Nielsen
GPX1 Pro198Leu polymorphism, interactions with smoking and alcohol consumption, and risk for lung cancer.
2007
2
-
J C Charniot
Manganese superoxide dismutase dimorphism relationship with severity and prognosis in cardiogenic shock due to dilated cardiomyopathy.
2011
0
-
David G Cox
Gene × Gene interaction between MnSOD and GPX-1 and breast cancer risk: a nested case-control study
2006
8
10.1186/1471-2407-6-217
Evidence compiled by the
Personal Genome Project
There are no results from the
Personal Genome Project
yet. Please come back later.
Publications listed by
Genome.gov
There are no results from
genome.gov
yet. Please come back later.
Users who share this SNP:
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Human GrCh38/hg38
Genome
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Gene structures from GENCODE 21
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