"Association of KIBRA rs17070145 polymorphism and episodic memory in individuals with severe TBI
Results: T-allele non-carriers performed better than carriers on multiple episodic memory measures. At 6 months, T-allele non-carriers performed better for delayed recall measures on the SRT. At 12 months, T-allele non-carriers performed better on multiple SRT measures and on List-B learning with CVLT-II. No associations occurred with executive function or global outcome measures.
Conclusion: These results suggest that rs17070145 T-allele effects are specific to episodic memory and support the hypothesis that associations between rs17070145 variation and memory are disparate between healthy and impaired populations. "
https://pubmed.ncbi.nlm.nih.gov/22794909/
"We report a significant association of rs17070145 with both episodic (r = 0.068, P = 0.001) and working memory (r = 0.035, P = 0.018). In summary, our findings indicate that SNP rs17070145 located within KIBRA explains 0.5% of the variance for episodic memory tasks and 0.1% of the variance for working memory tasks in samples of primarily Caucasian background."
https://onlinelibrary.wiley.com/doi/abs/10.1002/ajmg.b.32101
"Moreover, among older adults T-allele carriers of the examined KIBRA polymorphism showed better spatial learning compared to C homozygotes. Together these findings provide the first evidence for an effect of the KIBRA rs17070145 polymorphism on spatial memory in humans and age differences in the reliance on landmark and boundary-related spatial information."
https://onlinelibrary.wiley.com/doi/abs/10.1002/hipo.22148
Please select an SNP from the list below:
rs17070145
Use the SNP(Amino Acid; Amino Acid) format.
