Treatment with progesterone in mid 20s (for possible miscarriage) resulted in period of hypothyroidism, treated with Thyroxin 12months, thyroid function restored. But thyroid function is disturbed (moves towards hypothyroidism) with consumption of too much soy - ie, soy sauce, tofu, soya beans. Sister's thyroid failed in mid-60s (on daily Oroxine). Male cousin, maternal side, has had 3 events of hyperthyroidism.