openSNP

Phenotype: Type 2 Diabetes +rs13266634

rs13266634 is a SNP in the zinc transporter protein member 8 SLC30A8 gene that has primarily been associated with type-2 diabetes in several studies.

This SNP is also known as the Arg325Trp or R325W variant; the (C) allele encodes the arginine (R), and the (T) allele encodes the Tryptophan (W).

The major alleles of the SLC30A8 SNP rs13266634 and the HHEX SNP rs7923837 associate with reduced insulin secretion, but not with insulin resistance.

46% of European non-diabetic offspring of type-2 diabetes patients are rs13266634(C;C) homozygotes; they are diabetes-prone and characterised by a 19% decrease in first-phase insulin release following an intravenous glucose load.

Magnitude: 2.5
Frequency: 38.9%

Phenotype	Number of Users
Urticaria	34
Significantly increased Risk of Heart Disease	25
Crohn's Disease +rs2241880	29
Throat, Stomach Cancer +rs2274223	26
Exercise Induced Ischemia +rs1024611	16
rs429358	19

User	Variation
BD	Rs1326634cc
Tahiram	Rs1326634cc
Katie	Not diagnosed yet but have rs13266634(c;t).
kell	Not diagnosed yet but have rs13266634(C;T).
atelepen	Rs1326634cc
Benjamin Willis	Not diagnosed yet but have rs13266634(c;t).
Anaro Lexnon	No
B	Not diagnosed yet but have rs13266634(c;t).
Kellie Wilton	Rs1326634cc
Dan	No
Nate S	No
lms18808	Rs1326634cc
Gollaher@gmail.com	No
k9hooker	No
ladynajera	No
Carole Hogan	No
fairyeyes04	No
Whynot	No
jwater148	No
An	Not diagnosed yet but have rs13266634(c;t).
Bec1980	No
Chris1507	Rs1326634cc
Aternias	Rs1326634cc
Franzi	No
SolLee	Rs1326634cc
jellicoe1992	Not diagnosed yet but have rs13266634(c;t).
Kaley White	This is a genotype, not a phenotype
otis	No
PQ_NeroDiv	Not diagnosed yet but have rs13266634(c;t).

Known Phenotypes:

Rs1326634cc
Not diagnosed yet but have rs13266634(c;t).
No
This is a genotype, not a phenotype

Phenotype: Type 2 Diabetes +rs13266634

Known Phenotypes:

Contacts