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SNP rs8192678
Basic Information
Name
rs8192678
Chromosome
4
Position
23814039
Weight of evidence
55
Genotype Frequency
Allele Frequency
Additional Information
SNPedia (4)
PLoS (4)
Mendeley (27)
Personal Genome Project (0)
Genome.gov (0)
Other users (1714)
Comments (0)
Links to SNPedia
Title
Summary
rs8192678 A/A
Higher blood pressure if <50
rs8192678 A/G
Higher blood pressure if <50
rs8192678 C/C
No summary provided.
rs8192678 G/G
Normal
Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).
Publications on this SNP on the Public Library of Science:
First Author
Title
Year of Publication
# of readers
Ekta Rai
The Interactive Effect of
SIRT1
Promoter Region Polymorphism on Type 2 Diabetes Susceptibility in the North Indian Population
2012
4570
John Paul SanGiovanni
DNA Sequence Variants in
PPARGC1A
, a Gene Encoding a Coactivator of the ω-3 LCPUFA Sensing PPAR-RXR Transcription Complex, Are Associated with NV AMD and AMD-Associated Loci in Genes of Complement and VEGF Signaling Pathways
2013
4090
Peter Steinbacher
The Single Nucleotide Polymorphism Gly482Ser in the PGC-1α Gene Impairs Exercise-Induced Slow-Twitch Muscle Fibre Transformation in Humans
2015
3494
Rebecca Grealy
Evaluation of a 7-Gene Genetic Profile for Athletic Endurance Phenotype in Ironman Championship Triathletes
2015
4679
Publications on this SNP on Mendeley
First Author
Title
Pub. Year
# of Readers
DOI
Yan Su
Association study between PPARGC1A Thr394Thr/ Gly482Ser polymorphisms and type 2 diabetes
2008
0
Karani Santhanakrishnan Vimaleswaran
The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals.
2008
7
10.1152/japplphysiol.90423.2008
Karani Santhanakrishnan Vimaleswaran
The Gly482Ser genotype at the PPARGC1A gene and elevated blood pressure: a meta-analysis involving 13,949 individuals
2008
0
10.1152/japplphysiol.90423.2008
Tatsuo Inamine
Association of genes involved in bile acid synthesis with the progression of primary biliary cirrhosis in Japanese patients.
2013
3
10.1007/s00535-012-0730-9
P W Franks
PPARGC1A coding variation may initiate impaired NEFA clearance during glucose challenge.
2007
6
10.1007/s00125-006-0580-1
Shuxia Wang
Polymorphisms of the peroxisome proliferator-activated receptor-gamma coactivator-1alpha gene are associated with hypertrophic cardiomyopathy and not with hypertension hypertrophy.
2007
3
10.1515/CCLM.2007.189
E C Brito
PPARGC1A sequence variation and cardiovascular risk-factor levels: a study of the main genetic effects and gene x environment interactions in children from the European Youth Heart Study.
2009
0
P W Franks
Common variation in PPARGC1A/B and progression to diabetes or change in metabolic traits following preventive interventions: the Diabetes Prevention Program.
2013
0
10.1007/s00125-013-2911-3
Joanne Clark
Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease.
2011
10
10.1186/1471-2350-12-69
A Maver
Peroxisome proliferator-activated receptor gamma/Pro12Ala polymorphism and peroxisome proliferator-activated receptor gamma coactivator-1 alpha/Gly482Ser polymorphism in patients with sarcoidosis.
2008
2
K Mirzaei
An Exonic Peroxisome Proliferator-Activated Receptor- (gamma) Coactivator-1 (alpha) Variation May Mediate the Resting Energy Expenditure through a Potential Regulatory Role on Important Gene Expression in This Pathway
2012
1
-
P W Franks
Common variation in PPARGC1A/B and progression to diabetes or change in metabolic traits following preventive interventions: the Diabetes Prevention Program24
2013
0
N Eynon
Do PPARGC1A and PPARalpha polymorphisms influence sprint or endurance phenotypes?
2010
9
10.1111/j.1600-0838.2009.00930.x
Tatsuo Inamine
Association of genes involved in bile acid synthesis with the progression of primary biliary cirrhosis in Japanese patients.
2013
0
10.1007/s00535-012-0730-9
P W Franks
PPARGC1A coding variation may initiate impaired NEFA clearance during glucose challenge.
2007
0
Yan Su
Association study between PPARGC1A Thr394Thr/ Gly482Ser polymorphisms and type 2 diabetes
2008
0
Gertrud Kacerovsky-Bielesz
Short-Term Exercise Training Does Not Stimulate Skeletal Muscle ATP Synthesis in Relatives of Humans With Type 2 Diabetes
2009
0
Gertrud Kacerovsky-Bielesz
Short-term exercise training does not stimulate skeletal muscle ATP synthesis in relatives of humans with type 2 diabetes.
2009
8
10.2337/db08-1240
Gertrud Kacerovsky-Bielesz
Short-Term Exercise Training Does Not Stimulate Skeletal Muscle ATP Synthesis in Relatives of Humans With Type 2 Diabetes
2009
0
10.2337/db08-1240
Shuxia Wang
Polymorphisms of the peroxisome proliferator-activated receptor-gamma coactivator-1alpha gene are associated with hypertrophic cardiomyopathy and not with hypertension hypertrophy.
2007
0
Chang-Duk Ha
Relationship of PGC-1α Gene Polymorphism With Insulin Resistance Syndrome in Korean Children.
2013
1
10.1177/1010539513477685
Joanne Clark
Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease.
2011
10
10.1186/1471-2350-12-69
N Eynon
Do PPARGC1A and PPARalpha polymorphisms influence sprint or endurance phenotypes?
2010
0
C M Povel
Glucose levels and genetic variants across transcriptional pathways: interaction effects with BMI.
2010
6
10.1038/ijo.2009.302
Nir Eynon
Is there an interaction between PPARD T294C and PPARGC1A Gly482Ser polymorphisms and human endurance performance?
2009
0
Inke Nitz
Analysis of PGC-1alpha variants Gly482Ser and Thr612Met concerning their PPARgamma2-coactivation function.
2007
0
A Maver
Peroxisome proliferator-activated receptor gamma/Pro12Ala polymorphism and peroxisome proliferator-activated receptor gamma coactivator-1 alpha/Gly482Ser polymorphism in patients with sarcoidosis.
2008
0
Evidence compiled by the
Personal Genome Project
There are no results from the
Personal Genome Project
yet. Please come back later.
Publications listed by
Genome.gov
There are no results from
genome.gov
yet. Please come back later.
Users who share this SNP:
Genome Browser