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SNP rs7756992
Basic Information
Name
rs7756992
Chromosome
6
Position
20679478
Weight of evidence
84
Genotype Frequency
Allele Frequency
Additional Information
SNPedia (3)
PLoS (25)
Mendeley (17)
Personal Genome Project (0)
Genome.gov (1)
Other users (1684)
Comments (0)
Links to SNPedia
Title
Summary
rs7756992 A/G
1.3x increased risk for type-2 diabetes
rs7756992 A/A
Normal
rs7756992 G/G
1.3x increased risk for type-2 diabetes
Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).
Publications on this SNP on the Public Library of Science:
First Author
Title
Year of Publication
# of readers
Min Xu
Combined Effects of 19 Common Variations on Type 2 Diabetes in Chinese: Results from Two Community-Based Studies
2010
5222
Qi Zhao
Cross-Sectional and Longitudinal Replication Analyses of Genome-Wide Association Loci of Type 2 Diabetes in Han Chinese
2014
2631
Cheng Hu
PPARG
,
KCNJ11
,
CDKAL1
,
CDKN2A-CDKN2B
,
IDE-KIF11-HHEX
,
IGF2BP2
and
SLC30A8
Are Associated with Type 2 Diabetes in a Chinese Population
2009
8909
Claudia H. T. Tam
Use of Net Reclassification Improvement (NRI) Method Confirms The Utility of Combined Genetic Risk Score to Predict Type 2 Diabetes
2013
5559
Anders Borglykke
Genetic Variant
SCL2A2
Is Associated with Risk of Cardiovascular Disease – Assessing the Individual and Cumulative Effect of 46 Type 2 Diabetes Related Genetic Variants
2012
2487
Xiaomu Kong
Association of Genetic Variants with Isolated Fasting Hyperglycaemia and Isolated Postprandial Hyperglycaemia in a Han Chinese Population
2013
3152
Inga Prokopenko
A Central Role for
GRB10
in Regulation of Islet Function in Man
2014
8990
Raquel Villegas
Joint Effect of Genetic and Lifestyle Risk Factors on Type 2 Diabetes Risk among Chinese Men and Women
2012
3376
Claudia Langenberg
Gene-Lifestyle Interaction and Type 2 Diabetes: The EPIC InterAct Case-Cohort Study
2014
20508
John P.A. Ioannidis
Heterogeneity in Meta-Analyses of Genome-Wide Association Investigations
2007
10623
Vipin Gupta
Association Study of 25 Type 2 Diabetes Related Loci with Measures of Obesity in Indian Sib Pairs
2013
3049
Stéphane Cauchi
Post Genome-Wide Association Studies of Novel Genes Associated with Type 2 Diabetes Show Gene-Gene Interaction and High Predictive Value
2008
12155
Chia Lin Chang
Adaptive Human
CDKAL1
Variants Underlie Hormonal Response Variations at the Enteroinsular Axis
2014
1448
Lang Wu
Do Variants Associated with Susceptibility to Pancreatic Cancer and Type 2 Diabetes Reciprocally Affect Risk?
2015
3983
Yun Qian
Cumulative Effect and Predictive Value of Genetic Variants Associated with Type 2 Diabetes in Han Chinese: A Case-Control Study
2015
2756
Alicia Huerta-Chagoya
Genetic Determinants for Gestational Diabetes Mellitus and Related Metabolic Traits in Mexican Women
2015
5509
Maria A. Matuszek
Increased Insulin following an Oral Glucose Load, Genetic Variation near the Melatonin Receptor
MTNR1B
, but No Biochemical Evidence of Endothelial Dysfunction in Young Asian Men and Women
2015
1455
Xiaomu Kong
The Association of Type 2 Diabetes Loci Identified in Genome-Wide Association Studies with Metabolic Syndrome and Its Components in a Chinese Population with Type 2 Diabetes
2015
2999
Uru Nezu Osada
A Common Susceptibility Gene for Type 2 Diabetes Is Associated with Drug Response to a DPP-4 Inhibitor: Pharmacogenomic Cohort in Okinawa Japan
2016
2052
Hadi Zarkoob
Utilization of genetic data can improve the prediction of type 2 diabetes incidence in a Swedish cohort
2017
1159
Guanjie Chen
Common and rare exonic
MUC5B
variants associated with type 2 diabetes in Han Chinese
2017
1157
Klara Rosta
Association Study with 77 SNPs Confirms the Robust Role for the rs10830963/
G
of
MTNR1B
Variant and Identifies Two Novel Associations in Gestational Diabetes Mellitus Development
2017
2162
Sarah L. O’Beirne
Type 2 Diabetes Risk Allele Loci in the Qatari Population
2016
2145
Jihye Kim
Interaction of iron status with single nucleotide polymorphisms on incidence of type 2 diabetes
2017
1451
Eleanor Wheeler
Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
2017
15689
Publications on this SNP on Mendeley
First Author
Title
Pub. Year
# of Readers
DOI
Xiangdong Liu
Genetic variants of cyclin-dependent kinase 5 regulatory subunit associated protein 1-like 1 and transcription factor 7-like 2 are not associated with polycystic ovary syndrome in Chinese women.
2010
1
-
Jianhua Zhao
Examination of Type 2 Diabetes Loci Implicates CDK4L1 as a Birth Weight Gene
2009
1
10.2337/db09-0506
Hyunju Ryoo
Heterogeneity of genetic associations of CDKAL1 and HHEX with susceptibility of type 2 diabetes mellitus by gender.
2011
7
10.1038/ejhg.2011.6
Yasuharu Tabara
Replication Study of Candidate Genes Associated With Type 2 Diabetes Based On Genome-Wide Screening
2009
10
10.2337/db07-1785
Jianhua Zhao
Examination of Type 2 Diabetes Loci Implicates CDKAL1 as a Birth Weight Gene
2009
11
10.2337/db09-0506
Z Schroner
Variation in CDKAL1 gene is associated with therapeutic response to sulphonylureas.
2012
6
Min Xu
Combined Effects of 19 Common Variations on Type 2 Diabetes in Chinese: Results from Two Community-Based Studies
2010
8
10.1371/journal.pone.0014022
Feng Peng
The relationship between five widely-evaluated variants in CDKN2A/B and CDKAL1 genes and the risk of type 2 diabetes: A meta-analysis
2013
1
10.1016/j.gene.2013.08.075
M Dobríková
Relationship of the CDKAL1 and KCNQ1 gene polymorphisms to the age at diagnosis of type 2 diabetes in the Slovakian population
2011
1
Jianhua Zhao
Examination of type 2 diabetes loci implicates CDKAL1 as a birth weight gene.
2009
11
10.2337/db09-0506
M Horikoshi
Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.
2007
16
-
Z Schroner
Variation in CDKAL1 gene is associated with therapeutic response to sulphonylureas.
2012
1
-
R C W Ma
Genetic variants for type 2 diabetes and new-onset cancer in Chinese with type 2 diabetes.
2013
1
10.1016/j.diabres.2013.12.016
Rita Nemr
Replication study of common variants in CDKAL1 and CDKN2A/2B genes associated with type 2 diabetes in Lebanese Arab population
2012
3
10.1016/j.diabres.2011.11.002
Yan-Yan Li
CDKAL1 gene rs7756992 A/G polymorphism and type 2 diabetes mellitus: a meta-analysis of 62,567 subjects.
2013
2
10.1038/srep03131
Yasuharu Tabara
Replication Study of Candidate Genes Associated With Type 2 Diabetes Based On Genome-Wide Screening
2009
2
10.2337/db07-1785
E A Andersson
Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight.
2010
17
-
Evidence compiled by the
Personal Genome Project
There are no results from the
Personal Genome Project
yet. Please come back later.
Publications listed by
Genome.gov
First Author
Title
Journal
Publication Date
Trait
p-value
Confidence Interval
Steinthorsdottir V
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes.
Nat Genet
04/26/2007
Type 2 diabetes
8.0e-09
[1.13-1.27]
Users who share this SNP:
Genome Browser