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SNP rs5370
Basic Information
Name
rs5370
Chromosome
6
Position
12296022
Weight of evidence
48
Genotype Frequency
Allele Frequency
Additional Information
SNPedia (3)
PLoS (3)
Mendeley (25)
Personal Genome Project (1)
Genome.gov (0)
Other users (1706)
Comments (0)
Links to SNPedia
Title
Summary
rs5370 T/T
Possibly lower hdl cholesterol in women
rs5370 G/T
Possibly lower hdl cholesterol in women
rs5370 G/G
Common
Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).
Publications on this SNP on the Public Library of Science:
First Author
Title
Year of Publication
# of readers
Xiaofang Zang
Endothelin-1 Single Nucleotide Polymorphisms and Risk of Pulmonary Metastatic Osteosarcoma
2013
1446
Ashham Mansur
Genetic Polymorphisms in Endothelin-1 as Predictors for Long-Term Survival and the Cardiac Index in Patients Undergoing On-Pump Cardiac Surgery
2015
1210
Vanesa Martínez-Barquero
Polymorphisms in Endothelin System Genes, Arsenic Levels and Obesity Risk
2015
2301
Publications on this SNP on Mendeley
First Author
Title
Pub. Year
# of Readers
DOI
Guillaume Pare
Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol.
2007
24
10.1086/513286
Ai Mantaka
Polymorphisms of genes related to endothelial cells are associated with primary biliary cirrhosis patients of Cretan origin.
2012
1
10.1016/j.humimm.2012.05.003
Guillaume Paré
Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol.
2007
20
-
G Pare
Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol
2007
2
10.1086/513286
Y Uchida
Endothelin-1 gene polymorphism and hearing impairment in elderly Japanese
2009
2
10.1002/lary.20181
D S Cross
Association of alleles from inflammatory, vaso-architecture, and coagulation pathways with clinical characteristics of a deep vein thrombosis
2010
1
-
Yasue Uchida
Endothelin‐1 gene polymorphism in sudden sensorineural hearing loss
2013
1
10.1002/lary.24298
G Zhu
Polymorphisms in the endothelin-1 (EDN1) are associated with asthma in two populations.
2008
0
Hyun-Jin Kim
The association between endothelin-1 gene polymorphisms and susceptibility to vitiligo in a Korean population.
2007
0
William J Geese
Genetic and gene expression studies implicate renin and endothelin-1 in edema caused by peroxisome proliferator-activated receptor gamma agonists.
2008
5
10.1097/FPC.0b013e32830a6ea0
Shivani Vadapalli
Endothelin-1 and endothelial nitric oxide polymorphisms in idiopathic pulmonary arterial hypertension.
2010
1
Shivani Vadapalli
Endothelin-1 and endothelial nitric oxide polymorphisms in idiopathic pulmonary arterial hypertension.
2010
2
Yasue Uchida
Endothelin-1 gene polymorphism and hearing impairment in elderly Japanese.
2009
4
10.1002/lary.20181
Yasue Uchida
Endothelin-1 gene polymorphism and hearing impairment in elderly Japanese.
2009
2
-
Ai Mantaka
Polymorphisms of genes related to endothelial cells are associated with primary biliary cirrhosis patients of Cretan origin
2012
1
10.1016/j.humimm.2012.05.003
Castillo J. Moldes O., Sobrino T., Rodriguez-Yanez M., Rodriguez-Gonzalez R., Argibay B., Campos F., Blanco M., Leira R.
Clinical significance of the presence of endothelin-1 gene rs1800541 and rs5370 SNPs in patients with acute ischemic stroke
2011
2
-
Yasue Uchida
Endothelin-1 gene polymorphism in sudden sensorineural hearing loss.
2013
1
10.1002/lary.24298
G Zhu
Polymorphisms in the endothelin-1 (EDN1) are associated with asthma in two populations.
2008
4
10.1038/sj.gene.6364441
Moldes O.
Clinical significance of the presence of endothelin-1 gene rs1800541 and rs5370 SNPs in patients with acute ischemic stroke
2011
1
-
Ai Mantaka
Polymorphisms of genes related to endothelial cells are associated with primary biliary cirrhosis patients of Cretan origin.
2012
0
10.1016/j.humimm.2012.05.003
N Verweij
Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1
2013
1
10.1161/HYPERTENSIONAHA.111.203117
Niek Verweij
Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1.
2013
1
10.1161/HYPERTENSIONAHA.111.203117
N Verweij
Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1
2013
1
10.1161/HYPERTENSIONAHA.111.203117
Tuomo Rankinen
Effect of endothelin 1 genotype on blood pressure is dependent on physical activity or fitness levels.
2007
10
-
Tuomo Rankinen
Effect of endothelin 1 genotype on blood pressure is dependent on physical activity or fitness levels.
2007
11
10.1161/HYPERTENSIONAHA.107.093609
Evidence compiled by the
Personal Genome Project
Gene
Impact
Trait
Summary
Inheritance
EDN1
Insufficiently evaluated pathogenic
Associated with lower HDL cholesterol levels in women.
unknown
Publications listed by
Genome.gov
There are no results from
genome.gov
yet. Please come back later.
Users who share this SNP:
Genome Browser