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SNP rs4818
Basic Information
Name
rs4818
Chromosome
22
Position
19963684
Weight of evidence
53
Genotype Frequency
Allele Frequency
Additional Information
SNPedia (1)
PLoS (10)
Mendeley (28)
Personal Genome Project (0)
Genome.gov (0)
Other users (11)
Comments (0)
Links to SNPedia
Title
Summary
rs4818 C/G
No summary provided.
Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).
Publications on this SNP on the Public Library of Science:
First Author
Title
Year of Publication
# of readers
Elisabet Cuyàs
The Influence of Genetic and Environmental Factors among MDMA Users in Cognitive Performance
2011
5872
Leandro Fernandes Malloy-Diniz
Association between the Catechol O-Methyltransferase (COMT) Val158met Polymorphism and Different Dimensions of Impulsivity
2013
3346
Lori D. Hill
Epistasis between
COMT
and
MTHFR
in Maternal-Fetal Dyads Increases Risk for Preeclampsia
2011
5465
Lauren E. Kelly
A Clinical Tool for Reducing Central Nervous System Depression among Neonates Exposed to Codeine through Breast Milk
2013
3965
Andrea G. Nackley
Low Enzymatic Activity Haplotypes of the Human Catechol-O-Methyltransferase Gene: Enrichment for Marker SNPs
2009
5542
Sofia I. I. Kring
Polymorphisms of Serotonin Receptor 2A and 2C Genes and
COMT
in Relation to Obesity and Type 2 Diabetes
2009
6547
Shui Ying Tsang
Social Cognitive Role of Schizophrenia Candidate Gene
GABRB2
2013
3159
Brian E. Roe
Financial and Psychological Risk Attitudes Associated with Two Single Nucleotide Polymorphisms in the Nicotine Receptor (
CHRNA4
) Gene
2009
6452
Ting Li
Role of Novelty Seeking Personality Traits as Mediator of the Association between COMT and Onset Age of Drug Use in Chinese Heroin Dependent Patients
2011
4351
Ansley Stanfill
A Pilot Study of Demographic and Dopaminergic Genetic Contributions to Weight Change in Kidney Transplant Recipients
2015
1239
Publications on this SNP on Mendeley
First Author
Title
Pub. Year
# of Readers
DOI
Neslihan Aygun Kocabas
Kocabas.COMT SNPs and haplotypes impact on antidepressant treatment response.pdf
2010
3
10.1097/YIC.0b013e328338b884
Peter J Lee
Catecholamine-O-Methyltransferase Polymorphisms are Associated With Postoperative Pain Intensity.
2010
1
10.1097/AJP.0b013e3181f15885
Herbert Oberacher
Direct molecular haplotyping of multiple polymorphisms within exon 4 of the human catechol-O-methyltransferase gene by liquid chromatography-electrospray ionization time-of-flight mass spectrometry.
2006
11
-
Yuko Hirata
Study of the catechol-o-methyltransferase (COMT) gene with high aggression in children.
2013
4
10.1002/ab.21448
Miriam S Udler
Common germline polymorphisms in COMT, CYP19A1, ESR1, PGR, SULT1E1 and STS and survival after a diagnosis of breast cancer.
2009
13
10.1016/S1043-321X(10)79523-0
Barbara I Nicholl
No evidence for a role of the catechol-O-methyltransferase pain sensitivity haplotypes in chronic widespread pain.
2010
7
-
Yong Zhang
Correlation of domestic violence during pregnancy with plasma amino-acid neurotransmitter, cortisol levels and catechol-o-methyltransferase Val(158)Met polymorphism in neonates.
2013
3
10.1111/appy.12021
Zeynep Yilmaz
COMT Val158Met variant and functional haplotypes associated with childhood ADHD history in women with bulimia nervosa.
2011
6
-
Miriam S Udler
Common germline polymorphisms in COMT, CYP19A1, ESR1, PGR, SULT1E1 and STS and survival after a diagnosis of breast cancer
2009
11
-
A P Shimamura
Memory interference effects and aging: Findings from a test of frontal lobe function
1994
7
10.1016/j.biopsych.2009.07.008
M Martínez-Jauand
Pain sensitivity in fibromyalgia is associated with catechol-O-methyltransferase (COMT) gene.
2012
4
10.1002/j.1532-2149.2012.00153.x
Panos Roussos
Planning, decision-making and the COMT rs4818 polymorphism in healthy males.
2008
34
-
Jennifer H Barnett
NIH Public Access
2009
1
10.1176/appi.ajp.2009.08081251.Effects
Amy F T Arnsten
Through the Looking Glass: Differential Noradenergic Modulation of Prefrontal Cortical Function
2000
2
10.1155/NP.2000.133
Monika Bialecka
The association of functional catechol-O-methyltransferase haplotypes with risk of Parkinson's disease, levodopa treatment response, and complications.
2008
5
-
Jennifer H Barnett
Effects of catechol-O-methyltransferase on normal variation in the cognitive function of children.
2009
33
10.1176/appi.ajp.2009.08081251
Panos Roussos
Planning, decision-making and the COMT rs4818 polymorphism in healthy males.
2008
38
10.1016/j.neuropsychologia.2007.10.009
Wen Jun Li
Cf-32】Association of catechol-O-methyltransferase gene polymorphisms with schizophrenia and negative symptoms in a Chinese population.
2012
3
10.1002/ajmg.b.32038
Peter J Lee
Catecholamine-o-methyltransferase polymorphisms are associated with postoperative pain intensity.
2011
1
10.1097/AJP.0b013e3181f15885
Janet Hoenicka
Gender-specific COMT Val158Met polymorphism association in Spanish schizophrenic patients.
2010
7
-
Wen Jun Li
Association of catechol-O-methyltransferase gene polymorphisms with schizophrenia and negative symptoms in a Chinese population.
2012
4
10.1002/ajmg.b.32038
Panos Roussos
Tolcapone effects on gating, working memory, and mood interact with the synonymous catechol-O-methyltransferase rs4818c/g polymorphism.
2009
15
10.1016/j.biopsych.2009.07.008
Guanshan Zhu
Differential expression of human COMT alleles in brain and lymphoblasts detected by RT-coupled 5' nuclease assay.
2004
14
-
Panos Roussos
Tolcapone effects on gating, working memory, and mood interact with the synonymous catechol-O-methyltransferase rs4818c/g polymorphism.
2009
13
-
Panos Roussos
Planning, decision-making and the COMT rs4818 polymorphism in healthy males
2008
46
10.1016/j.neuropsychologia.2007.10.009
P J Lee
Catecholamine-O-Methyltransferase Polymorphisms are Associated With Postoperative Pain Intensity
2010
1
10.1097/AJP.0b013e3181f15885
Hiroshi Hirata
COMT polymorphisms affecting protein expression are risk factors for endometrial cancer.
2008
3
-
Yuko Hirata
Study of the Catechol-O-Methyltransferase (COMT) Gene with High Aggression in Children.
2013
3
10.1002/ab.21448
Evidence compiled by the
Personal Genome Project
There are no results from the
Personal Genome Project
yet. Please come back later.
Publications listed by
Genome.gov
There are no results from
genome.gov
yet. Please come back later.
Users who share this SNP:
Genome Browser