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SNP rs4588
Basic Information
Name
rs4588
Chromosome
4
Position
71752606
Weight of evidence
60
Genotype Frequency
Allele Frequency
Additional Information
SNPedia (1)
PLoS (22)
Mendeley (11)
Personal Genome Project (0)
Genome.gov (0)
Other users (869)
Comments (0)
Links to SNPedia
Title
Summary
rs4588 C/C
Common in clinvar
Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).
Publications on this SNP on the Public Library of Science:
First Author
Title
Year of Publication
# of readers
Edmondo Falleti
Genetic Polymorphisms of Vitamin D Pathway Predict Antiviral Treatment Outcome in Slow Responder Naïve Patients with Chronic Hepatitis C
2013
2612
Georgios Grammatikos
Vitamin D Levels Vary during Antiviral Treatment but Are Unable to Predict Treatment Outcome in HCV Genotype 1 Infected Patients
2014
2875
Maria Peña-Chilet
rs12512631 on the Group Specific Complement (Vitamin D-Binding Protein
GC
) Implicated in Melanoma Susceptibility
2013
2298
Linda Larcombe
Vitamin D in a Northern Canadian First Nation Population: Dietary Intake, Serum Concentrations and Functional Gene Polymorphisms
2012
3559
Jen-Chieh Chang
Different Genetic Associations of the IgE Production among Fetus, Infancy and Childhood
2013
2126
Diane J. Berry
Evaluation of Genetic Markers as Instruments for Mendelian Randomization Studies on Vitamin D
2012
5779
Minna Pekkinen
Vitamin D Binding Protein Genotype Is Associated with Serum 25-Hydroxyvitamin D and PTH Concentrations, as Well as Bone Health in Children and Adolescents in Finland
2014
4185
Amardeep Singh
The Association between Plasma 25-Hydroxyvitamin D and Subgroups in Age-Related Macular Degeneration: A Cross-Sectional Study
2013
3227
Janna Nissen
Common Variants in
CYP2R1
and
GC
Genes Predict Vitamin D Concentrations in Healthy Danish Children and Adults
2014
5177
Tilman Kühn
Plasma 25-Hydroxyvitamin D and Its Genetic Determinants in Relation to Incident Myocardial Infarction and Stroke in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Germany Study
2013
3646
Cholendra Arja
Genetic Determinants of Chronic Obstructive Pulmonary Disease in South Indian Male Smokers
2014
2721
Anna K. Coussens
Ethnic Variation in Inflammatory Profile in Tuberculosis
2013
9042
Lisa B. Signorello
Common Variation in Vitamin D Pathway Genes Predicts Circulating 25-Hydroxyvitamin D Levels among African Americans
2011
6067
Song Yao
Common Genetic Variants Are Associated with Accelerated Bone Mineral Density Loss after Hematopoietic Cell Transplantation
2011
2647
Laura N. Anderson
Genetic Variants in Vitamin D Pathway Genes and Risk of Pancreas Cancer; Results from a Population-Based Case-Control Study in Ontario, Canada
2013
3079
Rolf Jorde
The DBP Phenotype Gc-1f/Gc-1f Is Associated with Reduced Risk of Cancer. The Tromsø Study
2015
1920
Mayuko Tamura
Detection of Hereditary 1,25-Hydroxyvitamin D-Resistant Rickets Caused by Uniparental Disomy of Chromosome 12 Using Genome-Wide Single Nucleotide Polymorphism Array
2015
1967
Amita Gupta
Low Vitamin-D Levels Combined with
PKP3-SIGIRR-TMEM16J
Host Variants Is Associated with Tuberculosis and Death in HIV-Infected and -Exposed Infants
2016
2126
Betânia Rodrigues Santos
Genetic variant in vitamin D-binding protein is associated with metabolic syndrome and lower 25-hydroxyvitamin D levels in polycystic ovary syndrome: A cross-sectional study
2017
2332
Kessarin Thanapirom
Genetic variation in the vitamin D pathway
CYP2R1
gene predicts sustained HBeAg seroconversion in chronic hepatitis B patients treated with pegylated interferon: A multicenter study
2017
1591
Sanjeev Budhathoki
Vitamin D Receptor Gene Polymorphism and the Risk of Colorectal Cancer: A Nested Case-Control Study
2016
1871
Maija E. Miettinen
Genetic determinants of serum 25-hydroxyvitamin D concentration during pregnancy and type 1 diabetes in the child
2017
2604
Publications on this SNP on Mendeley
First Author
Title
Pub. Year
# of Readers
DOI
Edmondo Falleti
Vitamin D binding protein gene polymorphisms and baseline vitamin D levels as predictors of antiviral response in chronic hepatitis C.
2012
4
10.1002/hep.25848
Hataikarn Nimitphong
Changes in circulating 25-hydroxyvitamin D according to vitamin D binding protein genotypes after vitamin D₃ or D₂supplementation.
2013
12
10.1186/1475-2891-12-39
Dustin Blanton
Reduced Serum Vitamin D-Binding Protein Levels Are Associated With Type 1 Diabetes.
2011
4
10.2337/db11-0576
M Mahmoud
Lack of association of Vitamin D Binding Protein Polymorphisms in Egyptian Children with Type 1 Diabetes
2011
2
Ling Lu
Associations between common variants in GC and DHCR7/NADSYN1 and vitamin D concentration in Chinese Hans.
2012
4
10.1007/s00439-011-1099-1
Josephia R Muindi
Serum vitamin D metabolites in colorectal cancer patients receiving cholecalciferol supplementation: correlation with polymorphisms in the vitamin D genes.
2013
4
10.1007/s12672-013-0139-9
Janna Nissen
Common variants in CYP2R1 and GC genes predict vitamin D concentrations in healthy Danish children
2014
1
10.1371/journal.pone.0089907
Hataikarn Nimitphong
Changes in circulating 25-hydroxyvitamin D according to vitamin D binding protein genotypes after vitamin D₃ or D₂supplementation.
2013
7
10.1186/1475-2891-12-39
Corinne D Engelman
Genetic and Environmental Determinants of 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Levels in Hispanic and African Americans
2008
15
10.1210/jc.2007-2702
Minna Pekkinen
Vitamin D Binding Protein Genotype Is Associated with Serum 25-Hydroxyvitamin D and PTH Concentrations, as Well as Bone Health in Children and Adolescents in Finland.
2014
3
10.1371/journal.pone.0087292
Hataikarn Nimitphong
Changes in circulating 25-hydroxyvitamin d according to vitamin D binding protein genotypes after vitamin D3 or D2 supplementation.
2013
4
10.1186/1475-2891-12-39
Evidence compiled by the
Personal Genome Project
There are no results from the
Personal Genome Project
yet. Please come back later.
Publications listed by
Genome.gov
There are no results from
genome.gov
yet. Please come back later.
Users who share this SNP:
Genome Browser