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SNP rs2070600
Basic Information
Name
rs2070600
Chromosome
6
Position
32183666
Weight of evidence
91
Genotype Frequency
Allele Frequency
Additional Information
SNPedia (3)
PLoS (19)
Mendeley (34)
Personal Genome Project (0)
Genome.gov (2)
Other users (886)
Comments (0)
Links to SNPedia
Title
Summary
rs2070600 G/G
Normal
rs2070600 A/G
1.5x increased risk for gastric cancer
rs2070600 A/A
1.5x increased risk for gastric cancer
Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa).
Publications on this SNP on the Public Library of Science:
First Author
Title
Year of Publication
# of readers
Jeffrey J. W. Verschuren
Systematic Testing of Literature Reported Genetic Variation Associated with Coronary Restenosis: Results of the GENDER Study
2012
2110
Cristina Cunha
Genetically-Determined Hyperfunction of the S100B/RAGE Axis Is a Risk Factor for Aspergillosis in Stem Cell Transplant Recipients
2011
3963
Robert P. Young
Individual and Cumulative Effects of GWAS Susceptibility Loci in Lung Cancer: Associations after Sub-Phenotyping for COPD
2011
5781
Jun Wang
Meta-Analysis of
RAGE
Gene Polymorphism and Coronary Heart Disease Risk
2012
2527
Ilana Blech
Predicting Diabetic Nephropathy Using a Multifactorial Genetic Model
2011
4643
Feng Peng
Association of Four Genetic Polymorphisms of
AGER
and Its Circulating Forms with Coronary Artery Disease: A Meta-Analysis
2013
2718
Xiaohong Yu
An Interactive Association of Advanced Glycation End-Product Receptor Gene Four Common Polymorphisms with Coronary Artery Disease in Northeastern Han Chinese
2013
1635
Maria Sabater-Lleal
Common Genetic Determinants of Lung Function, Subclinical Atherosclerosis and Risk of Coronary Artery Disease
2014
2227
Julie Beucher
AGER
-429T/C Is Associated with an Increased Lung Disease Severity in Cystic Fibrosis
2012
2549
Dana B. Hancock
Genome-Wide Joint Meta-Analysis of SNP and SNP-by-Smoking Interaction Identifies Novel Loci for Pulmonary Function
2012
14543
Hongming Pan
Contributory Role of Five Common Polymorphisms of
RAGE
and
APE1
Genes in Lung Cancer among Han Chinese
2013
2320
Nisa M. Maruthur
Genetics of Plasma Soluble Receptor for Advanced Glycation End-Products and Cardiovascular Outcomes in a Community-based Population: Results from the Atherosclerosis Risk in Communities Study
2015
1828
Erik Biros
Association between the Advanced Glycosylation End Product-Specific Receptor Gene and Cardiovascular Death in Older Men
2015
1251
Kei Onodera
Low-Frequency
IL23R
Coding Variant Associated with Crohn’s Disease Susceptibility in Japanese Subjects Identified by Personal Genomics Analysis
2015
1587
Suzanne Miller
The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production
In Vitro
2016
1852
Wei Sun
Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD
2016
4960
John Platig
Bipartite Community Structure of eQTLs
2016
3198
Lasse Folkersen
Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease
2017
4959
Benjamin Goudey
Interactions within the MHC contribute to the genetic architecture of celiac disease
2017
1837
Publications on this SNP on Mendeley
First Author
Title
Pub. Year
# of Readers
DOI
Jonny Daborg
Association of the RAGE G82S polymorphism with Alzheimer's disease.
2010
18
10.1007/s00702-010-0437-0
J Forbes
Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes
2011
1
Suganthalakshmi Balasubbu
Association analysis of nine candidate gene polymorphisms in Indian patients with type 2 diabetic retinopathy
2010
9
10.1186/1471-2350-11-158
Weixin Lu
Association of AGER gene G82S polymorphism with the severity of coronary artery disease in Chinese Han population.
2011
0
10.1111/j.1365-2265.2011.04079.x
Peipei Kang
Association of RAGE gene polymorphisms with type 2 diabetes mellitus, diabetic retinopathy and diabetic nephropathy
2012
-
Peipei Kang
Association of RAGE gene polymorphisms with type 2 diabetes mellitus, diabetic retinopathy and diabetic nephropathy.
2012
4
10.1016/j.gene.2012.03.056
T Hirota
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population
2011
2
10.1038/ng.887
T Hirota
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population
2011
3
10.1038/ng.887
Jonny Daborg
Association of the RAGE G82S polymorphism with Alzheimer’s disease
2010
13
10.1007/s00702-010-0437-0
D T Cheng
Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease
2013
2
10.1164/rccm.201302-0247OC
Peipei Kang
Association of RAGE gene polymorphisms with type 2 diabetes mellitus, diabetic retinopathy and diabetic nephropathy.
2012
2
10.1016/j.gene.2012.03.056
Donavan T Cheng
Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease.
2013
7
10.1164/rccm.201302-0247OC
Tomomitsu Hirota
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.
2011
23
10.1038/ng.887
Katrien H J Gaens
Association of polymorphism in the receptor for advanced glycation end products (RAGE) gene with circulating RAGE levels.
2009
10
-
Katrien H J Gaens
Association of Polymorphism in the Receptor for Advanced Glycation End Products ( RAGE ) Gene with
2009
2
10.1210/jc.2009-1067
T Hirota
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population
2011
13
10.1038/ng.887
C C Boiocchi
RAGE (receptor for advanced glycation endproducts) polymorphisms in Alzheimer Disease
2010
1
http://dx.doi.org/10.1111/j.1399-0039.2010.01488.x
Kirsi M Salonen
Circulating Concentrations of Soluble Receptor for AGE Are Associated With Age and AGER Gene Polymorphisms in Children With Newly Diagnosed Type 1 Diabetes.
2014
1
10.2337/dc13-3049
A C Goulart
Polymorphisms in advanced glycosylation end product-specific receptor (AGER) gene, insulin resistance, and type 2 diabetes mellitus
2008
0
Megan Hardin
CHRNA3/5, IREB2, and ADCY2 Are Associated with Severe Chronic Obstructive Pulmonary Disease in Poland.
2012
2
10.1165/rcmb.2012-0011OC
A C Goulart
Polymorphisms in advanced glycosylation end product-specific receptor (AGER) gene, insulin resistance, and type 2 diabetes mellitus.
2008
4
10.1016/j.cca.2008.08.020
M C Torres
Polymorphisms of the promoter and exon 3 of the receptor for advanced glycation end products (RAGE) in Euro- and Afro-Brazilians.
2011
1
10.1111/j.1744-313X.2011.01073.x
Jing Yang
Association of five genetic variants with chronic obstructive pulmonary disease susceptibility and spirometric phenotypes in a Chinese Han population.
2013
3
10.1111/resp.12212
Songpo Yao
Association between the RAGE G82S polymorphism and Alzheimer’s disease
2010
5
10.1007/s00702-009-0334-6
Katrien H J Gaens
Association of polymorphism in the receptor for advanced glycation end products (RAGE) gene with circulating RAGE levels.
2009
13
10.1210/jc.2009-1067
M C Torres
Polymorphisms of the promoter and exon 3 of the receptor for advanced glycation end products (RAGE) in Euro- and Afro-Brazilians.
2011
1
10.1111/j.1744-313X.2011.01073.x
Weixin Lu
Association of AGER gene G82S polymorphism with the severity of coronary artery disease in Chinese Han population.
2011
0
10.1111/j.1365-2265.2011.04079.x
C C Boiocchi
RAGE (receptor for advanced glycation endproducts) polymorphisms in Alzheimer Disease
2010
1
10.1111/j.1399-0039.2010.01488.x
T Hirota
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population
2011
1
Jan Däbritz
The functional -374T/A polymorphism of the receptor for advanced glycation end products may modulate Crohn's disease.
2011
7
-
Keshen Li
Association between the RAGE G82S polymorphism and Alzheimer's disease.
2010
8
-
Zhu Han
The Interaction Between Obesity and RAGE Polymorphisms on the Risk of Knee Osteoarthritis in Chinese Population.
2012
1
10.1159/000341467
Jan Däbritz
The functional -374T/A polymorphism of the receptor for advanced glycation end products may modulate Crohn's disease.
2011
8
10.1152/ajpgi.00115.2010
Petra Suchankova
Is the Gly82Ser polymorphism in the RAGE gene relevant to schizophrenia and the personality trait psychoticism?
2012
8
10.1503/jpn.110024
Evidence compiled by the
Personal Genome Project
There are no results from the
Personal Genome Project
yet. Please come back later.
Publications listed by
Genome.gov
First Author
Title
Journal
Publication Date
Trait
p-value
Confidence Interval
Hancock DB
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.
Nat Genet
12/13/2009
Pulmonary function
3.0e-14 (FEV1/FVC)
[NR] % increase
Repapi E
Genome-wide association study identifies five loci associated with lung function.
Nat Genet
12/13/2009
Pulmonary function
3.0e-15 (FEV1/FVC)
[NR] % variance explained
Users who share this SNP:
Genome Browser